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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Gregg 2019 J Biol Chem	2019	Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ (2019) Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at Complex I in pancreatic β-cells. J Biol Chem 294:4656-66.	OXPHOS ET LEAK	N S NS ROX	Permeabilized tissue	Mouse	Islet cell;pancreas;thymus
Greggio 2017 Cell Metab	2017	Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, Cantó C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Grevengoed 2015 J Lipid Res	2015	Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82.	LEAK OXPHOS	F N NS ROX	Permeabilized tissue	Mouse	Heart Other cell lines HEK
Grewal 2020 Exp Neurol	2020	Grewal R, Reutzel M, Dilberger B, Hein H, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C, Eckert GP (2020) Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol 328:113248.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Neuroblastoma
Groeger 2010 Crit Care	2010	Groeger M, Wagner F, Baumgart K, Huber-Lang M, Knoeferl M, Georgieff M, Radermacher P, Szabo C, Calzia E (2010) Mitochondrial respiration and cytochrome c inhibition by sulfide in peritoneal macrophages in vitro: Effects of temperature and pH. Crit Care 14:P6.	ET	CIV NS	Permeabilized cells		Macrophage-derived
Groennebaek 2018 Front Physiol	2018	Groennebaek T, Jespersen NR, Jakobsgaard JE, Sieljacks P, Wang J, Rindom E, Musci RV, Bøtker HE, Hamilton KL, Miller BF, de Paoli FV, Vissing K (2018) Skeletal muscle mitochondrial protein synthesis and respiration increase with low-load blood flow restricted as well as high-load resistance training. Front Physiol 9:1796.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Groennebaek 2020 Cells	2020	Groennebaek T, Billeskov TB, Schytz CT, Jespersen NR, Bøtker HE, Olsen RKJ, Eldrup N, Nielsen J, Farup J, De Paoli FV, Vissing K (2020) Mitochondrial structure and function in the metabolic myopathy accompanying patients with critical limb ischemia. Cells 9:E570.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Grundmanova 2016 Physiol Res	2016	Grundmanová M, Jarkovská D, Süß A, Tůma Z, Marková M, Grundman Z, El-Kadi A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S601-9.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Guadalupe-Grau 2014 J Sports Sci	2014	Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2014) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 26:1-9.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Guadalupe-Grau 2015 J Sports Sci	2015	Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2015) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 33:570-8.	LEAK OXPHOS	F N NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
Guitart 2010 J Biol Chem	2010	Guitart T, Leon Bernardo T, Sagalés J, Stratmann T, Bernués J, Ribas de Pouplana L (2010) New aminoacyl-tRNA synthetase-like protein in insecta with an essential mitochondrial function. J Biol Chem 285:38157-66.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Drosophila Hexapods
Guo 2020 Hum Gene Ther	2020	Guo Y, Zhang K, Gao X, Zhou Z, Liu Z, Yang K, Huang K, Yang Q, Long Q (2020) Sustained oligomycin sensitivity conferring protein expression in cardiomyocytes protects against cardiac hypertrophy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Heart
Gupta 2021 Sci Rep	2021	Gupta MK, Sahu A, Sun Y, Mohan ML, Kumar A, Zalavadia A, Wang X, Martelli EE, Stenson K, Witherow CP, Drazba J, Dasarathy S, Naga Prasad SV (2021) Cardiac expression of microRNA-7 is associated with adverse cardiac remodeling. Sci Rep 11:22018.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Heart
Gururaja Rao 2019 Cells	2019	Gururaja Rao S, Bednarczyk P, Towheed A, Shah K, Karekar P, Ponnalagu D, Jensen HN, Addya S, Reyes BAS, Van Bockstaele EJ, Szewczyk A, Wallace DC, Singh H (2019) BK_Ca (Slo) channel regulates mitochondrial function and lifespan in Drosophila melanogaster. Cells 8:E945.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Drosophila
Gutman 1972 FEBS Lett	1972	Gutman M, Silman N (1972) Mutual inhibition between NADH oxidase and succinoxidase activities in respiring submitochondrial particles. FEBS Lett 26:207-10. doi: 10.1016/0014-5793(72)80574-x.		N S NS	SMP
