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AT Vienna Kozlov AV

From Bioblast

                



AT Vienna Kozlov AV

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Ludwig Boltzmann Institute for Traumatology

The Research Center in Cooperation with AUVA

Address Donaueschingen-Str. 13, A-1200
City Vienna
State/Prov
Country Austria
Weblink
Contact Kozlov Andrey V
Team Behling Tricia, Dungel Peter, Duvigneau Johanna, Redl Heinz, Singer Katharina, Wagner Carina, Weidinger Adelheid, Zipperle Johannes
Team previous Bahrami Soheyl, Paier-Pourani Jamille, Piskernik Christina, Haindl Susanne
Status 3 Power-O2k 2004-
Oroboros Events IOC154, MitoFit Science Camp 2016, MiP2013, Bioblast 2012, IOC88, IOC31, IOC28, IOC26, IOC23, IOC19
Topics


O2k-Publications

 PublishedReference
Heher 2022 Redox Biol2022Heher P, Ganassi M, Weidinger A, Engquist EN, Pruller J, Nguyen TH, Tassin A, Declèves AE, Mamchaoui K, Banerji CRS, Grillari J, Kozlov AV, Zammit PS (2022) Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target. https://doi.org/10.1016/j.redox.2022.102251
Hosmann 2020 Acta Neurochir (Wien)2020Hosmann A, Milivojev N, Dumitrescu S, Reinprecht A, Weidinger A, Kozlov AV (2020) Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach. Acta Neurochir (Wien) 163:139-49.
Zavadskis 2020 Pharmaceutics2020Zavadskis S, Weidinger A, Hanetseder D, Banerjee A, Schneider C, Wolbank S, Marolt Presen D, Kozlov AV (2020) Effect of diphenyleneiodonium chloride on intracellular reactive oxygen species metabolism with emphasis on NADPH oxidase and mitochondria in two therapeutically relevant human cell types. Pharmaceutics 13:E10.
Pozenel 2019 Cells2019Pozenel L, Lindenmair A, Schmidt K, Kozlov AV, Grillari J, Wolbank S, Banerjee A, Weidinger A (2019) Critical impact of human amniotic membrane tension on mitochondrial function and cell viability in vitro. Cells 8:E1641.
Banerjee 2018 Cell Transplant2018Banerjee A*, Lindenmair A, Hennerbichler S, Steindorf P, Steinborn R, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Cellular and site-specific mitochondrial characterization of vital human amniotic membrane. Cell Transplant 27:3-11.
Mkrtchyan 2018 Biochim Biophys Acta2018Mkrtchyan GV, Üçal M, Müllebner A, Dumitrescu S, Kames M, Moldzio R, Molcanyi M, Schaefer S, Weidinger A, Schaefer U, Hescheler J, Duvigneau JC, Redl H, Bunik VI, Kozlov AV (2018) Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex. Biochim Biophys Acta 1859:925-31.
Banerjee 2018 Stem Cells Int2018Banerjee A, Lindenmair A, Steinborn R, Dumitrescu SD, Hennerbichler S, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Oxygen tension strongly influences metabolic parameters and the release of interleukine-6 of human amniotic mesenchymal stromal cells in vitro. Stem Cells Int 2018:9502451.
Zdralevic 2018 J Biol Chem2018Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M (2018) Double genetic disruption of lactate dehydrogenase A and B is required to ablate the 'Warburg effect' restricting tumor growth to oxidative metabolism. J Biol Chem 293:15947-61.
Cronin 2018 Nature2018Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68.
Rademann 2017 Oxid Med Cell Longev2017Rademann P, Weidinger A, Drechsler S, Meszaros A, Zipperle J, Jafarmadar M, Dumitrescu S, Hacobian A, Ungelenk L, Röstel F, Kaszaki J, Szabo A, Skulachev VP, Bauer M, Bahrami S, Weis S, Kozlov AV, Osuchowski MF (2017) Mitochondria-targeted antioxidants SKQ1 and MitoTEMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis. Oxid Med Cell Longev 6412682.
Uecal 2016 J Neurotrauma2016Üçal M, Kraitsy K, Weidinger A, Paier-Pourani J, Patz S, Fink B, Molcanyi M, Schäfer U (2016) Comprehensive profiling of modulation of nitric oxide levels and mitochondrial activity in the injured brain: an experimental study based on the fluid percussion injury model in rats. J Neurotrauma 34:475-86.
