O2k-Publications: Permeabilized tissue

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O2k-Publications: Permeabilized tissue

O2k-Publications in the MiPMap

445 O2k-Publications on permeabilized tissue, including permeabilized muscle fibres: selective mechanical and chemical (saponin) permeabilization of the plasma membrane.

» For other mitochondrial preparations, see mt-preparations.

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Was published in year Has title Tissue and cell Cell line Mammal and model Nonmammal
MiPNet21.06 SUIT reference protocol 2016-01-23
O2k-Protocols
SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Bernardo 2015 J Nutr Biochem 2016 Bernardo AF, Cortez E, Neves FA, Vieira AKG, Soares V, Rodrigues-Cunha AC, Andrade DC, Thole AA, Gabriel-Costa D, Brum PC, Moura AS, Garcia-Souza EP (2015) Overnutrition during lactation leads to impairment in insulin signaling, upregulation of GLUT1 and increased mitochondrial carbohydrate oxidation in heart of weaned mice. J Nutr Biochem 29:124-32. Heart Mouse
Sirsat 2016 J Comp Physiol B 2016 Sirsat SK, Sirsat TS, Crossley JL, Sotherland PR, Dzialowski EM (2016) The 12-day thermoregulatory metamorphosis of Red-winged Blackbirds (Agelaius phoeniceus). J Comp Physiol B [Epub ahead of print]. Skeletal muscle Birds
Gemmink 2016 Diabetologia 2016 Gemmink A, Bosma M, Kuijpers HJ, Hoeks J, Schaart G, van Zandvoort MA, Schrauwen P, Hesselink MK (2016) Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia 59:1040-8. Skeletal muscle Human
Hamilton 2016 Am J Physiol Heart Circ Physiol 2016 Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. Heart Mouse
Volt 2016 J Pineal Res 2016 Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205. Heart Mouse
Sparks 2016 Diabetologia 2016 Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9. Skeletal muscle Other cell lines Human
Mouse
Rat
Sirsat 2016 Biol Open 2016 Sirsat SK, Sirsat TS, Price ER, Dzialowski EM (2016) Post-hatching development of mitochondrial function, organ mass and metabolic rate in two ectotherms, the American alligator (Alligator mississippiensis) and the common snapping turtle (Chelydra serpentina). Biol Open [Epub ahead of print]. Heart
Skeletal muscle
Reptiles
Cannon 2016 Lung 2016 Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8. Lung;gill Rat
Pamenter 2016 Biol Lett 2016 Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797. Nervous system Reptiles
Krischek 2016 Mol Reprod Dev 2016 Krischek C, Janisch S, Naraballobh W, Brunner R, Wimmers K, Wicke M (2016) Altered incubation temperatures between embryonic Days 7 and 13 influence the weights and the mitochondrial respiratory and enzyme activities in breast and leg muscles of broiler embryos. Mol Reprod Dev 83:71-8. Skeletal muscle Chicken
Salin 2016 J Exp Biol 2016 Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol [Epub ahead of print]. Skeletal muscle
Liver
Fishes
Farsijani 2016 J Clin Invest 2016 Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37. Nervous system Mouse
Cacabelos 2016 Acta Neuropathol Commun 2016 Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. Nervous system Other cell lines Mouse
Schoepf 2016 FEBS J 2016 Schoepf B, Schaefer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. FEBS J [Epub ahead of print]. Endothelial;epithelial;mesothelial cell
Genital
Fibroblast
Other cell lines
Human
Shama 2016 Evol Appl 2016 Shama LNS, Mark FC, Strobel A, Lokmer A, John U, Wegner KM (2016) Transgenerational effects persist down the maternal line in marine sticklebacks: gene expression matches physiology in a warming ocean. Evol Appl 10013/epic.47323. Heart Fishes
Jacobs 2016 J Physiol 2016 Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66. Skeletal muscle Human
Doerrier 2016 Mitochondrion 2016 Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. Heart Mouse
Magdalon 2016 Biochim Biophys Acta 2016 Magdalon J, Chimin P, Belchior T, Neves RX, Vieira-Lara MA, Andrade ML, Farias TS, Bolsoni-Lopes A, Paschoal VA, Yamashita AS, Kowaltowski AJ, Festuccia WT (2016) Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice. Biochim Biophys Acta 1861:430-8. Fat Mouse
Soendergaard 2016 Eur J Sport Sci 2016 Søndergård SD, Dela F, Helge JW, Larsen S (2016) Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci [Epub ahead of print]. Skeletal muscle Human
Boutant 2016 Cell Rep 2016 Boutant M, Kulkarni SS, Joffraud M, Raymond F, Métairon S, Descombes P, Cantó C (2016) SIRT1 gain of function does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75. Skeletal muscle
Liver
Fat
Mouse
Newell 2016 Physiol Entomol 2016 Newell C, Kane CL, Kane DC (2016) Mitochondrial substrate specificity in beetle flight muscle: assessing respiratory oxygen flux in small samples from Dermestes maculatus and Tenebrio molitor. Physiol Entomol p7. Skeletal muscle Hexapods
Wolff 2016 J Evol Biol 2016 Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47. Skeletal muscle Drosophila
Wang 2016 Toxicol Sci 2016 Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57. Endothelial;epithelial;mesothelial cell Fishes
MiPNet18.10 O2k versus multiwell 2015-10-05
OROBOROS
O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis.
Fibroblast Human
O2k versus multiwell respirometer 2015-05-21
Logo OROBOROS INSTRUMENTS.jpg
O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis.
Fibroblast Human
Guadalupe-Grau 2015 J Sports Sci 2015 Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2015) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 33:570-8. Skeletal muscle Human
Singh 2015 Free Radic Biol Med 2015 Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101. Heart Other cell lines Mouse
Kake-Guena 2015 J Exp Zool A Ecol Genet Physiol 2015 Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H1 (2015) Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry. J Exp Zool A Ecol Genet Physiol 323:292-300. Crustaceans
Cappel 2015 PLoS One 2015 Cappel DA, Lantier L, Palmisano BT, Wasserman DH, Stafford JM (2015) CETP expression protects female mice from obesity-induced decline in exercise capacity. PLoS One 10:e0136915. Skeletal muscle Mouse
Gariani 2015 Hepatology 2015 Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Siah Ku C, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2015) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204. Liver Mouse
Antoun 2015 JIMD Rep 2015 Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep [Epub ahead of print]. Skeletal muscle Human
Porter 2015 Burns 2015 Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics. Burns 42:112-22. Skeletal muscle Mouse
Dahl 2015 Acta Physiol (Oxf) 2015 Dahl R, Larsen S, Dohlmann TL, Qvortrup K, Helge JW, Dela F, Prats C (2015) Three dimensional reconstruction of the human skeletal muscle mitochondrial network as a tool to assess mitochondrial content and structural organization. Acta Physiol (Oxf) 213:145-55. Skeletal muscle Human
Diana 2015 Br J Surg 2015 Diana M, Agnus V, Halvax P, Liu YY, Dallemagne B, Schlagowski AI, Geny B, Diemunsch P, Lindner V, Marescaux J (2015) Intraoperative fluorescence-based enhanced reality laparoscopic real-time imaging to assess bowel perfusion at the anastomotic site in an experimental model. Br J Surg 102:e169-76. Endothelial;epithelial;mesothelial cell Pig
Porter 2015 Shock 2015 Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue. Shock 44:258-64. Fat Mouse
Cahill 2015 J Biol Chem 2015 Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19. Heart Mouse
Soares 2015 PLoS One 2015 Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600. Skeletal muscle Hexapods
Montero 2015 J Physiol 2015 Montero D, Cathomen A, Jacobs RA, Flück D, de Leur J, Keiser S, Bonne T, Kirk N, Lundby AK, Lundby C (2015) Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. J Physiol 593:4677-88. Skeletal muscle Human
Chekulayev 2015 Biochem Biophys Rep 2015 Chekulayev V, Mado K, Shevchuk I, Koit A, Kaldma A, Klepinin A, Timohhina N, Tepp K, Kandashvili M, Ounpuu L, Heck K, Truu L, Planken A, Valvere V, Kaambre T (2015) Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25. Endothelial;epithelial;mesothelial cell Human
Burtscher 2015 Mitochondrion 2015 Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12. Nervous system Mouse
Grevengoed 2015 J Lipid Res 2015 Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82. Heart HEK
Other cell lines
Mouse
Herbst 2015 Neuroscience 2015 Herbst EA, Holloway GP (2015) Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington's disease. Neuroscience 303:515-23. Nervous system Mouse
Porter 2015 Med Sci Sports Exerc 2015 Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31. Skeletal muscle Human
Diana 2015 Obes Surg 2015 Diana M, Pop R, Beaujeux R, Dallemagne B, Halvax P, Schlagowski I, Liu YY, Diemunsch P, Geny B, Lindner V, Marescaux J (2015) Embolization of arterial gastric supply in obesity (EMBARGO): an endovascular approach in the management of morbid obesity. proof of the concept in the porcine model.. Obes Surg 25:550-8. Endothelial;epithelial;mesothelial cell Pig
Ramos-Filho 2015 PLoS One 2015 Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766. Skeletal muscle Rat
Bowen 2015 Eur J Heart Fail 2015 Bowen TS, Rolim NP, Fischer T, Baekkerud FH, Medeiros A, Werner S, Brønstad E, Rognmo O, Mangner N, Linke A, Schuler G, Silva GJ, Wisløff U, Adams V (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail 17:263-72. Skeletal muscle Rat
Hasli 2015 Master Thesis 2015 Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147. Fishes
Larsen 2015 Physiol Rep 2015 Larsen S, Scheede-Bergdahl C, Whitesell T, Boushel R, Bergdahl A (2015) Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia. Physiol Rep 3 pii:e12467. Skeletal muscle Rat
Doerrier 2015 Thesis 2015 Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154. Heart
Liver
Mouse
Canto 2015 Curr Protoc Mouse Biol 2015 Cantó C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53. Heart
Skeletal muscle
Nervous system
Liver
Fat
Mouse
Woodlief 2015 J Breath Res 2015 Woodlief TL, Carnero EA, Standley RA, Distefano G, Anthony SJ, Dubis GS, Jakicic JM, Houmard JA, Coen PM, Goodpaster BH (2015) Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. J Breath Res 9:016009. Skeletal muscle Human
Porter 2015 Am J Physiol Endocrinol Metab 2015 Porter C, Hurren NM, Cotter MV, Bhattarai N, Reidy PT, Dillon EL, Durham WJ, Tuvdendorj D, Sheffield-Moore M, Volpi E, Sidossis LS, Rasmussen BB, Børsheim E (2015) Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am J Physiol Endocrinol Metab 309:E224-32. Skeletal muscle Human
Tam 2015 Eur J Appl Physiol 2015 Tam E, Bruseghini P, Calabria E, Sacco LD, Doria C, Grassi B, Pietrangelo T, Pogliaghi S, Reggiani C, Salvadego D, Schena F, Toniolo L, Verratti V, Vernillo G, Capelli C (2015) Gokyo Khumbu/Ama Dablam Trek 2012: effects of physical training and high-altitude exposure on oxidative metabolism, muscle composition, and metabolic cost of walking in women. Eur J Appl Physiol 116:129-44. Skeletal muscle Human
Whitfield 2015 J Physiol 2015 Whitfield J, Ludzki A, Heigenhauser GJ, Senden JM, Verdijk LB, van Loon LJ, Spriet LL, Holloway GP (2015) Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle. J Physiol 594:421-35. Skeletal muscle Human
Vincent 2015 Front Physiol 2015 Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51. Skeletal muscle Human
Christiansen 2015 J Vet Med Sci 2015 Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75. Heart
Skeletal muscle
Cat
Grabez 2015 J Anim Sci 2015 Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79. Skeletal muscle Bovines
Herbst 2015 J Physiol 2015 Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801. Nervous system Mouse
Kruse 2015 Aging Cell 2015 Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99. Skeletal muscle Mouse
Lantier 2015 Diabetes 2015 Lantier L, Williams AS, Williams IM, Yang KK, Bracy DP, Goelzer M, James FD, Gius D, Wasserman DH (2015) SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high fat fed mice. Diabetes 64:3081-92. Skeletal muscle Mouse
Garcia 2015 FASEB J 2015 García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75. Heart Mouse
