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• NS-N pathway control efficiency
  ...f a mathematical addition when calculating the sum of CI- plus CII-linked respiration measured separately.
  2 KB (229 words) - 18:28, 1 January 2021
• N/NS pathway control ratio
  ...NS-pathway control state]] (N in combination with succinate). NS indicates respiration with a cocktail of substrates supporting the N- and S-pathways.
  1 KB (163 words) - 18:27, 1 January 2021
• NS e-input
  ...in the absence of succinate prevents a significant stimulation of S-linked respiration. For more details, see: [[Additive effect of convergent electron flow]].
  1 KB (149 words) - 18:49, 1 January 2021
• Diaz 2023 Front Mol Biosci
  ...es with lower CI-linked respiration which is compensated by increasing CII respiration. PL bioenergetics phenotypes in children associate with whole-body metaboli |area=Respiration, Exercise physiology;nutrition;life style
  3 KB (384 words) - 15:17, 5 October 2023
• NADH electron transfer-pathway state
  ...depletion into the incubation medium. The residual involvement of S-linked respiration in the N-pathway control state can be further suppressed by the CII-inhibit ::::With N-substrates, LEAK respiration ''L''.
  3 KB (409 words) - 08:06, 25 November 2023
• Burtscher 2015 Mitochondrion
  ...ial density and suggest flux control ratios as a valid method to normalize respiration to mitochondrial density. ...kainate, there was a down-regulation of CI- and upregulation of CII-linked respiration in the resulting epileptic ipsilateral hippocampus compared to the contrala
  3 KB (405 words) - 12:58, 27 December 2021
• Burtscher 2014 Abstract MiP2014
  |title=Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain. ...ependently, Complex I-, II- and IV-linked (CI, CII, and CIV, respectively) respiration, as well as the combined CI&II-linked OXPHOS- and electron transfer-pathway
  3 KB (408 words) - 18:29, 10 January 2022
• Elliehausen 2021 Exp Gerontol
  ...CJ, Minton DM, Nichol AD, Konopka AR (2021) Skeletal muscle mitochondrial respiration in a model of age-related osteoarthritis is impaired after dietary rapamyci ...d OA. Collectively, our data suggest that Rap with or without Met inhibits CI-linked capacity and increases ADP sensitivity in DH guinea pigs that have greater
  2 KB (354 words) - 12:57, 19 September 2022
• Sumbalova 2014 Abstract MiP2014
  ...piration, inhibits CII-linked (succinate+rotenone; coupled and noncoupled) respiration at 2 mM concentration. Mutual interference between succinate and malate was ...as determined by inhibition of SDH with 5 mM malonate after ADP-stimulated respiration with pyruvate&glutamate&malate, amounted to more than 50 % without malate,
  4 KB (587 words) - 13:46, 5 January 2023
• Burtscher J 2016 Abstract MitoFit Science Camp 2016
  ...ween motor cortex, striatum, hippocampus and pons of naïve mice. CI-linked respiration was highest in motor cortex. In contrast, CII-linked capacity was especiall ...els, but was elevated when normalized to ET-capacity. Tissue-mass specific CI-linked oxygen consumption and ET-capacity remained decreased.
  3 KB (364 words) - 18:45, 10 January 2022
• Reverse electron flow from CII to CI
  ...re respiring using [[Glycerophosphate |Gp]] without rotenone in the [[LEAK respiration|LEAK]] state. Addition of I_Q-side inhibitors (ubiquinone-binding |type=Respiration
  2 KB (211 words) - 12:20, 25 November 2020
• Sumbalova 2011 Abstract Kagoshima
  ...CI+II electron supply increased JH2O2 further in the passive LEAK state of respiration. The upper limit of respiratory capacity and the scope of ROS signalling, t |area=Respiration, Instruments;methods
  3 KB (457 words) - 18:18, 10 January 2022
• Wagenaars 2014 Abstract IOC 2014-04 Schroecken
  ...with a mild isolated CI deficiency. To stimulate mitochondrial ATP-linked respiration, cells were treated with the hormone bradykinin during O2 consumption measu |area=Respiration
  3 KB (352 words) - 15:46, 9 November 2016
• S/NS pathway control ratio
  ...s the [[background state]] does not provide a valid estimation of S-linked respiration with succinate in the absence of Rot, since [[oxaloacetate]] accumulates as
  1 KB (163 words) - 18:28, 1 January 2021
• Thomsen 2017 Neurobiol Aging
  ...neity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24. ...to middle-aged mice (13-14 months), we found that complex I-linked state 3 respiration (CI) was reduced at middle age in CSB^m/m hippocampus, but not in
  2 KB (334 words) - 17:33, 25 February 2020
• Schoepf 2016 Abstract Androgens 2016
  ...Complex I components strongly correlated with a relative loss of CI-linked respiration in both CA and BE tissue. No statistically significant correlation of mt-mu |area=Respiration, mtDNA;mt-genetics, Patients
  3 KB (356 words) - 18:40, 10 January 2022
• Bouitbir 2022 Int J Mol Sci
  ...ers, acute exposure to imatinib and sorafenib decreased CI- and CIV-linked respiration in the presence of the drugs. Electron microscopy showed enlarged mitochond |area=Respiration, Pharmacology;toxicology
  3 KB (381 words) - 11:24, 20 February 2022
• GMS-pathway control state
  ...on (two versus three coupling sites), the CI/CI&II ratio is lower for LEAK respiration (0.3 to 0.4; Garait et al 2005) compared to OXPHOS capacity. ...d by the high FCCP concentration applied (10 µM) which is known to inhibit respiration (Steinlechner-Maran et al 1996). In mouse skeletal muscle, however, the P/E
  3 KB (378 words) - 18:30, 17 March 2022
• Jang 2016 Clin Toxicol (Phila)
  ...Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. C |abstract=The objective of this study is to measure mitochondrial respiration using intact cells from whole blood exposed to cyanide as a new biomarker f
  3 KB (419 words) - 23:25, 29 February 2020
• Sumbalova 2016a Abstract MitoFit Science Camp 2016
  ...nt. Nevertheless, there are some inherent limitations to this approach: a) CI-linked respiratory activity cannot be totally isolated from that of CII, unless CI ...fuel CI-linked respiration, inhibits both coupled and uncoupled CII-linked respiration [4].
  7 KB (1,014 words) - 19:16, 10 January 2022

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