Halestrap AP
From Bioblast
| Name | Halestrap Andrew P, Prof. |
|---|---|
| Institution | Department of Biochemistry
School of Med. Sciences University of Bristol |
| Address | University Walk, BS8 1TD |
| City | Bristol |
| State/Province | |
| Country | United Kingdom |
| [email protected] | |
| Weblink | |
| O2k-Network Lab | UK Bristol Halestrap AP |
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Publications
| Published | Reference | |
|---|---|---|
| Knapp-Wilson 2021 J Cell Sci | 2021 | Knapp-Wilson A, Pereira GC, Buzzard E, Ford HC, Richardson A, Corey RA, Neal C, Verkade P, Halestrap AP, Gold VAM, Kuwabara PE, Collinson I (2021) Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health. J Cell Sci 134:jcs258399. https://doi.org/10.1242/jcs.258399 |
| Pereira 2020 PLoS One | 2020 | Pereira GC, Lee L, Rawlings N, Ouwendijk J, Parker JE, Andrienko TN, Henley JM, Halestrap AP (2020) Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia. PLoS One 15:e0234653. |
| Andrienko 2017 J Mol Cell Cardiol | 2017 | Andrienko TN, Pasdois P, Pereira GC, Ovens MJ, Halestrap AP (2017) The role of succinate and ROS in reperfusion injury - a critical appraisal. J Mol Cell Cardiol 110:1-14. doi: 10.1016/j.yjmcc.2017.06.016 |
| Hansson 2015 Eur J Pharmacol | 2015 | Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19. |
| Littlejohns 2014 PLoS One | 2014 | Littlejohns B, Pasdois P, Duggan S, Bond AR, Heesom K, Jackson CL, Angelini GD, Halestrap AP, Suleiman MS (2014) Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. PLoS One 9:e100579. |
| Pasdois 2012 J Am Heart Assoc | 2012 | Pasdois P, Parker JE, Halestrap AP (2012) Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion. J Am Heart Assoc 2:e005645. |
| Pasdois 2011 Biochem J | 2011 | Pasdois P, Parker JE, Griffiths EJ, Halestrap AP (2011) The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia. Biochem J 436:493-505. |
| Hildyard 2003 Biochem J | 2003 | Hildyard JC, Halestrap AP (2003) Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae. Biochem J 374: 607-611. |
| Griffiths 1995 Biochem J | 1995 | Griffiths EJ, Halestrap AP (1995) Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem J 307:93-98. |
| Halestrap 1986 Biochem J | 1986 | Halestrap AP, Dunlop JL (1986) Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J 239:559-65. https://doi.org/10.1042/bj2390559 |
Abstracts
| Published | Reference | |
|---|---|---|
| Pereira 2015 Abstract MiPschool London 2015 | 2015 | Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology. |