Houben 2015 Mitochondrion 2015 Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104. Skeletal muscle Horse
Boutant 2015 Mol Metab 2015 Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2015) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31. Skeletal muscle
Liver
Fat
Mouse
George 2015 BA Thesis 2015 George M (2015) Assessing mitochondrial lactate oxidation in male rat permeabilized skeletal muscle fibers highlights important experimental considerations. BA Thesis 1-32. Skeletal muscle Rat
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol 2015 Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55. Heart Fishes
Boerma 2015 Radiat Res 2015 Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SP (2015) Effects of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9. Heart Mouse
Hansen 2015 Obesity (Silver Spring) 2015 Hansen M, Lund MT, Gregers E, Kraunsøe R, Van Hall G, Helge JW, Dela F (2015) Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB. Obesity (Silver Spring) 23:2022-9. Fat Human
Bratic 2015 Nat Commun 2015 Bratic A, Kauppila TE, Macao B, Grönke S, Siibak T, Stewart JB, Baggio F, Dols J, Partridge L, Falkenberg M, Wredenberg A, Larsson NG (2015) Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies. Nat Commun 6:8808. Drosophila Hexapods
Coen 2015 Diabetes 2015 Coen PM, Menshikova EV, Distefano G, Zheng D, Tanner CJ, Standley RA, Helbling NL, Dubis GS, Ritov VB, Xie H, Desimone ME, Smith SR, Stefanovic-Racic M, Toledo FG, Houmard JA, Goodpaster BH (2015) Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery. Diabetes 64:3737-50. Skeletal muscle Human
Hanssen 2015 Nat Med 2015 Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P (2015) Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nat Med 21:863-5. Skeletal muscle Human
Ydfors 2015 J Physiol 2015 Ydfors M, Hughes MC, Laham R, Schlattner U, Norrbom J, Perry CG (2015) Modelling in vivo creatine/phosphocreatine in vitro reveal divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic exercise. J Physiol [Epub ahead of print]. Skeletal muscle Human
Nelson 2015 Master Thesis 2015 Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53. Heart Other cell lines Human
Mouse
Saraf 2015 J Burn Care Res 2015 Saraf MK, Herndon DN, Porter C, Toliver-Kinsky T, Radhakrishnan R, Chao T, Chondronikola M, Sidossis LS (2015) Morphological changes in subcutaneous white adipose tissue after severe burn injury. J Burn Care Res 37:e96-e103. Fat Human
Dueregger 2015 PLoS One 2015 Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704. Genital Other cell lines Human
De Andrade 2015 Exp Cell Res 2015 de Andrade DC, de Carvalho SN, Pinheiro D, Thole AA, Moura AS, de Carvalho L, Cortez EA (2015) Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats. Exp Cell Res 336:15-22. Liver Rat
Banerjee 2015 Placenta 2015 Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32. Genital Human
Ludzki 2015 Diabetes 2015 Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79. Skeletal muscle Human
Mouse
Williams 2015 J Biol Chem 2015 Williams AS, Kang L, Zheng J, Grueter CA, Bracy DP, James FD, Pozzi A, Wasserman DH (2015) Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. J Biol Chem 290:6546-57. Liver Other cell lines Mouse
Boushel 2015 Scand J Med Sci Sports 2015 Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43. Skeletal muscle Human
Christiansen 2015 Am J Physiol Heart Circ Physiol 2015 Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47. Heart
Skeletal muscle
Cat
Gnaiger 2015 Scand J Med Sci Sports 2015 Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. Scand J Med Sci Sports 25 (Suppl 4):126–34. Skeletal muscle Human
Duicu 2015 Biomed Res Int 2015 Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437. Heart Human
Wuest 2015 J Physiol 2015 Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40. Heart Rat
Katunga 2015 Mol Metab 2015 Katunga LA, Gudimella P, Efird JT, Abernathy S, Mattox TA, Beatty C, Darden TM, Thayne KA, Alwair H, Kypson AP, Virag JA, Anderson EJ (2015) Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. Mol Metab 4:493-506. Heart Mouse
Herbst 2015 Metabolism 2015 Herbst EA, Roussakis C, Matravadia S, Holloway GP (2015) Chronic treadmill running does not enhance mitochondrial oxidative capacity in the cortex or striatum. Metabolism 64:1419-25. Skeletal muscle
Nervous system
Mouse
Senyilmaz 2015 Nature 2015 Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8. Drosophila
Kilbaugh 2015 Exp Neurol 2015 Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144. Nervous system Pig
Hanssen 2015 Diabetes 2015 Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes [Epub ahead of print]. Skeletal muscle Human
Baris 2015 Am J Physiol Regul Integr Comp Physiol 2015 Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96. Heart Fishes
Paglialunga 2015 Diabetologia 2015 Paglialunga S, Ludzki A, Root-McCaig J, Holloway GP (2015) In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice. Diabetologia 58:1071-80. Fat Mouse
Ping 2015 Oxid Med Cell Longev 2015 Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825. Heart Rat
Schrauwen-Hinderling 2015 Antioxid Redox Signal 2015 Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51. Heart
Skeletal muscle
Human
MiPNet12.23 FibreRespiration 2014-11-07
O2k-Protocols contents
Mitochondrial respiration in permeabilized fibres: Needle biopsies from horse skeletal muscle.
Skeletal muscle Horse
MiPNet12.01 Suppl T-issue 2014-07-20
O2k-Protocols contents
MitoPathways at the Q-junction: mouse skeletal muscle fibres.
Skeletal muscle Mouse
Lou 2014b PLoS One 2014 Lou PH, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling. PLoS One 9:e104971. Heart Rat
Herbst 2014 J Physiol 2014 Herbst EA, Paglialunga S, Gerling C, Whitfield J, Mukai K, Chabowski A, Heigenhauser GJ, Spriet LL, Holloway GP (2014) Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle. J Physiol 592:1341-52. Skeletal muscle Human
Serteyn 2014 Bioenergetics 2014 Serteyn D, de la Rebière de Pouyade G, Sandersen C, Salciccia A, Grulke S, Mouithys-Mickalad A, Franck T, Lejeune JP, Ceusters Justine D (2014) Muscle mitochondrial dysfunction in horses affected by acute laminitis. Bioenergetics 3:1-7. Skeletal muscle Horse
Khan 2014 J Comp Physiol 2014 Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ (2014) Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae). J Comp Physiol 184:991-1001. Skeletal muscle Fishes
Chu 2014 PLoS One 2014 Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR (2014) Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia. PLoS One 9:e100609. Liver Mouse
Larsen 2014 Anal Biochem 2014 Larsen S, Kraunsøe R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8. Skeletal muscle Human
Mouse
Miquel 2014 Free Radic Biol Med 2014 Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P (2014) Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radic Biol Med 70:204-13. Skeletal muscle
Nervous system
Mouse
De Palma 2014 Skelet Muscle 2014 De Palma C, Morisi F, Pambianco S, Assi E, Touvier T, Russo S, Perrotta C, Romanello V, Carnio S, Cappello V, Pellegrino P, Moscheni C, Bassi MT, Sandri M, Cervia D, Clementi E (2014) Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation. Skelet Muscle 4:22. Skeletal muscle Mouse
Sims 2014 FASEB J 2014 Sims C, Patil N, MacMillian-Crow LA, Mayeux P (2014) Mitochondrial superoxide generation in the rat pup kidney during sepsis. FASEB J 28:1063.7. Rat
Ambrosio 2014 Free Radic Biol Med 2014 Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster BH, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A (2014) Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med 74C:64-73. Skeletal muscle Mouse
Cavalcanti-de-Albuquerque 2014 J Appl Physiol 2014 Cavalcanti-de-Albuquerque JP, Salvador IC, Martins EL, Jardim-Messeder D, Werneck-de-Castro JP, Galina A, Carvalho DP (2014) Role of estrogen on skeletal muscle mitochondrial function in ovariectomized rats: a time course study in different fiber types. J Appl Physiol 116:779-89. Skeletal muscle Rat
DeLany 2014 J Clin Endocrinol Metab 2014 DeLany JP, Dube JJ, Standley RA, Distefano G, Goodpaster BH, Stefanovic-Racic M, Coen PM, Toledo FG (2014) Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity. J Clin Endocrinol Metab 99:4307-14. Skeletal muscle Human
Garratt 2014 Proc Natl Acad Sci U S A 2014 Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24. Liver Mouse
Tippets 2014 BMC Cardiovasc Disord 2014 Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT (2014) Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 14:165. Heart Other cell lines Mouse
Rat
Thatcher 2014 Am J Physiol Endocrinol Metab 2014 Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT (2014) Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab 307:E919-27. Skeletal muscle Human
Mouse
Larsen 2014 Biochim Biophys Acta 2014 Larsen S, Díez-Sánchez C, Rabøl R, Royo IA, Dela F, Helge JW (2014) Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H. Biochim Biophys Acta 1837:226-31. Skeletal muscle Human
Shama 2014 Funct Ecol 2014 Shama LNS, Strobel A, Mark FC, Wegner KM (2014) Transgenerational plasticity in marine sticklebacks: maternal effects mediate impacts of a warming ocean. Funct Ecol 28:1482–93. Heart Fishes
Gnaiger 2014 MitoPathways 2014
O2k-Protocols
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. OROBOROS MiPNet Publications, Innsbruck:80 pp.
Heart
Skeletal muscle
Fibroblast Human
Mouse
Iftikar 2014 Thesis University of Auckland 2014 Iftikar FI (2014) Testing the role of heart mitochondrial stability and function in heart failure of ectotherms exposed to heat stress. Thesis University of Auckland:167pp. Heart Fishes
Lou 2014 PLoS One 2014 Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) The mechanism of intralipid®-mediated cardioprotection Complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. PLoS One 9:e87205. Heart Rat
Gouspillou 2014 FASEB J 2014 Gouspillou G, Sgarioto N, Kapchinsky S, Purves-Smith F, Norris B, Pion CH, Barbat-Artigas S, Lemieux F, Taivassalo T, Morais JA, Aubertin-Leheudre M, Hepple RT (2014) Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J 28:1621-33. Skeletal muscle Human
Anmann 2014 Biochim Biophys Acta 2014 Anmann T, Varikmaa M, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Saks V, Kaambre T (2014) Formation of highly organized intracellular structure and energy metabolism in cardiac muscle cells during postnatal development of rat heart. Biochim Biophys Acta 1837:1350-61. Heart Rat
Morand 2014 Eur J Nutr 2014 Morand R, Bouitbir J, Felser A, Hench J, Handschin C, Frank S, Krähenbühl S (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr 53:1313-25. Skeletal muscle Mouse
Baggio 2014 Nucleic Acids Res 2014 Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG5 (2014) Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42:13920-38. Drosophila Hexapods
Soltysinska 2014 PLoS One 2014 Soltysinska E, Bentzen BH, Barthmes M, Hattel H, Thrush AB, Harper ME, Qvortrup K, Larsen FJ, Schiffer TA, Losa-Reyna J, Straubinger J, Kniess A, Thomsen MB, Brüggemann A, Fenske S, Biel M, Ruth P, Wahl-Schott C, Boushel RC, Olesen SP, Lukowski R (2014) KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. PLoS One 9:e103402. Heart
Skeletal muscle
Mouse
Porter 2014 Am J Physiol 2014 Porter C, Herndon DN, Børsheim E, Chao T, Reidy P, Borack M, Rasmussen BB, Chondronikola M, Saraf M, Sidossis LS (2014) Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults. Am J Physiol 307:E462-7. Skeletal muscle Human
Patil 2014 Am J Physiol Renal Physiol 2014 Patil NK, Parajuli N, Macmillan-Crow LA, Mayeux PR (2014) Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria targeted antioxidant mitigates injury. Am J Physiol Renal Physiol 306:F734-43. Kidney Mouse
Dube 2014 Am J Physiol Endocrinol Metab 2014 Dube JJ, Coen PM, DiStefano G, Chacon AC, Helbling NL, Desimone ME, Stafanovic-Racic M, Hames KC, Despines AA, Toledo FG, Goodpaster BH (2014) Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance. Am J Physiol Endocrinol Metab 307:E1117-24. Skeletal muscle Human