Gvozdjakova 2019 Bratisl Lek Listy	2019	Gvozdjakova A, Sumbalova Z, Kucharska J, Chladekova A, Rausova Z, Vancova O, Komlosi M, Ulicna O, Mojto V (2019) Platelet mitochondrial bioenergetic analysis in patients with nephropathies and non-communicable diseases: a new method. Bratisl Lek Listy 120:630-35.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Platelet Blood cells
Gvozdjakova 2020 Diagnostics (Basel)	2020	Gvozdjáková A, Sumbalová Z, Kucharská J, Komlósi M, Rausová Z, Vančová O, Számošová M, Mojto V (2020) Platelet mitochondrial respiration, endogenous coenzyme Q₁₀ and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Platelet
Gvozdjakova 2021 PLoS One	2021	Gvozdjáková A, Sumbalová Z, Kucharská J, Szamosová M, Čápová L, Rausová Z, Vančová O, Mojto V, Langsjoen P, Palacka P (2021) Platelet mitochondrial respiration and coenzyme Q₁₀ could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases. PLoS ONE 16:e0256135.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Platelet
Gvozdjakova 2022 Environ Sci Pollut Res Int	2022	Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. https://doi.org/10.1007/s11356-022-22949-2	LEAK ROUTINE OXPHOS ET	N NS	Permeabilized cells Intact cells	Human	Platelet
Haberman 2019 Nat Commun	2019	Haberman Y, Karns R, Dexheimer PJ, Schirmer M, Somekh J, Jurickova I, Braun T, Novak E, Bauman L, Collins MH, Mo A, Rosen MJ, Bonkowski E, Gotman N, Marquis A, Nistel M, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Boyle BM, Mack DR, Baldassano RN, Shah S, Leleiko NS, Heyman MB, Grifiths AM, Patel AS, Noe JD, Aronow BJ, Kugathasan S, Walters TD, Gibson G, Thomas SD, Mollen K, Shen-Orr S, Huttenhower C, Xavier RJ, Hyams JS, Denson LA (2019) Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nat Commun 10:38.	OXPHOS ET	N S NS	Homogenate	Human	Endothelial;epithelial;mesothelial cell
Hadanny 2022 Sports Med Open	2022	Hadanny A, Hachmo Y, Rozali D, Catalogna M, Yaakobi E, Sova M, Gattegno H, Abu Hamed R, Lang E, Polak N, Friedman M, Finci S, Zemel Y, Bechor Y, Gal N, Efrati S (2022) Effects of hyperbaric oxygen therapy on mitochondrial respiration and physical performance in middle-aged athletes: a blinded, randomized controlled trial.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Hadjihambi 2022 J Hepatol	2022	Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox J, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L (2022) Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction. https://doi.org/10.1016/j.jhep.2022.08.008	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Nervous system
Haegler 2015 Toxicology	2015	Haegler P, Grünig D, Berger B, Krähenbühl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58.	OXPHOS	N S CIV NS		Human	Liver Other cell lines
Hafen 2018 J Appl Physiol (1985)	2018	Hafen PS, Preece CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol (1985) 125:1447-55.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Hafen 2019 J Appl Physiol (1985)	2019	Hafen PS, Abbott K, Bowden JA, Lopiano R, Hancock CR, Hyldahl RD (2019) Daily heat treatment maintains mitochondrial function and attenuates atrophy in human skeletal muscle subjected to immobilization. J Appl Physiol (1985) 127:47-57. https://doi.org/10.1152/japplphysiol.01098.2018	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Hagl 2013 Pharmacol Res	2013	Hagl S, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP (2013) Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res 76C:17-27.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Guinea pig	Nervous system
Hagl 2014 J Alzheimers Dis b	2014	Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Hagl 2015 J Alzheimers Dis	2015	Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Kidney Other cell lines
Hagl 2015 Molecules	2015	Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Other cell lines
Hagl 2016 Neuromolecular Med	2016	Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Hagl 2016 Nutr Neurosci	2016	Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Halbach 2019 Am J Physiol Regul Integr Comp Physiol	2019	Halbach JL, Prieto JM, Wang AW, Hawisher D, Cauvi DM, Reyes T, Okerblom J, Ramirez-Sanchez I, Villarreal F, Patel HH, Bickler SW, Perdrizet GA, De Maio A (2019) Early hyperbaric oxygen therapy improves survival in a model of severe sepsis. Am J Physiol Regul Integr Comp Physiol 317:R160-R168.	LEAK OXPHOS	N NS	Intact cells	Mouse	Liver