Banerjee 2015 Placenta2015Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32.
Renner 2015 Eur J Immunol2015Renner K, Geiselhöringer AL, Fante M, Bruss C, Färber S, Schönhammer G, Peter K, Singer K, Andreesen R, Hoffmann P, Oefner P, Herr W, Kreutz M (2015) Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions. Eur J Immunol 45:2504-16.
Weidinger 2015 Antioxid Redox Signal2015Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.
Dungel 2015 Free Radic Biol Med2015Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.
Drechsler 2015 Intensive Care Medicine Experimental2015Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.
Muellebner 2015 Biomolecules2015Müllebner A, Moldzio R, Redl H, Kozlov AV, Duvigneau JC (2015) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701.
Weidinger 2013 Front Physiol2013Weidinger A, Dungel P, Perlinger M, Singer K, Ghebes C, Duvigneau JC, Müllebner A, Schäfer U, Redl H, Kozlov AV (2013) Experimental data suggesting that inflammation mediated rat liver mitochondrial dysfunction results from secondary hypoxia rather than from direct effects of inflammatory mediators. Front Physiol 4:138.
Dungel 2011 J Biochem Mol Toxicol2011Dungel P, Haindl S, Behling T, Mayer B, Redl H, Kozlov AV (2011) Neither nitrite nor nitric oxide mediate toxic effects of nitroglycerin on mitochondria. J Biochem Mol Toxicol 25:297-302.
Tan 2011 Inflammation2011Tan EC, van Goor H, Bahrami Sl, Kozlov AV, Leixnering M, Redl H, Goris RJ (2011) Intra-arterial tert-Butyl-hydroperoxide infusion induces an exacerbated sensory response in the rat hind limb and is associated with an impaired tissue oxygen uptake. Inflammation 34:49-57.
Duvigneau 2010 Shock2010Duvigneau JC, Kozlov AV, Zifko C, Postl A, Hartl RT, Miller I, Gille L, Staniek K, Moldzio R, Gregor W, Haindl S, Behling T, Redl H, Bahrami Sl (2010) Reperfusion does not induce oxidative stress but sustained endoplasmic reticulum stress in livers of rats subjected to traumatic/hemorrhagic shock. Shock 33:289-98.
Kozlov 2010 Inflammation2010Kozlov AV, van Griensven M, Haindl S, Kehrer I, Duvigneau JC, Hartl RT, Ebel T, Jafarmadar M, Calzia E, Gnaiger E, Redl H, Radermacher P, Bahrami Sl (2010) Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney. Inflammation 33:295-305.
Kozlov 2009 Biochim Biophys Acta2009Kozlov AV, Duvigneau JC, Miller I, Nürnberger S, Gesslbauer B, Kungl A, Ohlinger W, Hartl RT, Gille L, Staniek K, Gregor W, Haindl S, Redl H (2009) Endotoxin causes functional endoplasmic reticulum failure, possibly mediated by mitochondria. Biochim Biophys Acta 1792:521-30.
Dungel 2008 Arch Biochem Biophys2008Dungel P, Mittermayr R, Haindl S, Osipov A, Wagner C, Redl H, Kozlov AV (2008) Illumination with blue light reactivates respiratory activity of mitochondria inhibited by nitric oxide, but not by glycerol trinitrate. Arch Biochem Biophys 471:109-15.
Piskernik 2008 Biochim Biophys Acta2008Piskernik C, Haindl S, Behling T, Gerald Z, Kehrer I, Redl H, Kozlov AV (2008) Antimycin A and lipopolysaccharide cause the leakage of superoxide radicals from rat liver mitochondria. Biochim Biophys Acta 1782:280-5.
Miller 2006 FEBS Lett2006Miller I, Gemeiner M, Gesslbauer B, Kungl A, Piskernik C, Haindl S, Nürnberger S, Bahrami Sl, Redl H, Kozlov AV (2006) Proteome analysis of rat liver mitochondria reveals a possible compensatory response to endotoxic shock. FEBS Lett 580:1257-62.

O2k-Abstracts

 PublishedReference
Kozlov 2013 Abstract MiP20132013Kozlov AV, Paier-Pourani J, Weidinger A, Dungel P, Redl H, Duvigneau C (2013) Regulatory role of mitochondrial ROS upon inflammation. Mitochondr Physiol Network 18.08.
Dungel 2013 Abstract MiP20132013Dungel P, Perlinger M, Faulhammer B, Weidinger A, Redl H, Kozlov AV (2013) Iron-mediated injury of mitochondria is attenuated by nitrite. Mitochondr Physiol Network 18.08.
Kozlov 2010 Abstract IOC602010Kozlov AV (2011) Mitochondrial response to shock stimuli in in vitro models. MiPNet15.10.