Chicco 2014 J Exp Biol 2014 Chicco AJ, Le CH, Schlater AE, Nguyen AD, Kaye SD, Beals JW, Scalzo RL, Bell C, Gnaiger E, Costa DP, Crocker DE, Kanatous SB (2014) High fatty acid oxidation capacity and phosphorylation control despite elevated leak and reduced respiratory capacity in northern elephant seal muscle mitochondria. J Exp Biol 217:2947-55. Skeletal muscle Human
Other mammals
Robach 2014 Med Sci Sports Exerc 2014 Robach P, Bonne T, Flück D, Bürgi S, Toigo M, Jacobs R, Lundby C (2014) Hypoxic training: effect on mitochondrial function and aerobic performance in hypoxia. Med Sci Sports Exerc 46:1936-45. Skeletal muscle Human
Beaudoin 2014 J Physiol 2014 Beaudoin MS, Perry CC, Arkell A, Chabowski A, Simpson JA, Wright DC, Holloway GP (2014) In the ZDF rat, impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede the development of diabetic cardiomyopathy are prevented by resveratrol supplementation. J Physiol 592:2519-33. Heart Rat
Zachariah 2014 Diabetes 2014 Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR (2014) Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes 63:1560-71. Skeletal muscle Mouse
Preau 2014 Thesis University Lille 2014 Preau S (2014) Implication du cytosquelette dans les dysfonctions myocardiques : exemple de la cardiomyopathie septique. Thesis University Lille 155pp. Heart Mouse
Guadalupe-Grau 2014 J Sports Sci 2014 Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2014) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 26:1-9. Skeletal muscle Human
Gram 2014 Exp Gerontol 2014 Gram M, Vigelsoe A, Yokota T, Hansen CN, Helge JW, Hey-Mogensen M, Dela F (2014) Two weeks of one-leg immobilization decreases skeletal muscle 2 respiratory capacity equally in young and elderly men. Exp Gerontol 58C:269-78. Skeletal muscle Human
Ryan 2014 J Physiol 2014 Ryan TE, Brophy P, Lin CT, Hickner RC, Neufer PD (2014) Assessment of in vivo skeletal muscle mitochondrial respiratory capacity in humans by near-infrared spectroscopy: a comparison with in situ measurements. J Physiol 592:3231-41. Skeletal muscle Human
Jelenik 2014 Diabetes 2014 Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67. Skeletal muscle
Liver
Mouse
Larsen 2014 World J Diabetes 2014 Larsen S, Skaaby S, Helge JW, Dela F (2014) Effects of exercise training on mitochondrial function in patients with type 2 diabetes. World J Diabetes 5:482-92. Skeletal muscle Human
Correa 2014 Crit Care Med 2014 Corrêa TD, Jeger V, Pereira AJ, Takala J, Djafarzadeh S, Jakob SM (2014) Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Crit Care Med 42:e550-9. Heart
Liver
Kidney
Pig
Chakraborty 2014 J Cardiovasc Dis 2014 Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459. Heart
Blood cells
Rat
Phielix 2014 Diabetologia 2014 Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81. Skeletal muscle Human
Boushel 2014 Acta Physiol (Oxf) 2014 Boushel RC, Ara I, Gnaiger E, Helge JW, Gonzalez-Alonzo J, Munck-Andersen T, Sondergaard H, Damsgaard R, van Hall G, Saltin B, Calbet JA (2014) Low intensity training increases peak arm VO2 by enhancing both convective and diffusive O2 delivery. Acta Physiol (Oxf) 211:122-34. Skeletal muscle Human
Slinde 2014 freepatentsonline.com 2014 Slinde E, Egelandsdal B (2014) Meat treatment and preservation method. Freepatentsonline.com 14/128207. Skeletal muscle Bovines
Williams 2014 PLoS One 2014 Williams CB, Hughes MC, Edgett BA, Scribbans TD, Simpson CA, Perry CG, Gurd BJ (2014) An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo. PLoS One 9:e102406. Skeletal muscle Human
Montaigne 2014 Circulation 2014 Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B (2014) Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in Type 2 Diabetic but not in obese patients. Circulation 130:554-64. Heart Human
Kaldma 2014 Int J Biochem Cell Biol 2014 Kaldma A, Klepinin A, Chekulayev V, Mado K, Shevchuk I, Timohhina N, Tepp K, Kandashvili M, Varikmaa M, Koit A, Planken M, Heck K, Truu L, Planken A, Valvere V, Rebane E, Kaambre T (2014) An in situ study of bioenergetic properties of human colorectal cancer: The regulation of mitochondrial respiration and distribution of flux control among the components of ATP synthasome. Int J Biochem Cell Biol 55C:171-86. Genital Human
Boushel 2014 Pro Can Soc Exercise Physiol 2014 Boushel RC, Hattel H, Saltin B (2014) Lifelong endurance training keeps mitochondria young. Pro Can Soc Exercise Physiol S6. Skeletal muscle Human
Ost 2014 PLoS One 2014 Ost M, Werner F, Dokas J, Klaus S, Voigt A (2014) Activation of AMPKa2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS One 14:e94689. Skeletal muscle Mouse
Neves 2014 J Nutr Biochem 2014 Neves FA, Cortez E, Bernardoa AF, Mattos ABM, Vieira AK, Malafaia TO, Thole AA, Rodrigues-Cunha ACS, Garcia-Souza EP, Sichieri R, Moura AS (2014) Heart energy metabolism impairment in Western-diet induced obese mice. J Nutr Biochem 25:50-57. Heart Mouse
Ludzki 2014 Thesis 2014 Ludzki AC (2014) Palmitoyl-CoA inhibition of mitochondrial ADP sensitivity is attenuated by exercise training in human skeletal muscle. Master's Thesis 1-86. Skeletal muscle Human
Mouse
Kupsch 2014 J Neural Transm 2014 Kupsch A, Schmidt W, Gizatullina Z, Debska-Vielhaber G, Voges J, Striggow F, Panther P, Schwegler H, Heinze HJ, Vielhaber S, Gellerich FN (2014) 6-Hydroxydopamine impairs mitochondrial function in the rat model of Parkinson's disease: respirometric, histological, and behavioral analyses. J Neural Transm 121:1245-57. Nervous system Rat
Jacobs 2013 Exp Physiol 2013 Jacobs R, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2013) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55. Skeletal muscle Human
Camporez 2013 Endocrinology 2013 Camporez JP, Jornayvaz FR, Petersen M, Pesta D, Guigni BA, Serr J, Zhang D, Kahn M, Samuel VT, Jurczak MJ, Shulman GI (2013) Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice. Endocrinology 154:3099-109. Skeletal muscle
Liver
Fat
Mouse
Salvadego 2013 J Appl Physiol 2013 Salvadego D, Domenis R, Lazzer S, Porcelli S, Rittweger J, Rizzo G, Mavelli I, Simunic B, Pisot R, Grassi B (2013) Skeletal muscle oxidative function in vivo and ex vivo in athletes with marked hypertrophy from resistance training. J Appl Physiol 114:1527-35. Skeletal muscle Human
Yin 2013 Cell Metab 2013 Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel RC, Harper ME, Rudnicki MA (2013) MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab 17:210-24. Skeletal muscle
Fat
Mouse
Hughey 2013 Thesis University of Calgary - Canada 2013 Hughey C (2013) Characterizing the relationship between energy metabolism and mesenchymal stem cell therapy in the infarcted heart. Thesis University of Calgary - Canada -pp. Heart Mouse
Chu 2013 PLoS One 2013 Chu MJ, Phillips AR, Hosking AW, Macdonald JR, Bartlett AS, Hickey AJ (2013) Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One 8:e79097. Liver Human
Rat
Smith 2013 Thesis The University of Guelph - Canada 2013 Smith BK (2013) Investigations into the regulation of skeletal muscle mitochondrial metabolism. Thesis The University of Guelph - Canada 139pp. Skeletal muscle Rat
Segalés 2013 Am J Physiol Endocrinol Metab 2013 Segalés J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A (2013) A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab 305:1208-21. Skeletal muscle
Liver
Other cell lines Mouse
Vielhaber 2013 Acta Neuropathol 2013 Vielhaber S, Debska-Vielhaber G, Peeva V, Schoeler S, Kudin AP, Minin I, Schreiber S, Dengler R, Kollewe K, Zuschratter W, Kornblum C, Zsurka G, Kunz WS (2013) Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion. Acta Neuropathol 125:245-56. Skeletal muscle Human
Duicu 2013 Mol Cell Biochem 2013 Duicu O, Juşcă C, Falniţă L, Mirică S, Maximov D, Firă-Mladinescu O, Muntean D (2013) Substrate-specific impairment of mitochondrial respiration in permeabilized fibers from patients with coronary heart disease versus valvular disease. Mol Cell Biochem 379:229-34. Heart Human
Crane 2013 PLoS One 2013 Crane JD, Abadi A, Hettinga BP, Ogborn DI, Macneil LG, Steinberg GR, Tarnopolsky MA (2013) Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. PLoS One 8:e81879. Skeletal muscle Mouse
Vijgen 2013 Surg Obes Relat Dis 2013 Vijgen GH, Bouvy ND, Hoeks J, Wijers S, Schrauwen P, van Marken Lichtenbelt WD (2013) Impaired skeletal muscle mitochondrial function in morbidly obese patients is normalized one year after bariatric surgery. Surg Obes Relat Dis 9:936-41. Skeletal muscle Human
Wiedemann 2013 Int J Mol Sci 2013 Wiedemann D, Schachner T, Bonaros N, Dorn M, Andreas M, Kocher A, Kuznetsov AV (2013) Impact of cold ischemia on mitochondrial function in porcine hearts and blood vessels. Int J Mol Sci 14:22042-51. Heart
Endothelial;epithelial;mesothelial cell
Pig
Varikmaa 2013 Thesis Tallinn University of Technology 2013 Varikmaa M (2013) Structural and Functional Studies of Mitochondrial Respiration Regulation in Muscle Cells. Thesis Tallinn University of Technology - Tallinn pp147. Skeletal muscle Rat
Pichaud 2013 J Exp Biol 2013 Pichaud N, Garratt M, Ballard JWO, Brooks RC (2013) Physiological adaptations to reproduction II. Mitochondrial adjustments in livers of lactating mice. J Exp Biol 216:2889-95. Liver Mouse
Costa 2013 Cell Death Dis 2013 Costa AC, Loh SH, Martins LM (2013) Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467. Drosophila
Rojahn 2013 Thesis Norwegian University of Life Sciences - Ås 2013 Rojahn L (2013) Effects of micronutrients on survival and mitochondrial viability in honey bees (Apis mellifera). Thesis Norwegian University of Life Sciences - Ås: 41 pp. Skeletal muscle Hexapods
Holmstroem 2013 Metabolism 2013 Holmström MH, Tom RZ, Björnholm M, Garcia-Roves PM, Zierath JR (2013) Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice. Metabolism 62:1258-67. Skeletal muscle
Liver
Mouse
Hughey 2013 Cardiovasc Diabetol 2013 Hughey CC, Ma L, James FD, Bracy DP, Wang Z, Wasserman DH, Rottman JN, Hittel DS, Shearer J (2013) Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart. Cardiovasc Diabetol 12:128. Heart Mouse
Perry 2013 Diabetes 2013 Perry CG, Kane DA, Lanza IR, Neufer PD (2013) Methods for assessing mitochondrial function in diabetes. Diabetes 62:1041-53. Skeletal muscle Human
Wohlwend 2013 Thesis Norwegian University of Science and Technology - Trondheim 2013 Wohlwend M (2013) Mitochondrial function in health and disease - high-resolution respirometry in rats inbred for high vs. low running capacity. Thesis Norwegian University of Science and Technology - Trondheim: 44pp. Heart
Skeletal muscle
Rat
Jacobs 2013 J Appl Physiol 2013 Jacobs R, Flück D, Bonne TC, Bürgi S, Christensen PM, Toigo M, Lundby C (2013) Improvements in exercise performance 1 with high-intensity interval training 2 coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol 115:785-93. Skeletal muscle Human
Reilly 2013 J Exp Biol 2013 Reilly BD, Hickey AJ, Cramp RL, Franklin CE (2013) Decreased hydrogen peroxide production and mitochondrial respiration in skeletal muscle but not cardiac muscle of the green-striped burrowing frog, a natural model of muscle disuse. J Exp Biol 217:1087-93. Heart
Skeletal muscle
Amphibians
Murray 2013 Exp Physiol 2013 Murray AJ (2013) Of mice and men (and muscle mitochondria). Exp Physiol 98:879-80. Skeletal muscle Human
Mouse
Lally 2013 PLoS One 2013 Lally JS, Herbst EA, Matravadia S, Maher AC, Perry CG, Ventura-Clapier R, Holloway GP (2013) Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics. PLoS One 8:e55660. Skeletal muscle Rat
Galli 2013 J Exp Biol 2013 Galli GL, Lau GY, Richards JG (2013) Beating oxygen: chronic anoxia exposure reduces mitochondrial F1FO-ATPase activity in turtle (Trachemys scripta) heart. J Exp Biol 216:3283-93. Heart Reptiles
Ye 2013 Aging 2013 Ye L, Widlund AL, Sims CA, Lamming DW, Guan Y, Davis JG, Sabatini DM, Harrison DE, Vang O, Baur JA (2013) Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance. Aging (Albany NY) 5:539-50. Other cell lines Mouse
Smith 2013 J Physiol 2013 Smith BK, Perry CG, Herbst EA, Ritchie IR, Beaudoin MS, Smith JC, Neufer PD, Wright DC, Holloway GP (2013) Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol. J Physiol 591:6089-101. Skeletal muscle Rat
