Rotenone: Difference between revisions

Revision as of 15:17, 15 September 2010

high-resolution terminology - matching measurements at high-resolution

Rotenone

Description

(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; Inhibitor of complex I via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI.

Abbreviation: Rot

Reference: MiPNet11.09, MiPNet09.12, MiPNet12.15

Labels:

Enzyme: Complex I

HRR: Chemicals; Media"Chemicals; Media" is not in the list (Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, O2k-Spectrophotometer, O2k-Manual, O2k-Protocol, ...) of allowed values for the "Instrument and method" property.

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-(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; Inhibitor of complex I via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI.
+{{MitoPedia
-==References==
+|abbr=Rot
-Gnaiger E, ed (2007) Mitochondrial Pathways and Respiratory Control. OROBOROS MiPNet Publications, Innsbruck: 96 pp.
+|description=(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; Inhibitor of [[complex I]] via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI.
+|info=MiPNet11.09, MiPNet09.12, MiPNet12.15
-{{#set:keyword=Chemical|keyword=Respiration}}
+|type=Inhibitor ETS
-{{MitoPedia}}
+}}
+{{Labeling
+|instruments=Chemicals; Media
+|discipline=Mitochondrial Physiology
+|kinetics=Inhibitor; Uncoupler
+|enzymes=Complex I
+}}