User talk:Beno Marija/MitO2 Kit Produktseite: Difference between revisions
Beno Marija (talk | contribs) (Created page with "{{Product |description= Cell permeable compound - MitO2-Kit, 2 vials; for a final volume of 35 mg (25mg NVP118 + 10mg NVP161) |product id= (##) |product type=O2k |info=NVP11...") Β |
Beno Marija (talk | contribs) No edit summary |
||
Line 28: | Line 28: | ||
:::: The MitO2-Kit is composed of equal quantities of the following Compounds: | :::: The MitO2-Kit is composed of equal quantities of the following Compounds: | ||
::::* '''NVP118''' | ::::* '''[[NVP118]]''' | ||
::::: Description: Succinate prodrug: C<sub>10</sub>H<sub>14</sub>O<sub>8</sub>, Molecular weight 262,2g.mol<sup>-1</sup> | ::::: Description: Succinate prodrug: C<sub>10</sub>H<sub>14</sub>O<sub>8</sub>, Molecular weight 262,2g.mol<sup>-1</sup> | ||
::::: Aliquots per 25 mg | ::::: Aliquots per 25 mg | ||
::::* '''NVP161''' | ::::* '''[[NVP161]]''' | ||
::::: Description: Malonate prodrug: C<sub>9</sub>H<sub>12</sub>O<sub>8</sub>, Molecular weight 248,2g.mol<sup>-1</sup> | ::::: Description: Malonate prodrug: C<sub>9</sub>H<sub>12</sub>O<sub>8</sub>, Molecular weight 248,2g.mol<sup>-1</sup> |
Revision as of 16:44, 22 February 2019
User talk:Beno Marija/MitO2 Kit Produktseite
Description | Cell permeable compound - MitO2-Kit, 2 vials; for a final volume of 35 mg (25mg NVP118 + 10mg NVP161) |
---|---|
Product ID | (##) |
Type | O2k |
Link | NVP118, NVP161 |
Image |
Compounds
Cell permeable compound - MitO2-Kit
Cell permeable compound - MitO2-Kit. |
Β» Β» Versions
Oroboros (2019-03-01) Mitochondr Physiol Network
Abstract: Gnaiger E, Laner V, Passrugger M, NeuroVive Pharmaceutical AB (2019) cell permeable compound - MitO2-Kit. Mitochondr Physiol Network 24.03(01):1-2.
(##) The cell permeable compound MitO2-Kit is the first generation of NeuroVive Pharmaceutical AB's succinate/malonate prodrugs and was developed to stimulate and inhibit Complex II of the respiratory electron transfer system in intact cells, and will expand the toolbox for evaluating the role of mitochondria in disease.
- Β» Product: Oroboros O2k, O2k-Catalogue
β’ Keywords: Mit02-Kit
β’ O2k-Network Lab: AT_Innsbruck_Oroboros, NeuroVive
Compounds of MitO2-Kit
- The MitO2-Kit is composed of equal quantities of the following Compounds:
-
- Description: Succinate prodrug: C10H14O8, Molecular weight 262,2g.mol-1
- Aliquots per 25 mg
-
- Description: Malonate prodrug: C9H12O8, Molecular weight 248,2g.mol-1
- Aliquots per 10 mg
- Reference:
- Ehinger JK, Piel S, Ford R, Karlsson M, SjΓΆvall F, Frostner EΓ , Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, ElmΓ©r E (2016) Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency. Nat Commun 7:12317. Β»Bioblast linkΒ« - Original publication introducing MitO2.
Expiry date of MitO2
- The stability of compounds in DMSO solution at room temperature is for at least 24h. The estimated stability of the compounds in DMSO at -20 would be weeks. The aliquoted 118 and 161 are stable at -20 for 6 months+. The powder is likely stable for much longer.
- CAS-Number 1592635-33-0 for NV-118
- CAS-Number 1432752-62-9 for NV-161
Labels: MiParea: Instruments;methods
HRR: O2k-Protocol
O2k-chemicals and media