Coen 2013 J Gerontol A Biol Sci Med Sci 2013 Coen PM, Jubrias SA, Distefano G, Amati F, Mackey DC, Glynn NW, Manini TM, Wohlgemuth SE, Leeuwenburgh C, Cummings SR, Newman AB, Ferrucci L, Toledo FG, Shankland E, Conley KE, Goodpaster BH (2013) Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults. J Gerontol A Biol Sci Med Sci 68:447-55. Skeletal muscle Human
Iftikar 2013 PLoS One 2013 Iftikar FI, Hickey AJ (2013) Do mitochondria limit hot fish hearts? Understanding the role of mitochondrial function with heat stress in Notolabrus celidotus. PLoS One 8:e64120. Heart Fishes
Smith 2013 Biochem J 2013 Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2013) Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456:427-39. Skeletal muscle Other cell lines Mouse
Kristensen 2013 PLoS One 2013 Kristensen JM, Larsen S, Helge JW, Dela F, Wojtaszewski JFP (2013) Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS One 8:e53533. Skeletal muscle Mouse
Correa 2013 Crit Care 2013 Corrêa TD, Vuda M, Takala J, Djafarzadeh S, Silva E, Jakob SM (2013) Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Crit Care 17:R21. Skeletal muscle
Liver
Pig
Pichaud 2013 J Bioenerg Biomembr 2013 Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2013) Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration. J Bioenerg Biomembr 45:25-35. Skeletal muscle Hexapods
Montaigne 2013 J Am Coll Cardiol 2013 Montaigne D, Marechal X, Lefebvre P, Modine T, Fayad G, Dehondt H, Hurt C, Coisne A, Koussa M, Remy-Jouet I, Zerimech F, Boulanger E, Lacroix D, Staels B, Neviere R (2013) Mitochondrial dysfunction as an arrhythmogenic substrate. J Am Coll Cardiol 62:1466-73. Heart Human
Jacobs 2013 J Gerontol A Biol Sci Med Sci 2013 Jacobs R, Diaz V, Soldini L, Haider T, Thomassen M, Nordsborg NB, Gassmann M, Lundby C (2013) Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. J Gerontol A Biol Sci Med Sci 68:1010-22. Skeletal muscle Mouse
Van der Laans 2013 J Clin Invest 2013 van der Lans AA, Hoeks J, Brans B, Vijgen GH, Visser MG, Vosselman MJ, Hansen J, Jörgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2013) Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest 123:3395-403. Skeletal muscle Human
Jacobs 2013 Am J Physiol Endocrinol Metab 2013 Jacobs R, Meinild AK, Nordsborg NB, Lundby C (2013) Lactate oxidation in human skeletal muscle mitochondria. Am J Physiol Endocrinol Metab 304:686-94. Skeletal muscle Human
La Guardia 2013 Front Physiol 2013 La Guardia PG, Alberici LC, Ravagnani FG, Catharino RR, Vercesi AE (2013) Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation. Front Physiol 4:103. Skeletal muscle Rat
Martin 2013 Crit Care Med 2013 Martin AD, Joseph AM, Beaver TM, Smith BK, Martin TD, Berg K, Hess PJ, Deoghare HV, Leeuwenburgh C (2013) Effect of intermittent phrenic nerve stimulation during cardiothoracic surgery on mitochondrial respiration in the human diaphragm. Crit Care Med 42:e152-6. Skeletal muscle Human
Yuzefovych 2013 Endocrinology 2013 Yuzefovych LV, Schuler AM, Chen J, Alvarez DF, Eide L, Ledoux SP, Wilson GL, Rachek LI (2013) Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of OGG1. Endocrinology 154:2640-9. Skeletal muscle Mouse
Dos Santos 2013 Bio Open 2013 Dos Santos RS, Galina A, Da-Silva WS (2013) Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle. Bio Open 2:82-7. Skeletal muscle Fishes
Vijgen 2013 J Clin Endocrinol Metab 2013 Vijgen GH, Sparks LM, Bouvy ND, Schaart G, Hoeks J, van Marken Lichtenbelt WD, Schrauwen P (2013) Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. J Clin Endocrinol Metab 98:E1230-4. Fat Human
Kaambre 2013 Front Physiol 2013 Kaambre T, Chekulayev V, Shevchuk I, Tepp K, Timohhina N, Varikmaa M, Bagur R, Klepinin A, Anmann T, Koit A, Kaldma A, Guzun R, Valvere V, Saks V (2013) Metabolic control analysis of respiration in human cancer tissue. Front Physiol 4:151. Endothelial;epithelial;mesothelial cell Human
Varikmaa 2013 J Bioenerg Biomembr 2013 Varikmaa M, Guzun R, Grichine A, Gonzalez-Granillo M, Usson Y, Boucher F, Kaambre T, Saks V (2013) Matters of the heart in bioenergetics: mitochondrial fusion into continuous reticulum is not needed for maximal respiratory activity. J Bioenerg Biomembr 45:319-31. Heart Other cell lines Mouse
Stephenson 2013 Thesis Royal Melbourne Institute of Technology - Melbourne 2013 Stephenson EJ (2013) Mitochondrial function in metabolic health. Thesis Royal Melbourne Institute of Technology - Melbourne: 106pp. Skeletal muscle Rat
Larsen 2013 J Am Coll Cardiol 2013 Larsen S, Stride N, Hey-Mogensen M, Hansen CN, Bang LE, Bundgaard H, Nielsen LB, Helge JW, Dela F (2013) Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance. J Am Coll Cardiol 61:44-53. Skeletal muscle Human
Gilliam 2013 Free Radic Biol Med 2013 Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD (2013) The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radic Biol Med 65:988-96. Skeletal muscle Rat
Lou 2013 Cardiovasc Res 2013 Lou PH, Zhang L, Lucchinetti E, Heck M, Affolter A, Gandhi M, Kienesberger PC, Hersberger M, Clanachan AS, Zaugg M (2013) Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury. Cardiovasc Res 97:251-61. Heart Rat
Stride 2013 Eur J Heart Fail 2013 Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F (2013) Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 15:150-7. Heart Human
Cook 2013 J Exp Biol 2013 Cook DG, Iftikar FI, Baker DW, Hickey AJ, Herbert NA (2013) Low-O2 acclimation shifts the hypoxia avoidance behaviour of snapper (Pagrus auratus) with only subtle changes in aerobic and anaerobic function. J Exp Biol 216:369-78. Heart
Skeletal muscle
Fishes
Lopez-Erauskin 2013 Hum Mol Genet 2013 López-Erauskin J, Galino J, Ruiz M, Cuezva JM, Fabregat I, Cacabelos D, Boada J, Martínez J, Ferrer I, Pamplona R, Villarroya F, Portero-Otín M, Fourcade S, Pujol A (2013) Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy. Hum Mol Genet 22:3296-305. Nervous system Mouse
Joseph 2012 Aging Cell 2012 Joseph AM, Adhihetty PJ, Buford TW, Wohlgemuth SE, Lees HA, Nguyen LM, Aranda JM, Sandesara BD, Pahor M, Manini TM, Marzetti E, Leeuwenburgh C (2012) The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals. Aging Cell 11:801-9. Skeletal muscle Human
Kuznetsov 2012 Biochem J 2012 Kuznetsov AV, Guzun R, Boucher F, Bagur R, Kaambre T, Saks V (2012) Mysterious Ca2+-independent muscular contraction: déjà vu. Biochem J 445:333-6. Heart
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Wuest 2012 Am J Physiol Heart Circ Physiol 2012 Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411. Skeletal muscle Rat
Lin 2012 FASEB J 2012 Lin CT, Kelsey H, Fisher-Wellman KH, Perry CG, Kozy R, Lark DS, Gilliam LA, Smith CD, Neufer PD (2012) Low Intensity Exercise Attenuates Acute Lipid Loading-Induced Alterations in Mitochondrial Function in Rat Skeletal Muscle . FASEB J 1144.11. Skeletal muscle Rat
Stride 2012 Front Physiol 2012 Stride N, Larsen S, Treebak JT, Hansen CN, Hey-Mogensen M, Speerschneider T, Jensen TE, Jeppesen J, Wojtaszewski JF, Richter EA, Køber L, Dela F (2012) 5'-AMP activated protein kinase is involved in the regulation of myocardial β-oxidative capacity in mice. Front Physiol 3:33. Heart Mouse
McFarlan 2012 J Biol Chem 2012 McFarlan JT, Yoshida Y, Jain SS, Han XX, Snook LA, Lally J, Smith BK, Glatz JF, Luiken JJ, Sayer RA, Tupling AR, Chabowski A, Holloway GP, Bonen A (2012) In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance and training-induced adaptation of fatty acid oxidation. J Biol Chem 287:23502-16. Skeletal muscle Mouse
Jacobs 2012 J Appl Physiol 2012 Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol 114:344-50. Skeletal muscle Human
Hughey 2012 Am J Physiol Endocrinol Metab 2012 Hughey CC, Johnsen VL, Ma L, James FD, Young PP, Wasserman DH, Rottman JN, Hittel DS, Shearer J (2012) Mesenchymal stem cell transplantation for the infarcted heart: a role in minimizing abnormalities in cardiac-specific energy metabolism. Am J Physiol Endocrinol Metab 302:E163-72. Heart Mouse
Phielix 2012 Diabetes 2012 Phielix E, Meex R, Ouwens DM, Sparks LM, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance. Diabetes 61:2472-8. Skeletal muscle Human
Oellermann 2012 J Exp Biol 2012 Oellermann M, Poertner HO, Mark FC (2012) Mitochondrial dynamics underlying thermal plasticity of cuttlefish (Sepia officinalis) hearts. J Exp Biol 215:2992-3000. Heart Molluscs
Picard 2012 PLoS One 2012 Picard M, Wright KJ, Ritchie D, Thomas MM, Hepple RT (2012) Mitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium. PLoS One 7:e43003. Heart Rat
Lanza 2012 Cell Metab 2012 Lanza IR, Zabielski P, Klaus KA, Morse DM, Heppelmann CJ, Bergen HR 3rd, Dasari S, Walrand S, Short KR, Johnson ML, Robinson MM, Schimke JM, Jakaitis DR, Asmann YW, Sun Z, Nair KS (2012) Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis. Cell Metab 16:777-88. Skeletal muscle Mouse
Jacobs RA 2012 Exp Physiol 2012 Jacobs R, Díaz V, Meinild AK, Gassmann M, Lundby C (2012) The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Exp Physiol 98:908-21. Skeletal muscle Human
Mouse
Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol 2012 Pichaud N, Rioux P, Blier PU (2012) In situ quantification of mitochondrial respiration in permeabilized fibers of a marine invertebrate with low aerobic capacity. Comp Biochem Physiol A Mol Integr Physiol 161:429-35. Annelids
Lancel 2012 PLoS One 2012 Lancel S, Montaigne D, Marechal X, Marciniak C, Hassoun SM, Decoster B, Ballot C, Blazejewski C, Corseaux D, Lescure B, Motterlini R, Neviere R (2012) Carbon monoxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome. PLoS One 7:e41836. Heart Mouse
Hempenstall 2012 Mech Ageing Dev 2012 Hempenstall S, Page MM, Wallen KR, Selman C (2012) Dietary restriction increases skeletal muscle mitochondrial respiration but not mitochondrial content in C57BL/6 mice. Mech Ageing Dev 133:37-45. Skeletal muscle Mouse
Lemieux 2012 J Bioenerg Biomembr 2012 Lemieux H, Warren BE (2012) An animal model to study human muscular diseases involving mitochondrial oxidative phosphorylation. J Bioenerg Biomembr 44:503-12. Other invertebrates
Plenge 2012 Endocrine Abstracts 2012 Plenge U, Guadeloupe-Grau A, Andersen P, Carsten L, Dela F, Pott F, Jørn H, Belhage B, Boushel RC (2012) Recombinant erythropoietin treatment enhances mitochondrial function in human skeletal muscle. Endocrine Abstracts 29 P302 . Skeletal muscle Human
Pichaud 2012 Evolution 2012 Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2012) Naturally occurring mitochondrial DNA haplotypes exhibit metabolic differences: Insight into functional properties of mitochondria. Evolution 66:3189–97. Skeletal muscle Drosophila Hexapods
Kaambre 2012 J Bioenerg Biomembr 2012 Kaambre T, Chekulayev V, Shevchuk I, Karu-Varikmaa M, Timohhina N, Tepp K, Bogovskaja J, Kütner R, Valvere V, Saks V (2012) Metabolic control analysis of cellular respiration in situ in intraoperational samples of human breast cancer. J Bioenerg Biomembr 44:539-58. Heart
Endothelial;epithelial;mesothelial cell
Human
Rat
Correa 2012 Crit Care Med 2012 Corrêa TD, Vuda M, Blaser AR, Takala J, Djafarzadeh S, Dünser MW, Silva E, Lensch M, Wilkens L, Jakob SM (2012) Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Crit Care Med 40:2841-9. Heart
Skeletal muscle
Nervous system
Liver
Pig
Duicu 2012 Rev Med Chir Soc Med Nat Iasi 2012 Duicu O, Gheorgheosu D, Mirica N, Trancota S, Cristina D, Fira-Mladinescu O, Muntean D (2012) High-resolution respirometry with multiple substrates titration in permeabilized myocardial fibers. Rev Med Chir Soc Med Nat Iasi 116:207-13. Heart Rat
Robach 2012 Br J Sports Med 2012 Robach P, Siebenmann C, Jacobs R, Rasmussen P, Nordsborg N, Pesta D, Gnaiger E, Diaz V, Christ A, Fiedler J, Crivelli N, Secher NH, Pichon A, Maggiorini M, Lundby C (2012) The role of haemoglobin mass on VO2max following normobaric live high-train low in endurance-trained athletes. Br J Sports Med Jul 12. 46:822-7. Skeletal muscle Human
Pesta 2012 Methods Mol Biol 2012
O2k-Protocols
Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibres from small biopsies of human muscle. Methods Mol Biol 810:25-58.
