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 YearReferenceTissue and cellCell lineMammal and modelNonmammal
MiPNet18.10 O2k-Specifications2024-03-26
Oroboros

O2k-specifications for respirometry and comprehensive OXPHOS analysis.

FibroblastHuman
Nastasi 2024 Int J Mol Sci2024Nastasi MR, Borisov VB, Forte E (2024) Membrane-bound redox enzyme cytochrome bd-I promotes carbon monoxide-resistant Escherichia coli growth and respiration. https://doi.org/10.3390/ijms25021277
Taylor 2024 Pilot Feasibility Stud2024Taylor MK, Burns JM, Choi IY, Herda TJ, Lee P, Smith AN, Sullivan DK, Swerdlow RH, Wilkins HM (2024) Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease. Pilot Feasibility Stud 10:42. https://doi.org/10.1186/s40814-024-01469-5Lymphocyte
Platelet		Human
Song 2024 Commun Biol2024Song A, Zhao N, Hilpert DC, Perry C, Baur JA, Wallace DC, Schaefer PM (2024) Visualizing subcellular changes in the NAD(H) pool size versus redox state using fluorescence lifetime imaging microscopy of NADH. Commun Biol 7:428. https://doi.org/10.1038/s42003-024-06123-7HEKHuman
Donnelly 2024 Redox Biol2024Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion A-C, Matera A, Tavernari D, Campiche O, Paolicelli RC, Zanou N, Kayser B, Gnaiger E, Place N (2024) Functional hypoxia reduces mitochondrial calcium uptake. Redox Biol 71:103037. https://doi.org/10.1016/j.redox.2024.103037Heart
Skeletal muscle		Human
Mouse
Natsui 2024 Physiol Rep2024Natsui H, Watanabe M, Yokota T, Tsuneta S, Fumoto Y, Handa H, Shouji M, Koya J, Nishino K, Tatsuta D, Koizumi T, Kadosaka T, Nakao M, Koya T, Temma T, Ito YM, Kanako HC, Hatanaka Y, Yasushige S, Wakasa S, Miura S, Masuda T, Nishioka N, Naraoka S, Ochi K, Kudo T, Ishikawa T, Anzai T (2024) Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery. Physiol Rep 12:e15957. https://doi.org/10.14814/phy2.15957FatHuman
Al-Sabri 2024 Sci Rep2024Al-Sabri MH, Ammar N, Korzh S, Alsehli AM, Hosseini K, Fredriksson R, Mwinyi J, Williams MJ, Boukhatmi H, Schiöth HB (2024) Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes. https://doi.org/10.1038/s41598-024-53446-wSkeletal muscleDrosophila
Lin 2024 Apoptosis2024Lin HY, Liang CJ, Yang MY, Chen PL, Wang TM, Chen YH, Shih YH, Liu W, Chiu CC, Chiang CK, Lin CS, Lin HC (2024) Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury. https://doi.org/10.1007/s10495-023-01897-3KidneyHuman
Kim 2024 J Exerc Rehabil2024Kim TW, Park SS, Kim SH, Kim MK, Shin MS, Kim SH (2024) Exercise before pregnancy exerts protective effect on prenatal stress-induced impairment of memory, neurogenesis, and mitochondrial function in offspring. J Exerc Rehabil 20:2-10. https://doi.org/10.12965/jer.2448068.034Nervous systemMouse
Mahapatra 2024 J Gerontol A Biol Sci Med Sci2024Mahapatra G, Gao Z, Bateman JR 3rd, Lockhart SN, Bergstrom J, Piloso JE, Craft S, Molina AJA (2024) Peripheral blood cells from older adults exhibit sex-associated differences in mitochondrial function. J Gerontol A Biol Sci Med Sci [Epub ahead of print]. https://doi.org/10.1093/gerona/glae098Blood cellsHuman
Abegg 2024 Toxicol Lett2024Abegg VF, Panajatovic MV, Mancuso RV, Allard JA, Duthaler U, Odermatt A, Krähenbühl S, Bouitbir J (2024) Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. https://doi.org/10.1016/j.toxlet.2024.01.008LiverHuman