Halle 2019 Am J Physiol Regul Integr Comp Physiol	2019	Halle JL, Pena GS, Paez HG, Castro AJ, Rossiter HB, Visavadiya NP, Whitehurst MA, Khamoui AV (2019) Tissue-specific dysregulation of mitochondrial respiratory capacity and coupling control in colon-26 tumor-induced cachexia. Am J Physiol Regul Integr Comp Physiol 317:R68-R82.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue Intact cells	Mouse	Skeletal muscle Liver Fat
Halling 2019 Am J Physiol Endocrinol Metab	2019	Halling JF, Jessen H, Nøhr-Meldgaard J, Thiellesen Buch B, Masselkhi Christensen N, Gudiksen A, Ringholm S, Neufer PD, Prats C, Pilegaard H (2019) PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training. Am J Physiol Endocrinol Metab 317:E513-E525.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Hals 2015 PLoS One	2015	Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus Other cell lines
Hamilton 2016 Am J Physiol Heart Circ Physiol	2016	Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80.	LEAK OXPHOS	F N S NS Other combinations ROX	Permeabilized tissue Isolated mitochondria	Mouse	Heart
Hamilton 2016 Physiol Rep	2016	Hamilton DJ, Minze LJ, Kumar T, Cao TN, Lyon CJ, Geiger PC, Hsueh WA, Gupte AA (2016) Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice. Physiol Rep 4. pii: e12913.	LEAK OXPHOS	F N NS	Isolated mitochondria	Mouse	Heart
Hamm 2021 Mol Ther Methods Clin Dev	2021	Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW (2023) Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice. https://doi.org/10.1016/j.omtm.2021.02.024	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Han 2017 Abstract IOC122		Retinal mitochondria respiration defects precede hyperglycemia onset in type 2 diabetes.	OXPHOS	NS	Homogenate	Rat	Nervous system
Han 2017 Invest Ophthalmol Vis Sci	2017	Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest Ophthalmol Vis Sci 58:3826-39.	LEAK OXPHOS	N S CIV NS ROX	Homogenate	Rat	Nervous system
Han 2017 MiP2017		Metabolic syndrome differentially impacts the retina and underlying retinal pigment epithelium cells.	LEAK OXPHOS	S CIV NS		Rat	Nervous system
Hancock 2018 Elife	2018	Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Heart
Hand 2012 Abstract Bioblast		Patil Y, Gnaiger E, Hand SC (2012) Respiration in embryo lysates reveals diminished Complex I activity and inhibition of the phosphorylation system during diapause in Artemia franciscana. Mitochondr Physiol Network 17.12.	OXPHOS ET	N S NS	Homogenate	Artemia Crustaceans
Hansen 2015 Obesity (Silver Spring)	2015	Hansen M, Lund MT, Gregers E, Kraunsøe R, Van Hall G, Helge JW, Dela F (2015) Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB. Obesity (Silver Spring) 23:2022-9.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Fat
Hansen 2015 Shock	2015	Hansen ME, Simmons KJ, Tippetts TS, Thatcher MO, Saito RR, Hubbard ST, Trumbull AM, Parker BA, Taylor OJ, Bikman BT (2015) Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism. Shock 44:585-92.	OXPHOS LEAK ET	N NS ROX	Permeabilized cells Permeabilized tissue	Mouse	Skeletal muscle Other cell lines
Hansen 2021 Physiol Rep	2021	Hansen C, Olsen K, Pilegaard H, Bangsbo J, Gliemann L, Hellsten Y (2021) High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells. Physiol Rep 9:e14855.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Rat	Skeletal muscle Endothelial;epithelial;mesothelial cell
Hansen 2022 Free Radic Biol Med	2022	Hansen C, Møller S, Ehlers T, Wickham KA, Bangsbo J, Gliemann L, Hellsten Y (2022) Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training. https://doi.org/10.1016/j.freeradbiomed.2021.12.265	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell
Hansen 2022 Magn Reson Med	2022	Hansen K, Hansen ESS, Jespersen NRV, Bøtker HE, Pedersen M, Wang T, Laustsen C (2022) Hyperpolarized ¹³C MRI reveals large changes in pyruvate metabolism during digestion in snakes. https://doi.org/10.1002/mrm.29239	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Reptiles	Liver
Hanssen 2015 Diabetes	2015	Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes 65:1179-89.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Hanssen 2015 Nat Med	2015	Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P (2015) Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nat Med 21:863-5.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle

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