Skeletal muscle HEK
Fibroblast
HUVEC
Other cell lines
Human
Jacobs 2012 FASEB J 2012 Jacobs R, Siebenmann C, Hug M, Toigo M, Meinild AK, Lundby C (2012) Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria. FASEB J 90:1145-60. Skeletal muscle Human
Smith 2012 Biochem J 2012 Smith BK, Perry CG, Koves TR, Wright DC, Smith JC, Neufer PD, Muoio DM, Holloway GP (2012) Identification of a novel malonyl-CoA IC50 for CPT-I: implications for predicting in vivo fatty acid oxidation rates. Biochem J 448:13-20. Skeletal muscle Rat
Boushel 2012 Am J Physiol Regul Integr Comp Physiol 2012 Boushel RC, Fuentes T, Hellsten Y, Saltin B (2012) Opposing effects of nitric oxide and prostaglandin inhibition on muscle mitochondrial VO2 during exercise . Am J Physiol Regul Integr Comp Physiol 303:94-100. Skeletal muscle Human
Correa 2012 Mitochondrion 2012 Correa CC, Aw WC, Melvin RG, Pichaud N, Ballard JWO (2012) Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster. Mitochondrion 12:459-64. Skeletal muscle Drosophila Hexapods
Larsen 2012 J Physiol 2012 Larsen S, Nielsen J, Neigaard Nielsen C, Nielsen LB, Wibrand F, Stride N, Schroder HD, Boushel RC, Helge JW, Dela F, Hey-Mogensen M (2012) Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects. J Physiol 590:3349-60. Skeletal muscle Human
Lou 2012 Cardiovasc Res 2012 Lou PH, Zhang L, Lucchinetti E, Heck M, Affolter A, Gandhi M, Kienesberger PC, Hersberger M, Clanachan AS, Zaugg M (2012) Infarct-remodeled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischemia/reperfusion injury. Cardiovasc Res 97:251-61. Heart Rat
Hickey 2012 J Comp Physiol B 2012 Hickey AJ, Renshaw GM, Speers-Roesch B, Richards JG, Wang Y, Farrell AP, Brauner CJ (2012) A radical approach to beating hypoxia: depressed free radical release from heart fibres of the hypoxia-tolerant epaulette shark (Hemiscyllum ocellatum). J Comp Physiol B 182:91-100. Heart Fishes
Stephenson 2012 J Appl Physiol (1985) 2012 Stephenson EJ, Stepto NK, Koch LG, Britton SL, Hawley JA (2012) Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1? J Appl Physiol (1985) 113:1403-12. Skeletal muscle Rat
Plenge 2012 Front Physiol 2012 Plenge U, Belhage B, Guadalupe-Grau A, Andersen PR, Lundby C, Dela F, Stride N, Pott FC, Helge JW, Boushel RC (2012) Erythropoietin treatment enhances muscle mitochondrial capacity in humans. Front Physiol 3:50. Skeletal muscle Human
Larsen 2012 CryoLetters 2012 Larsen S, Wright-Paradis C, Gnaiger E, Helge JW, Boushel RC (2012) Cryopreservation of human skeletal muscle impairs mitochondrial function. Cryo Letters 33:170-6. Skeletal muscle Human
Ziegler 2012 Mitochondrion 2012 Ziegler CG, Peng M, Falk MJ, Polyak E, Tsika E, Ischiropoulos H, Bakalar D, Blendy JA, Gasser DL (2012) Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice. Mitochondrion 12:248-57. Nervous system Mouse
Perry 2012 J Physiol 2012 Perry CG, Kane DA, Herbst EA, Mukai K, Lark DS, Wright DC, Heigenhauser GJ, Neufer PD, Spriet LL, Holloway GP (2012) Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. J Physiol 590: 5475-5486. Skeletal muscle Human
Parajuli 2012 PLoS One 2012 Parajuli N, Campbell LH, Marine A, Brockbank KG, Macmillan-Crow LA (2012) MitoQ blunts mitochondrial and renal damage during cold preservation of porcine kidneys. PLoS One 7:e48590. Kidney Pig
Galli 2012 J Ther Bio 2012 Galli GL, Richards JG (2012) The effect of temperature on mitochondrial respiration in permeabilized cardiac fibres from the freshwater turtle, Trachemys scripta. J Ther Bio 37:195–200. Heart Reptiles
Votion 2012 PLoS One 2012 Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One 7:e34890. Skeletal muscle Horse
Falk 2012 EMBO Mol Med 2012 Falk MJ, Polyak E, Zhang Z, Peng M, King R, Maltzman JS, Okwuego E, Horyn O, Nakamaru-Ogiso E, Ostrovsky J, Xie LX, Chen JY, Marbois B, Nissim I, Clarke CF, Gasser DL (2012) Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. EMBO Mol Med 3:410-27. Skeletal muscle
Kidney
Mouse
Perry 2011 Biochem J 2011 Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22. Skeletal muscle Human
Rat
Gam 2011 Clin Physiol Funct Imaging 2011 Gam CM, Nielsen HB, Secher NH, Larsen FS, Ott P, Quistorff B (2011) In cirrhotic patients reduced muscle strength is unrelated to muscle capacity for ATP turnover suggesting a central limitation. Clin Physiol Funct Imaging 31: 169-174. Skeletal muscle Human
Rosca 2011 Biochim Biophys Acta 2011 Rosca M, Minkler P, Hoppel CL (2011) Cardiac mitochondria in heart failure: Normal cardiolipin profile and increased threonine phosphorylation of Complex IV. Biochim Biophys Acta 1807:1373-82. Heart Rat
Dog
Pesta 2011 Am J Physiol Regul Integr Comp Physiol 2011 Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87. Skeletal muscle Human
Lemieux 2011 Int J Biochem Cell Biol 2011 Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. Heart Human
Dai 2011 Circ Res 2011 Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW 2nd, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS (2011) Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res 108:837-46. Heart Mouse
Kane 2011 Am J Physiol Endocrinol Metab 2011 Kane DA, Lin CT, Anderson EJ, Kwak HB, Cox JH, Brophy PM, Hickner RC, Neufer PD, Cortright RN (2011) Progesterone increases skeletal muscle mitochondrial H2O2 emission in non-menopausal women. Am J Physiol Endocrinol Metab 300:E528-35. Skeletal muscle Human
Rabol 2011 Eur J Endocrinol 2011 Rabol R, Svendsen PF, Skovbro M, Boushel RC, Schjerling P, Nilas L, Madsbad S, Dela F (2011) Skeletal muscle mitochondrial function in polycystic ovarian syndrome. Eur J Endocrinol 165:631-7. Skeletal muscle Human
Hughey 2011 J Vis Exp 2011 Hughey CC, Hittel DS, Johnsen VL, Shearer J (2011) Respirometric oxidative phosphorylation assessment in saponin-permeabilized cardiac fibers. J Vis Exp 48: e2431. Heart Mouse
Skovbro 2011 J Appl Physiol 2011 Skovbro M, Boushel RC, Hansen CN, Helge JW, Dela F (2011) High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle. J Appl Physiol 110:1607-14. Skeletal muscle Human
Naimi 2011 Clin Physiol Funct Imaging 2011 Naimi AI, Bourbeau J, Perrault H, Baril J, Wright-Paradis C, Rossi A, Taivassalo T, Sheel AW, Rabøl R, Dela F, Boushel RC (2011) Altered mitochondrial regulation in quadriceps muscles of patients with COPD. Clin Physiol Funct Imaging 31:124-31. Skeletal muscle Human
MacDonald 2011 Am J Physiol Cell Physiol 2011 MacDonald JR, Oellermann M, Rynbeck S, Chang G, Ruggiero K, Cooper GJ, Hickey AJ (2011) Transmural differences in respiratory capacity across the rat left ventricle in health, aging, and streptozotocin-induced diabetes mellitus: evidence that mitochondrial dysfunction begins in the subepicardium. Am J Physiol Cell Physiol 300:C246-55. Heart Rat
Marechal 2011 Clin Sci (Lond) 2011 Marechal X, Montaigne D, Marciniak C, Marchetti P, Hassoun SM, Beauvillain JC, Lancel S, Neviere R (2011) Doxorubicin-induced cardiac dysfunction is attenuated by ciclosporin treatment in mice through improvements in mitochondrial bioenergetics. Clin Sci (Lond) 121:405-13. Heart Mouse
Boushel 2011 Mitochondrion 2011 Boushel RC, Gnaiger E, Calbet JA, Gonzalez-Alonso J, Wright-Paradis C, Sondergaard H, Ara I, Helge JW, Saltin B (2011) Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion 11:303-7. Skeletal muscle Human
Wijers 2011 J Clin Endocrinol Metab 2011 Wijers SL, Schrauwen P, van Baak MA, Saris WH, van Marken Lichtenbelt WD (2011) Beta-adrenergic receptor blockade does not inhibit cold-induced thermogenesis in humans: possible involvement of brown adipose tissue. J Clin Endocrinol Metab 96: E598–605. Skeletal muscle
Fat
Human
Tepp 2011 Biochim Biophys Acta 2011 Tepp K, Shevchuk I, Chekulayev V, Timohhina N, Kuznetsov AV, Guzun R, Saks V, Kaambre T (2011) High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units. Biochim Biophys Acta 1807: 1549-1561. Heart
Picard 2011 PLoS One 2011 Picard M, Taivassalo T, Ritchie D, Wright KJ, Thomas MM, Romestaing C, Hepple RT (2011) Mitochondrial structure and function are disrupted by standard isolation methods. PLoS One 6:e18317. Skeletal muscle Rat
Larsen 2011 Acta Physiol (Oxf) 2011 Larsen S, Kristensen JM, Stride N, Wojtaszewski JF, Helge JW, Dela F (2011) Skeletal muscle mitochondrial respiration in AMPKα2 kinase-dead mice. Acta Physiol (Oxf) 205: 314-320. Skeletal muscle Mouse
Larsen 2011 Diabetologia 2011 Larsen S, Stride N, Hey-Mogensen M, Hansen CN, Andersen JL, Madsbad S, Worm D, Helge JW, Dela F (2011) Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. Diabetologia 54: 1427-1436. Skeletal muscle Human
Jacobs 2011 J Appl Physiol 2011 Jacobs R, Rasmussen P, Siebenmann C, Díaz V, Pesta D, Gnaiger E, Nordsborg NB, Robach P, Lundby C (2011) Determinants of time trial performance and maximal incremental exercise in highly trained endurance athletes. J Appl Physiol 111:1422–30. Skeletal muscle Human
Khalid 2011 Am J Physiol Heart Circ Physiol 2011 Khalid AM, Hafstad AD, Larsen TS, Severson DL, Boardman N, Hagve M, Berge RK, Aasum E (2011) Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice. Am J Physiol Heart Circ Physiol 300:H2116-22. Heart Mouse
Ara 2011 Int J Obes 2011 Ara I, Larsen S, Stallknecht B, Guerra B, Morales-Alamo D, Andersen JL, Ponce-González JG, Guadalupe-Grau A, Galbo H, Calbet JA, Helge JW (2011) Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans. Int J Obes 35: 99-108. Skeletal muscle Human
Anderson 2011 Am J Physiol Heart Circ Physiol 2011 Anderson EJ, Rodriguez E, Anderson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol 300:H118-24. Heart Human
Pasdois 2011 Biochem J 2011 Pasdois P, Parker JE, Griffiths EJ, Halestrap AP (2011) The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia. Biochem J 436:493-505. Heart Rat
Picard 2011 Aging Cell 2011 Picard M, Ritchie D, Wright KJ, Romestaing C, Thomas MM, Rowan SL, Taivassalo T, Hepple RT (2011) Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers. Aging Cell 9:1032–46. Skeletal muscle Rat
Brands 2011 Metabolism 2011 Brands M, Hoeks J, Sauerwein HP, Ackermans MT, Ouwens M, Lammers NM, van der Plas MN, Schrauwen P, Groen AK, Serlie MJ (2011) Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men. Metabolism 60:1398-405. Skeletal muscle Human