Cefis 2024 Acta Physiol (Oxf)2024Cefis M, Dargegen M, Marcangeli V, Taherkhani S, Dulac M, Leduc-Gaudet JP, Mayaki D, Hussain SNA, Gouspillou G (2024) MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission. Acta Physiol (Oxf) [Epub ahead of print]. https://doi.org/10.1111/apha.14119Skeletal muscleMouse
Meldau 2024 Mol Genet Metab Rep2024Meldau S, Ackermann S, Riordan G, van der Watt GF, Spencer C, Raga S, Khan K, Blackhurst DM, van der Westhuizen FH (2024) A novel mitochondrial DNA variant in MT-ND6: m.14430A>C p.(Trp82Gly) identified in a patient with Leigh syndrome and complex I deficiency. Mol Genet Metab Rep 39:101078. https://doi.org/10.1016/j.ymgmr.2024.101078FibroblastHuman
Opperdoes 2024 BMC Genomics2024Opperdoes FR, Záhonová K, Škodová-Sveráková I, Bučková B, Chmelová Ľ, Lukeš J, Yurchenko V (2024) In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code. BMC Genomics 25:184. https://doi.org/10.1186/s12864-024-10094-8Protists
Pegoraro 2024 Adv Drug Deliv Rev2024Pegoraro C, Domingo I, Conejos-Sánchez I, Vicent MJ (2024) Unlocking the mitochondria for nanomedicine-based treatments: overcoming biological barriers, improving designs, and selecting verification techniques.
Patil 2024 J Exp Biol2024Patil YN, Gnaiger E, Landry AP, Leno ZJ, Hand SC (2024) OXPHOS capacity is diminished and the phosphorylation system inhibited during diapause in an extremophile, embryos of Artemia franciscana. J Exp Biol 227:jeb.245828. https://doi.org/10.1242/jeb.245828Artemia
Romagnolo 2024 Acta Neuropathol2024Romagnolo A, Dematteis G, Scheper M, Luinenburg MJ, Mühlebner A, Van Hecke W, Manfredi M, De Giorgis V, Reano S, Filigheddu N, Bortolotto V, Tapella L, Anink JJ, François L, Dedeurwaerdere S, Mills JD, Genazzani AA, Lim D, Aronica E (2024) Astroglial calcium signaling and homeostasis in tuberous sclerosis complex. Acta Neuropathol 147:48. https://doi.org/10.1007/s00401-024-02711-3Nervous systemHuman
Hu 2024 Front Endocrinol (Lausanne)2024Hu Y, Fang B, Tian X, Wang H, Tian X, Yu F, Li T, Yang Z, Shi R (2024) Passive exercise is an effective alternative to HRT for restoring OVX induced mitochondrial dysfunction in skeletal muscle. Front Endocrinol (Lausanne) 15:1356312. https://doi.org/10.3389/fendo.2024.1356312Skeletal muscleMouse
Qiao 2024 J Sport Health Sci2024Qiao YS, Blackwell TL, Cawthon PM, Coen PM, Cummings SR, Distefano G, Farsijani S, Forman DE, Goodpaster BH, Kritchevsky SB, Mau T, Toledo FGS, Newman AB, Glynn NW (2024) Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics: The Study of Muscle, Mobility and Aging (SOMMA). https://doi.org/10.1016/j.jshs.2024.02.001Skeletal muscleHuman
Tsouka 2024 Commun Med (Lond)2024Tsouka S, Kumar P, Seubnooch P, Freiburghaus K, St-Pierre M, Dufour JF, Masoodi M (2024) Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human. Commun Med (Lond) 4:39. https://doi.org/10.1038/s43856-024-00465-3LiverMouse
Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis2024Balmaceda V, Komlodi T, Szibor M, Gnaiger E, Moore AL, Fernandez-Vizarra E, Viscomi C (2024) The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease. Biochim Biophys Acta Mol Basis Dis 1870:167033. https://doi.org/10.1016/j.bbadis.2024.167033Nervous system