Niehusmann 2011 Epilepsy Behav 2011 Niehusmann P, Surges R, von Wrede RD, Elger CE, Wellmer J, Reimann J, Urbach H, Vielhaber S, Bien CG, Kunz WS (2011) Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery. Epilepsy Behav 20:38-43. Skeletal muscle
Nervous system
Human
Smith 2011 Biochem J 2011 Smith BK, Jain SS, Rimbaud S, Dam A, Quadrilatero J, Ventura-Clapier R, Bonen A, Holloway GP (2011) FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation. Biochem J 437:125-34. Skeletal muscle Mouse
Pichaud 2011 Am J Physiol Regul Integr Comp Physiol 2011 Pichaud N, Ballard JW, Tanguay RM, Blier PU (2011) Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes. Am J Physiol Regul Integr Comp Physiol 301:R48-59. Skeletal muscle Drosophila
Timmers 2011 Cell Metab 2011 Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22. Skeletal muscle Human
Votion 2010 Equine Vet J 2010 Votion DM, Fraipont A, Goachet AG, Robert C, van Erck E, Amory H, Ceusters Justine D, de la Rebière de Pouyade G, Franck T, Mouithys-Mickalad A, Niesten A, Serteyn D (2010) Alterations in mitochondrial respiratory function in response to endurance training and endurance racing. Equine Vet J 42 Suppl 38:268-74. Skeletal muscle Horse
Jiang 2010 Am J Physiol Endocrinol Metab 2010 Jiang LQ, Garcia-Roves PM, de Castro Barbosa T, Zierath JR (2010) Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity. Am J Physiol Endocrinol Metab 298:E8-16. Skeletal muscle Mouse
Hoeks 2010 Diabetes 2010 Hoeks J, van Herpen NA, Mensink M, Moonen-Kornips E, van Beurden D, Hesselink MK, Schrauwen P (2010) Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 59:2117-25. Skeletal muscle Human
Iftikar 2010 JEMBE 2010 Iftikar F, MacDonald JR, Hickey AJ (2010) Thermal limits of portunid crab heart mitochondria: Could more thermo-stable mitochondria advantage invasive species? JEMBE 395:232-9. Heart Crustaceans
Lanza 2010 Curr Opin Clin Nutr Metab Care 2010 Lanza IR, Nair KS (2010) Mitochondrial metabolic function assessed in vivo and in vitro. Curr Opin Clin Nutr Metab Care 13:511-7. Skeletal muscle Human
Sepp 2010 Biophys J 2010 Sepp M, Vendelin M, Vija H, Birkedal R (2010) ADP compartmentation analysis reveals coupling between pyruvate kinase and ATPases in heart muscle. Biophys J 98:2785-93. Heart Rat
Lemieux 2010 J Gerontol A Biol Sci Med Sci 2010 Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL (2010) Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J Gerontol A Biol Sci Med Sci 65:1157-64. Heart Rat
Arruda 2010 Endocrinology 2010 Arruda AP, Milanski M, Romanatto T, Solon C, Coope A, Alberici LC, Festuccia WT, Hirabara SM, Ropelle E, Curi R, Carvalheira JB, Vercesi AE, Velloso LA (2010) Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia. Endocrinology 151:683-94. Nervous system Rat
Kadaja 2010 Exp Clin Cardiol 2010 Kadaja L, Eimre M, Paju K, Roosimaa M, Podramaegi T, Kaasik P, Pehme A, Orlova E, Mudist M, Peet N, Piirsoo A, Seene T, Gellerich FN, Seppet EK (2010) Impaired oxidative phosphorylation in overtrained rat myocardium. Exp Clin Cardiol 15:116-27. Heart Rat
Rabol 2010 Diabetes Obes Metab 2010 Rabol R, Boushel RC, Almdal T, Hansen CN, Ploug T, Haugaard SB, Prats C, Madsbad S, Dela F (2010) Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes. Diabetes Obes Metab 12:806-14. Skeletal muscle Human
Kraunsoee 2010 J Physiol 2010 Kraunsøe R, Boushel RC, Hansen CN, Schjerling P, Qvortrup K, Støckel M, Mikines KJ, Dela F (2010) Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity. J Physiol 588:2023-32. Fat Human
Phielix 2010 Diabetologia 2010 Phielix E, Meex R, Moonen-Kornips E, Hesselink MK, Schrauwen P (2010) Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals. Diabetologia 53:1714-21. Skeletal muscle Human
Rabol 2010 J Clin Endocrinol Metab 2010 Rabol R, Larsen S, Hojberg PM, Almdal T, Boushel RC, Haugaard SB, Andersen JL, Madsbad S, Dela F (2010) Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity. J Clin Endocrinol Metab 95:857-63. Skeletal muscle Human
Montaigne 2010 Toxicol Appl Pharmacol 2010 Montaigne D, Marechal X, Baccouch R, Modine T, Preau S, Zannis K, Marchetti P, Lancel S, Neviere R (2010) Stabilization of mitochondrial membrane potential prevents doxorubicin-induced cardiotoxicity in isolated rat heart. Toxicol Appl Pharmacol 244:300-7. Heart Rat
Hilton 2010 J Comp Physiol B 2010 Hilton Z, Clements KD, Hickey AJ (2010) Temperature sensitivity of cardiac mitochondria in intertidal and subtidal triplefin fishes. J Comp Physiol B 180:979-90. Heart Fishes
Werner 2010 Meat Sci 2010 Werner C, Natter R, Schellander K, Wicke M (2010) Mitochondrial respiratory activity in porcine longissimus muscle fibers of different pig genetics in relation to their meat quality. Meat Sci 85:127-33. Skeletal muscle Pig
Benani 2009 J Neurosci Methods 2009 Benani A, Barquissau V, Carneiro L, Salin B, Colombani A-L, Leloup C, Casteilla L, Rigoulet M, Pénicaud L (2009) Method for functional study of mitochondria in rat hypothalamus. J Neurosci Methods 178:301-7. Nervous system Rat
Anderson 2009 J Am Coll Cardiol 2009 Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8. Heart Human
Larsen 2009 Diabetologia 2009 Larsen S, Ara I, Rabøl R, Andersen JL, Boushel RC, Dela F, Helge JW (2009) Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes? Diabetologia 52:1400-8. Skeletal muscle Human
Scheibye-Knudsen 2009 Eur J Appl Physiol 2009 Scheibye-Knudsen M, Quistorff B (2009) Regulation of mitochondrial respiration by inorganic phosphate: comparing permeabilized muscle fibers and isolated mitochondria prepared from type-1 and type-2 rat skeletal muscle. Eur J Appl Physiol 105:279-87. Skeletal muscle Rat
Anderson 2009 J Clin Invest 2009 Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81. Skeletal muscle Human
Mouse
Rat
Raboel 2009 J Clin Endocrinol Metabol 2009 Rabøl R, Højberg PM, Almdal T, Boushel R, Haugaard SB, Madsbad S, Dela F (2009) Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes. J Clin Endocrinol Metabol 94:1372-78. Skeletal muscle Human
Jorgensen 2009 Am J Physiol Endocrinol Metab 2009 Jørgensen W, Gam C, Andersen JL, Schjerling P, Scheibye-Knudsen M, Mortensen OH, Grunnet N, Nielsen MO, Quistorff B (2009) Changed mitochondrial function by pre- and/or postpartum diet alterations in sheep. Am J Physiol Endocrinol Metab 297:E1349-57. Skeletal muscle Other mammals
Rabol 2009 Diabetes Obes Metab 2009 Rabol R, Hojberg PM, Almdal T, Boushel RC, Haugaard SB, Madsbad S, Dela F (2009) Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes. Diabetes Obes Metab 11:355-60. Skeletal muscle Human
Casas 2009 PloS One 2009 Casas F, Pessemesse L, Grandemange S, Seyer P, Baris O, Gueguen N, Ramonatxo C, Perrin F, Fouret G, Lepourry L, Cabello G, Wrutniak-Cabello C (2009) Overexpression of the mitochondrial T3 receptor induces skeletal muscle atrophy during aging. PLoS One 4:e5631. Skeletal muscle Mouse
Sokolova 2009 BMC Cell Biol 2009 Sokolova N, Vendelin M, Birkedal R (2009) Intracellular diffusion restrictions in isolated cardiomyocytes from rainbow trout. BMC Cell Biol 10:90. Heart Rat Fishes
Scott 2009 Am J Physiol Regul Integr Comp Physiol 2009 Scott GR, Richards JG, Milsom WK (2009) Control of respiration in flight muscle from the high-altitude bar-headed goose and low-altitude birds. Am J Physiol Regul Integr Comp Physiol 297:R1066-74. Skeletal muscle Birds
Hickey 2009 Am J Physiol Cell Physiol 2009 Hickey AJ, Chai CC, Choong SY, de Freitas Costa S, Skea GL, Phillips AR, Cooper GJ (2009) Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts. Am J Physiol Cell Physiol 297:C766–74. Heart Rat
Rabol 2009 Metabolism 2009 Rabøl R, Svendsen PF, Skovbro M, Boushel RC, Haugaard SB, Schjerling P, Schrauwen P, Hesselink MK, Nilas L, Madsbad S, Dela F (2009) Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. Metabolism 58:1145-52. Skeletal muscle Human
Gnaiger 2009 Int J Biochem Cell Biol 2009 Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45. Skeletal muscle Human
Mouse
Gnaiger 2008 POS 2008
O2k-Protocols contents
Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial Dysfunction in Drug-Induced Toxicity (Dykens JA, Will Y, eds) John Wiley & Sons, Inc, Hoboken, NJ:327-52.
Blood cells Mouse
Wijers 2008 PLoS One 2008 Wijers SL, Schrauwen P, Saris WH, van Marken Lichtenbelt WD (2008) Human skeletal muscle mitochondrial uncoupling is associated with cold induced adaptive thermogenesis. PLoS One 3:e1777. Skeletal muscle Human
Schneeberger 2008 Shock 2008 Schneeberger S, Kuznetsov AV, Seiler R, Renz O, Meusburger H, Mark W, Brandacher G, Margreiter R, Gnaiger E (2008) Mitochondrial ischemia-reperfusion injury of the transplanted rat heart: improved protection by preservation versus cardioplegic solutions. Shock 30:365-71. Heart Rat
Casas 2008 PLoS One 2008 Casas F, Pessemesse L, Grandemange S, Seyer P, Gueguen N, Baris O, Lepourry L, Cabello G, Wrutniak-Cabello C (2008) Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber types. PLoS One 3:e2501. Skeletal muscle Mouse
Pacheco 2008 Master Thesis 2008 Pacheco S (2008) The effect of cryopreservation on mitochondrial function in human skeletal muscle. Master Thesis:66 pp. Skeletal muscle
Nervous system
Human
Rat
Juellig 2008 Proteomics 2008 Jüllig M, Hickey AJ, Chai CC, Skea GL, Middleditch MJ, Costa S, Choong SY, Philips AR, Cooper GJ (2008) Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics 8:2556-72. Heart Rat
Konieczny 2008 J Cell Biol 2008 Konieczny P, Fuchs P, Reipert S, Kunz WS, Zeöld A, Fischer I, Paulin D, Schröder R, Wiche G (2008) Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms. J Cell Biol 181:667-81. Skeletal muscle Mouse
Garcia-Roves 2008 J Biol Chem 2008 Garcia-Roves PM, Osler ME, Holmstroem MH, Zierath JR (2008) Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem 283:35724-34. Skeletal muscle
Gruno 2008 J Gastroenterol 2008 Gruno M, Peet N, Tein A, Salupere R, Sirotkina M, Valle J, Peetsalu A, Seppet EK (2008) Atrophic gastritis: deficient complex I of the respiratory chain in the mitochondria of corpus mucosal cells. J Gastroenterol 43:780-8. Endothelial;epithelial;mesothelial cell Human
Aragones 2008 Nat Genet 2008 Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, K Harten S, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 40:170-80. Skeletal muscle Mouse
Kuhnt 2007 Neurochem Res 2007 Kuhnt T, Pelz T, Qu X, Haensgen G, Dunst J, Gellerich FN (2007) Mitochondrial OXPHOS functions in R1H rhabdomyosarcoma and skeletal muscles of the rat. Neurochem Res 32:973–80. Skeletal muscle Rat
Huetter 2007 Aging Cell 2007 Hütter E, Skovbro M, Lener B, Prats C, Rabol R, Dela F, Jansen-Dürr P (2007) Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation in aged human skeletal muscle. Aging Cell 6:245-56. Skeletal muscle Human
Pasdois 2007 J Mol Cell Cardiol 2007 Pasdois P, Beauvoit B, Costa AD, Vinassa B, Tariosse L, Bonoron-Adèle S, Garlid KD, Dos Santos P (2007) Sarcoplasmic ATP-sensitive potassium channel blocker HMR1098 protects the ischemic heart: implication of calcium, complex I, reactive oxygen species and mitochondrial ATP-sensitive potassium channel. J Mol Cell Cardiol 42:631-42. Heart Human
Boushel 2007 Diabetologia 2007 Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6. Skeletal muscle Human
Pasdois 2007 Am J Physiol Heart Circ Physiol 2007 Pasdois P, Quinlan CL, Rissa A, Tariosse L, Vinassa B, Costa AD, Pierre SV, Dos Santos P, Garlid KD (2007) Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS. Am J Physiol Heart Circ Physiol 292:H1470-8. Heart Rat
Favory 2006 Am J Respir Crit Care Med 2006 Favory R, Lancel S, Tissier S, Mathieu D, Decoster B, Nevière R (2006) Myocardial dysfunction and potential cardiac hypoxia in rats induced by carbon monoxide inhalation. Am J Respir Crit Care Med 174:320-25. Heart Human
Rat
Pasdois 2006 J Bioenerg Biomembr 2006 Pasdois P, Beauvoit B, Tariosse L, Vinassa B, Bonoron-Adèle S, Santos PD (2006) MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart. J Bioenerg Biomembr 38:101-12. Heart Rat
Guerrero 2005 Am J Physiol Regul Integr Comp Physiol 2005 Guerrero K, Wuyam B, Mezin P, Vivodtzev I, Vendelin M, Borel JC, Hacini R, Chavanon O, Imbeaud S, Saks V, Pison C (2005) Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise training in lung transplant skeletal muscle. Am J Physiol Regul Integr Comp Physiol 289:R1144-54. Skeletal muscle Human
Winkler-Stuck 2005 J Neural Transm 2005 Winkler-Stuck K, Kirches E, Mawrin C, Dietzmann K, Lins H, Wallesch CW, Kunz WS, Wiedemann FR (2005) Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson's disease. J Neural Transm 112:499-518. Skeletal muscle Human
Gueguen 2005 J Physiol 2005 Gueguen N, Lefaucheur L, Ecolan P, Fillaut M, Herpin P (2005) Ca2+-activated myosin-ATPases, creatine and adenylate kinases regulate mitochondrial function according to myofibre type in rabbit. J Physiol 564:723-35. Skeletal muscle Rabbit
Seppet 2005 Mol Cell Biochem 2005 Seppet E, Eimre M, Peet N, Paju K, Orlova E, Ress M, Kovask S, Piirsoo A, Saks VA, Gellerich FN, Zierz S, Seppet EK (2005) Compartmentation of energy metabolism in atrial myocardium of patients undergoing cardiac surgery. Mol Cell Biochem 270:49-61. Heart Human
Oezen 2005 Hum Mol Genet 2005 Oezen I, Rossmanith W, Forss-Petter S, Kemp S, Voigtlander T, Moser-Thier K, Wanders RJ, Bittner RE, Berger J (2005) Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency. Hum Mol Genet 14:1127-37. Skeletal muscle
Nervous system
Fibroblast Human
Mouse
Anmann 2005 FEBS J 2005 Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet EK, Saks VA (2005) Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J 272:3145-61. Heart Rat
Opalka 2004 Br Poult Sci 2004 Opalka JR, Wicke M, Gellerich FN, Schmidt R, Rosner F, Zierz S, von Lengerken G (2004) Mitochondrial function in turkey skeletal muscle - impact on meat quality. Br Poult Sci 45:367-79. Skeletal muscle Birds
Traufeller 2004 Biochim Biophys Acta 2004 Traufeller K, Gellerich FN, Zierz S (2004) Different sensitivities of CPT I and CPT II for inhibition by L-aminocarnitine in human skeletal muscle. Biochim Biophys Acta 1608:149-54. Skeletal muscle
Liver
Human
Rat
Kraft 2004 Thesis Universität Halle-Wittenberg - Germany 2004 Kraft A (2004) Langzeitstabilität der Mitochondrienfunktion permeabilisierter Muskelfasern in der Diagnostik mitochondrialer Enzephalomyopathien. Thesis Universität Halle-Wittenberg - Germany 74pp. Skeletal muscle Human
Mayr 2004 Pediatr Res 2004 Mayr JA, Paul J, Pecina P, Kurnik P, Forster H, Fotschl U, Sperl W, Houstek J (2004) Reduced respiratory control with ADP and changed pattern of respiratory chain enzymes as a result of selective deficiency of the mitochondrial ATP synthase. Pediatr Res 55:988-94. Heart
Skeletal muscle
Fibroblast Human
Kuznetsov 2004 Am J Physiol Heart Circ Physiol 2004 Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Mark W, Steurer W, Saks V, Usson Y, Margreiter R, Gnaiger E (2004) Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am J Physiol Heart Circ Physiol 286:H1633–41. Heart Rat
Saks 2003 Biophys J 2003 Saks V, Kuznetsov A, Andrienko T, Usson Y, Appaix F, Guerrero K, Kaambre T, Sikk P, Lemba M, Vendelin M (2003) Heterogeneity of ADP diffusion and regulation of respiration in cardiac cells. Biophys J 84:3436-56. Heart Rat
Seppet 2003 Cardiac Remodeling and Failure 2003 Seppet E, Peet N, Paju K, Ress M, Saks V, Gellerich FN, Chen Y, Trumbeckaite S, Prondzinsky R, Silber R, Werdan K, Zierz S, Seppet EK (2003) Mitochondrial function in failing human myocardium in vitro: atrioventricular differences. In: Cardiac Remodeling and Failure (Singal P, Dixon I, Lorrie A. Kirshenbaum L, Dhalla N eds. Kiuwer Academic Publishers, Boston: 459-470. Heart Human
Gnaiger 2003 Adv Exp Med Biol 2003 Gnaiger E (2003) Oxygen conformance of cellular respiration. A perspective of mitochondrial physiology. Adv Exp Med Biol 543:39-55. Heart
Liver
Endothelial;epithelial;mesothelial cell
Fibroblast Human
Rat
Andrienko 2003 J Exp Biol 2003 Andrienko T, Kuznetsov AV, Kaambre T, Usson Y, Orosco A, Appaix F, Tiivel T, Sikk P, Vendelin M, Margreiter R, Saks VA (2003) Metabolic consequences of functional complexes of mitochondria, myofibrils and sarcoplasmic reticulum in muscle cells. J Exp Biol 206:2059-72. Heart Rat
Wenchich 2003 Physiol Res 2003 Wenchich L, Drahota Z, Honzík T, Hansíková H, Tesarová M, Zeman J, Houstek J (2003) Polarographic evaluation of mitochondrial enzymes activity in isolated mitochondria and in permeabilized human muscle cells with inherited mitochondrial defects. Physiol Res 52:781-88. Skeletal muscle Human
Kuznetsov 2003 Anal Biochem 2003 Kuznetsov AV, Kunz WS, Saks V, Usson Y, Mazat J-P, Letellier T, Gellerich FN, Margreiter R (2003) Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers. Anal Biochem 319:296-303. Heart
Skeletal muscle
Human
Kudin 2002 Mol Biol Rep 2002 Kudin A, Vielhaber S, Elger CE, Kunz WS (2002) Differences in flux control and reserve capacity of cytochrome c oxidase (COX) in human skeletal muscle and brain suggest different metabolic effects of mild COX deficiencies. Mol Biol Rep 29:89-92. Skeletal muscle
Nervous system
Human
Opalka 2002 Biochem Pharmacol 2002 Opalka JR, Gellerich FN, Kling L, Müller-Beckmann B, Zierz S (2002) Effect of the new matrix metalloproteinase inhibitor RO-28-2653 on mitochondrial function. Biochem Pharmacol 63:725-32. Heart Rat
Gellerich 2002 Biochim Biophys Acta (Vol 1556) 2002 Gellerich FN, Deschauer M, Chen Y, Müller T, Neudecker S, Zierz S (2002) Mitochondrial respiratory rates and activities of respiratory chain complexes correlate linearly with heteroplasmy of deleted mtDNA without threshold and independently of deletion size. Biochim Biophys Acta 1556:41-52. Skeletal muscle Human
Varlamov 2002 Hum Mol Genet 2002 Varlamov DA, Kudin AP, Vielhaber S, Schroder R, Sassen R, Becker A, Kunz D, Haug K, Rebstock J, Heils A, Elger CE, Kunz WS (2002) Metabolic consequences of a novel missense mutation of the mtDNA CO I gene. Hum Mol Genet 11:1797-805. Skeletal muscle Human
Kuznetsov 2002 Anal Biochem 2002 Kuznetsov AV, Strobl D, Ruttmann E, Königsrainer A, Margreiter R, Gnaiger E (2002) Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem 305:186-94. Liver Pig
Braun 2001 Biochim Biophys Acta 2001 Braun U, Paju K, Eimre M, Seppet E, Orlova E, Kadaja L, Trumbeckaite S, Gellerich FN, Zierz S, Jockusch H, Seppet EK (2001) Lack of dystrophin is associated with altered integration of the mitochondria and ATPases in slow-twitch muscle cells of MDX mice. Biochim Biophys Acta 1505:258-70. Heart
Skeletal muscle
Mouse
Menin 2001 Mol Cell Biochem 2001 Menin L, Panchichkina M, Keriel C, Olivares J, Braun U, Seppet EK, Saks VA (2001) Macrocompartmentation of total creatine in cardiomyocytes revisited. Mol Cell Biochem 220:149-59. Heart
Seppet 2001 Biochim Biophys Acta 2001 Seppet EK, Kaambre T, Sikk P, Tiivel T, Vija H, Tonkonogi M, Sahlin K, Kay L, Appaix F, Braun U, Eimre M, Saks VA (2001) Functional complexes of mitochondria with Ca,Mg ATPases of myofibrils and sarcoplasmic reticulum in muscle cells. Biochim Biophys Acta 1504:379-95. Skeletal muscle Human
Saks 2001 Biochem J 2001 Saks VA, Kaambre T, Sikk P, Eimre M, Orlova E, Paju K, Piirsoo A, Appaix F, Kay L, Regitz-Zagrosek V, Fleck E, Seppet E (2001) Intracellular energetic units in red muscle cells. Biochem J 356:643-57. Heart
Skeletal muscle
Trumbeckaite 2001 Eur J Biochem 2001 Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN (2001) Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. Eur J Biochem 268:1422-9. Heart
Skeletal muscle
Rabbit
Saks 2000 Acta Physiol Scand 2000 Saks VA, Kongas O, Vendelin M, Kay L (2000) Role of the creatine/phosphocreatine system in the regulation of mitochondrial respiration. Acta Physiol Scand 168:635-41. Heart Mouse
Vielhaber 2000 Biochem Soc Trans 2000 Vielhaber S, Kudin A, Schroder R, Elger CE, Kunz WS (2000) Muscle fibres: applications for the study of the metabolic consequences of enzyme deficiencies in skeletal muscle. Biochem Soc Trans 28:159-64. Skeletal muscle Human
Gnaiger 2000 Life in the Cold 2000
O2k-Protocols contents
Gnaiger E, Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Steurer W, Margreiter R (2000) Mitochondria in the cold. In: Life in the Cold (Heldmaier G, Klingenspor M, eds) Springer, Heidelberg, Berlin, New York:431-42.