Liver		Mouse
Torcasio 2024 J Transl Med2024Torcasio R, Gallo Cantafio ME, Veneziano C, De Marco C, Ganino L, Valentino I, Occhiuzzi MA, Perrotta ID, Mancuso T, Conforti F, Rizzuti B, Martino EA, Gentile M, Neri A, Viglietto G, Grande F, Amodio N (2024) Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity. J Transl Med 22:208. https://doi.org/10.1186/s12967-024-05013-0Blood cellsHuman
Queiroz 2024 Ecotoxicol Environ Saf2024Queiroz MIC, Lazaro CM, Dos Santos LMB, Rentz T, Virgilio-da-Silva JV, Moraes-Vieira PMM, Cunha FAS, Santos JCC, Vercesi AE, Leite ACR, Oliveira HCF (2024) In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice. Ecotoxicol Environ Saf 275:116254. https://doi.org/10.1016/j.ecoenv.2024.116254LiverMouse
Dong 2024 Nat Commun2024Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H (2024) Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease. https://doi.org/10.1038/s41467-023-44057-6LiverMouse
Xiao 2024 Sci Adv2024Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z (2024) AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise. Sci Adv 10:eadj2752. https://doi.org/10.1126/sciadv.adj2752Skeletal muscleMouse
Shi 2024 Clin Sci (Lond)2024Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z (2024) Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning. Clin Sci (Lond) 138:371-85. https://doi.org/10.1042/cs20230973FibroblastMouse
Fitzgerald 2024 J Cachexia Sarcopenia Muscle2024Fitzgerald LF, Lackey J, Moussa A, Shah SV, Castellanos AM, Khan S, Schonk M, Thome T, Salyers ZR, Jakkidi N, Kim K, Yang Q, Hepple RT, Ryan TE (2024) Chronic aryl hydrocarbon receptor activity impairs muscle mitochondrial function with tobacco smoking. https://doi.org/10.1002/jcsm.13439Skeletal muscleMouse
Ravasz 2024 Sci Rep2024Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, Marzullo BP, Tennant DA, Greenwood B, Kitayev A, Hill C, Komlódi T, Doerrier C, Cunatova K, Fernandez-Vizarra E, Gnaiger E, Kiebish Michael A, Raska A, Kolev K, Czumbel B, Narain NR, Seyfried TN, Chinopoulos C (2024) Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia. Sci Rep 14:1729. https://doi.org/10.1038/s41598-024-51365-4Heart
Liver		Mouse
Visker 2024 Exp Physiol2024Visker JR, Leszczynski EC, Wellette-Hunsucker AG, McPeek AC, Quinn MA, Kim SH, Bazil JN, Ferguson DP (2024) Postnatal growth restriction alters myocardial mitochondrial energetics in mice. https://doi.org/10.1113/ep091304HeartMouse
Meszaros 2024 Transpl Int2024Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. Transpl Int 37. https://doi.org/10.3389/ti.2024.12380LiverHuman
Hunter-Manseau 2024 Insect Sci2024Hunter-Manseau F, Cormier SB, Strang R, Pichaud N (2024) Fasting as a precursor to high-fat diet enhances mitochondrial resilience in Drosophila melanogaster. Insect Sci [Epub ahead of print]. https://doi.org/10.1111/1744-7917.13355Drosophila
Fehsenfeld 2024 Comp Biochem Physiol A Mol Integr Physiol2024Fehsenfeld S, Yoon GR, Quijada-Rodriguez AR, Kandachi-Toujas H, Calosi P, Breton S, Weihrauch D (2024) Short-term exposure to high pCO2 leads to decreased branchial cytochrome C oxidase activity in the presence of octopamine in a decapod. https://doi.org/10.1016/j.cbpa.2024.111603
MiPNet14.06 Instrumental O2 background2023-10-19
O2k-Manual