Heart Rat
Kunz 2000 J Biol Chem 2000 Kunz WS, Kudin A, Vielhaber S, Elger CE, Attardi G, Villani G (2000) Flux control of cytochrome c oxidase in human skeletal muscle. J Biol Chem 275:27741-5. Skeletal muscle Human
Appaix 2000 Biochim Biophys Acta 2000 Appaix F, Minatchy M-N, Riva-Lavieille C, Olivares J, Antonsson B, Saks VA (2000) Rapid spectrophotometric method for quantitation of cytochrome c release from isolated mitochondria or permeabilized cells revisited. Biochim Biophys Acta 1457:175-81. Heart
Kay 2000 J Biol Chem 2000 Kay L, Nicolay K, Wieringa B, Saks V, Wallimann T (2000) Direct evidence for the control of mitochondrial respiration by mitochondrial creatine kinase in oxidative muscle cells in situ. J Biol Chem 275:6937-44. Skeletal muscle Mouse
Kuznetsov 1999 Transplant Proc 1999 Kuznetsov AV, Brandacher G, Steurer W, Margreiter R, Gnaiger E (1999) Estimation of mitochondrial damage in heart preservation. Transplant Proc 31:992. Heart Rat
Vielhaber 1999 J Neurol Sci 1999 Vielhaber S, Winkler K, Kirches E, Kunz D, Büchner M, Feistner H, Elger CE, Ludolph AC, Riepe MW, Kunz WS (1999) Visualization of defective mitochondrial function in skeletal muscle fibers of patients with sporadic amyotrophic lateral sclerosis. J Neurol Sci 169:133-9. Skeletal muscle
Nervous system
Human
Saks 1998 Mol Cell Biochem 1998 Saks VA, Veksler VI, Kuznetsov AV, Kay L, Sikk P, Tiivel T, Tranqui L, Olivares J, Winkler K, Wiedemann F, Kunz WS (1998) Permeabilised cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem 184:81-100. Skeletal muscle
Kuznetsov 1998 BTK 1998 Kuznetsov AV, Lassnig B, Margreiter R, Gnaiger E (1998) Diffusion limitation of oxygen versus ADP in permeabilized muscle fibers. In BioThermoKinetics in the Post Genomic Era (Larsson C, Påhlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:273-6. Heart
Skeletal muscle
Rat
Wiedemann 1998 J Neurol Sci 1998 Wiedemann FR, Winkler K, Kuznetsov AV, Bartels C, Vielhaber S, Feistner H, Kunz WS (1998) Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. J Neurol Sci 156:65-72. Skeletal muscle Human
Wiedemann 1998 FEBS Lett 1998 Wiedemann FR, Kunz WS (1998) Oxygen dependence of flux control of cytochrome c oxidase – implications for mitochondrial diseases. FEBS Lett 422:33-5. Skeletal muscle Mouse
Kuznetsov 1997 Biochim Biophys Acta 1997 Kuznetsov AV, Winkler K, Kirches E, Lins H, Feistner H, Kunz WS (1997) Application of inhibitor titrations for the detection of oxidative phosphorylation defects in saponin-skinned muscle fibers of patients with mitochondrial diseases. Biochim Biophys Acta 1360:142-50. Skeletal muscle
Sperl 1997 Mol Cell Biochem 1997 Sperl W, Skladal D, Gnaiger E, Wyss M, Mayr U, Hager J, Gellerich FN (1997) High resolution respirometry of premeabilized skeletal muscle fibers in the diagnosis of neuromuscular disorders. Mol Cell Biochem 174:71-8. Skeletal muscle Human
Kirches 1996 Saponin 1996 Kirches E, Winkler K, Kuznetsov AV, Lins H, von Bossanyi P, Dietzmann K, Frank B, Feistner H, Kunz WS (1996) Laserfluoreszenz-Studien der Mitochondrienfunktion in Saponin-permeabilisierten Skelettmuskelfasern von Patienten mit chronisch progressiver externer Ophthalmoplegie. Jahrb Neuromusk Erkrankungen 1996, Arcis Verlag:166-9. Skeletal muscle Human
O´Gorman 1996 Biochim Biophys Acta 1996 O'Gorman E, Beutner G, Wallimann T, Brdiczka D (1996) Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain. Biochim Biophys Acta 1276:161-70. Heart
Skeletal muscle
Nervous system
Rat
Kuznetsov 1996 J Biol Chem 1996 Kuznetsov AV, Clark JF, Winkler K, Kunz WS (1996) Increase of flux control of cytochrome c oxidase in copper-deficient mottled brindled mice. J Biol Chem 271:283-8. Heart
Skeletal muscle
Mouse
Gellerich 1995 HRR 1995 Gellerich FN, Skladal D, Schranzhofer R, Lanznaster N, Kunz WS, Wisniewski E, Kuznetsov A, Krishmer M, Gnaiger E, Margreiter R, Sperl W (1995) Hochauflösende Respirometrie und multiple Substrat/Inhibitor-Titration zum funktionellen Nachweis mitochondrialer Defekte in permeabilisierten Muskelfasern. In: Molekulare Grundlage hereditärer Myopathien. (Gross M, Gresser U, Hrsg), Zuckschwerdt Verlag, München, Bern, Wien, New York:52-66. Skeletal muscle Human
Wisniewski 1995 Eur J Biochem 1995 Wisniewski E, Gellerich FN, Kunz WS (1995) Distribution of flux control among the enzymes of mitochondrial oxidative phosphorylation in calcium-activated saponin-skinned rat musculus soleus fibers. Eur J Biochem 230:549-54. Skeletal muscle Rat
Winkler 1995 Biochim Biophys Acta 1995 Winkler K, Kuznetsov AV, Lins H, Kirches E, von Bossanyi P, Dietzmann K, Frank B, Feistner H, Kunz WS (1995) Laser-excited fluorescence studies of mitochondrial function in saponin-skinned skeletal muscle fibers of patients with chronic progressive external ophthalmoplegia. Biochim Biophys Acta 1272:181-4. Skeletal muscle Human
Skladal 1994 BTK-268 1994
BTK1994
Skladal D, Sperl W, Schranzhofer R, Krismer M, Gnaiger E, Margreiter R, Gellerich FN (1994) Preservation of mitochondrial functions in human skeletal muscle during storage in high energy preservation solution (HEPS). In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:268-71.
Skeletal muscle Human
Kunz 1994 Anal Biochem 1994 Kunz WS, Kuznetsov AV, Winkler K, Gellerich FN, Neuhof S, Neumann HW (1994) Measurement of fluorescence changes of NAD(P)H and fluorescent flavoproteins in saponin-skinned fibers. Anal Biochem 216:322-7. Skeletal muscle Human
Khuchua 1994 Biochim Biophys Acta 1994 Khuchua ZA, Kuznetsov AV, Schild L, Neumann HW, Kunz WS (1994) The influence of caffeine and Ca2+ on oxidative phosphorylation in saponin-skinned human skeletal muscle fibers. Biochim Biophys Acta 1188:373-9. Skeletal muscle Human
Gellerich 1994 BTK-263 1994
BTK1994
Gellerich FN, Steinlechner R, Wyss M, Eberl T, Müller LC, Skladal D, Sperl W, Dapunt O, Margreiter R, Gnaiger E (1994) Mitochondrial function in the atrial appendage of the human heart. Characterization by high-resolution respirometry. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:263-7.
Heart Human
Sperl 1994 J Inher Metab Dis 1994 Sperl W, Skladal D, Lanznaster N, Schranzhofer R, Zaunschirm G, Gnaiger E, Gellerich FN (1994) Polarographic studies of saponin-skinned muscle fibers in patients with mitochondrial myopathies. J Inher Metab Dis 17:307-10. Skeletal muscle Human
Kunz 1993 FEBS Lett 1993 Kunz WS, Kuznetsov AV, Gellerich FN (1993) Mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers is stimulated by caffeine. FEBS Lett 323:188-90. Skeletal muscle Human
Kunz 1993 Biochim Biophys Acta 1993 Kunz WS, Kuznetsov AV, Schulze W, Eichhorn K, Schild L, Striggow F, Bohnensack R, Grasshoff H, Neumann HW, Gellerich FN (1993) Functional characterization of mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers. Biochim Biophys Acta 1144:46-53. Skeletal muscle Human


O2k-Publications in the MiPMap

O2k-Publications: Permeabilized tissue - Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.
Was submitted in year Tissue and cell Cell line Mammal and model Nonmammal
Soendergaard 2016 Abstract IOC109 2016 Skeletal muscle Human
Chicco 2016b Abstract MitoFit Science Camp 2016 2016 Skeletal muscle Human
Chicco 2016a Abstract MitoFit Science Camp 2016 2016 Heart
Skeletal muscle
Mouse
Gnaiger 2016 UMDF2016 2016 Endothelial;epithelial;mesothelial cell
Genital
Fibroblast
Other cell lines
Gnaiger 2015 Abstract MiPschool Cape Town 2015 2015
Ehinger 2015 Abstract MiPschool London 2015 2015 Heart
Blood cells
Fibroblast Human
Ost 2015 Abstract IOC100 2015 Skeletal muscle Fibroblast Mouse
Brown 2015 Abstract MiPschool Cape Town 2015 2015 Heart Rat
Zhang 2015 Abstract MiPschool Greenville 2015 2015 Skeletal muscle Mouse
Laner 2015 Abstract MiPschool Greenville 2015 2015 Skeletal muscle Dog
Laner 2015 Abstract MiP2015 2015 Skeletal muscle Dog
Galina 2015 Abstract MiP2015 2015 Skeletal muscle Rat
Bhattarai 2015 Abstract MiPschool Greenville 2015 2015 Skeletal muscle Human
Ojuka 2015 Abstract MiPschool Cape Town 2015 2015
George 2015 Abstract MiPschool Cape Town 2015 2015 Skeletal muscle Rat
Spendiff 2014 Abstract MiP2014 2014 Skeletal muscle Human
Larsen 2014 Abstract MiP2014 2014 Skeletal muscle
Fat
Human
Porter 2014 Abstract IOC95 2014 Skeletal muscle Human
Herbst 2014 Abstract MiP2014 2014 Nervous system Mouse
Shaikh 2014 Circulation 2014 Heart Rat
Brown DA 2014 Abstract MiP2014 2014 Heart Rat
Kane 2014 Abstract MiP2014 2014 Skeletal muscle Rat
Mracek 2014 Abstract MiP2014 2014 Heart Human
Burtscher 2014 Abstract MiP2014 2014 Nervous system Mouse
Perry 2014 Abstract MiP2014 2014 Skeletal muscle Human
Laner 2014 Abstract MiP2014 2014 Skeletal muscle Dog
Coen 2014 Abstract MiP2014 2014 Skeletal muscle Human
Schoepf 2014 Abstract MiP2014 2014 Genital Human
Neufer 2014 Abstract MiP2014 2014 Skeletal muscle Mouse
Doerrier 2014 Abstract SECF 2014 Heart Mouse
Maedo 2014 Abstract IOC 2014-04 Schroecken 2014 Endothelial;epithelial;mesothelial cell Human
Kandashvili 2014 Abstract MiP2014 2014 Endothelial;epithelial;mesothelial cell Human
Hickey 2014 Abstract MiP2014 2014 Heart Rat
Sparks 2014 Abstract MiP2014 2014 Skeletal muscle Mouse
Volt 2014 Abstract The 2014 Ageing Summit 2014 Heart Mouse
Hepple 2014 Abstract MiP2014 2014 Skeletal muscle Human
Boushel 2013 Abstract MiP2013 2013 Skeletal muscle Human
Larsen S 2013 Abstract MiP2013 2013 Skeletal muscle
Fat
Human
Votion 2013 Abstract MiP2013 2013 Skeletal muscle Horse
Chicco 2013 Abstract MiP2013 2013 Skeletal muscle Human
Other mammals
Lundby 2013 Abstract MiP2013 2013 Skeletal muscle Human
Cavalcanti de Albuquerque 2013 Abstract MiP2013 2013 Skeletal muscle Rat
Fernandez-Vizarra 2013 Abstract IOC80 2013 Heart
Skeletal muscle
Nervous system
Liver
Kidney
HEK
HeLa
Neuroblastoma
Fibroblast
Other cell lines
Human
Mouse
Holloway 2013 Abstract MiP2013 2013 Heart
Skeletal muscle
Rat
Hickey 2013 Abstract MiP2013 2013 Heart Other mammals Fishes
Oliveira MF 2013 Abstract MiP2013 2013 Skeletal muscle Neuroblastoma Human
Drosophila
Hexapods
Other invertebrates
Gnaiger 2013 Abstract MiP2013 2013 Skeletal muscle Human
Gnaiger 2013 Abstract Mito2013 2013 Skeletal muscle Human
Dela 2013 Abstract MiP2013 2013 Skeletal muscle Human
Garcia-Roves 2013 Abstract MiP2013 2013 Skeletal muscle
Nervous system
Liver
Islet cell;pancreas;thymus
Fat
Mouse
Irving 2013 Abstract MiP2013 2013 Skeletal muscle
Liver
Fat
Mouse
Darveau 2013 Abstract MiP2013 2013 Skeletal muscle Hexapods
Pichaud 2013 Abstract MiP2013 2013 Skeletal muscle Drosophila Hexapods
Jacobs 2013 Abstract MiP2013 2013 Skeletal muscle Human
Dzialowski 2013 Abstract MiP2013 2013 Skeletal muscle Birds
Slinde 2013 Abstract MiP2013 2013 Heart
Liver
Blood cells
Other mammals Fishes
Gnaiger 2013 Abstract Neurocon Kolkata 2013 Skeletal muscle Human
Kotwica 2013 Abstract MiP2013 2013 Heart
Skeletal muscle
Mouse
Tepp 2013 Abstract MiP2013 2013 Heart Rat
Lemieux 2013 Abstract MiP2013 2013 Heart
Skeletal muscle
Rat
Hedges IBEC2012 2012 Skeletal muscle Mouse
Irving 2012 Abstract IOC72 2012 Skeletal muscle
Nervous system
Liver
Fat
Mouse
Rat
Hoppel 2012 Abstract Bioblast 2012 Skeletal muscle
Liver
Human
Mark 2012 Abstract Bioblast 2012 Heart
Liver
Fishes
Le 2012 Abstract Bioblast 2012 Skeletal muscle Human
Doerrier 2012 Abstract Bioblast 2012 Heart Mouse
Hepple 2012 Abstract Bioblast 2012 Skeletal muscle
Towheed 2012 Abstract IOC72 2012 Drosophila Hexapods
Distefano 2012 Abstract IOC68 2012 Skeletal muscle Human
Holloway 2012 Abstract Bioblast 2012 Skeletal muscle Rat
Pesta 2011Abstract Mitochondrial Medicine-Diagnosis 2011 Human
Pesta 2011Abstract Mitochondrial Medicine-Training 2011 Skeletal muscle Human
Chu SRS 2011 2011 Liver Mouse
Dela MiP2010 2010 Human
Garedew 2006 Biochim Biophys Acta 2006 Heart Mouse
Lemieux 2006 Biochim Biophys Acta 2006 Heart Mouse


mt-Preparations

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