O2k Quality Control 2: Instrumental oxygen background correction and accuracy of oxygen flux.

MiPNet28.08 Oroboros O2k Series J manual2023-10-19
O2k-Manual

Oroboros O2k Series J manual

MiPNet28.07 NextGen-O2k Series XB manual2023-10-19
O2k-Manual

NextGen-O2k Series XB manual

MiPNet28.10 SmartPOS-service2023-09-29
O2k-Manual

SmartPOS: Service

MiPNet19.14 SOP Hamilton microsyringes2023-09-28
O2k-Manual

SOP for manual O2k-titrations with Hamilton microsyringes.

MiPNet28.09 O2k-Fluo Smart-Module manual2023-09-25
O2k-Manual

O2k-Fluo Smart-Module manual

MiPNet28.06 IOC161 Coimbra PT2023-04-12
O2k-Network

Cantanhede, PT, 2023 Apr 12. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC161.

MiPNet19.03 O2k-cleaning and ISS2023-03-14
O2k-Manual

O2k-Chamber cleaning SOP and Integrated Suction System (ISS).

MiPNet22.11 O2k-FluoRespirometer manual2023-03-14
O2k-Manual

O2k-FluoRespirometer manual.

MiPNet28.03 IOC157 Los Angeles US2023-02-14
O2k-Network

Los Angeles, CA US, 2023 Feb 14-16. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC157.

MiPNet06.03 POS-calibration-SOP2023-02-06
O2k-Manual

O2k Quality Control 1: Polarographic oxygen sensors and accuracy of calibration.

Bowering 2023 Front Physiol2023Bowering LR, McArley TJ, Devaux JBL, Hickey AJR, Herbert NA (2023) Metabolic resilience of the Australasian snapper (Chrysophrys auratus) to marine heatwaves and hypoxia. https://doi.org/10.3389/fphys.2023.1215442HeartFishes
Wang 2023 Cancer Cell Int2023Wang Y, Wang J, Chen L, Chen Z, Wang T, Xiong S, Zhou T, Wu G, He L, Cao J, Liu M, Li H, Gu H (2023) PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis. https://doi.org/10.1186/s12935-023-03178-0Endothelial;epithelial;mesothelial cellHuman
Kim 2023 bioRxiv2023Kim Y, Li C, Gu C, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Fang Y, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy. https://doi.org/10.1101/2023.01.10.523171Endothelial;epithelial;mesothelial cellMouse
Kienzle 2023 BMC Biol2023Kienzle L, Bettinazzi S, Choquette T, Brunet M, Khorami HH, Jacques JF, Moreau M, Roucou X, Landry CR, Angers A, Breton S (2023) A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. https://doi.org/10.1186/s12915-023-01609-yHEK
HeLa		Human
Morales-Rubio 2023 Sci Rep2023Morales-Rubio R, Bernal-Ramírez J, Rubio-Infante N, Luévano-Martínez LA, Ríos A, Escalante BA, García-Rivas G, Rodríguez González J (2023) Cellular shortening and calcium dynamics are improved by noisy stimulus in a model of cardiomyopathy. https://doi.org/10.1038/s41598-023-41611-6HeartMouse
Pacheco-Fuentes 2023 Oecologia2023Pacheco-Fuentes H, Ton R, Griffith SC (2023) Short- and long-term consequences of heat exposure on mitochondrial metabolism in zebra finches (Taeniopygia castanotis). https://doi.org/10.1007/s00442-023-05344-7Blood cellsBirds
Gonnot 2023 Nat Commun2023Gonnot F, Boulogne L, Brun C, Dia M, Gouriou Y, Bidaux G, Chouabe C, Crola Da Silva C, Ducreux S, Pillot B, Kaczmarczyk A, Leon C, Chanon S, Perret C, Sciandra F, Dargar T, Gache V, Farhat F, Sebbag L, Bochaton T, Thibault H, Ovize M, Paillard M, Gomez L (2023) SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases. https://doi.org/10.1038/s41467-023-39027-xHeartMouse
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