O2k-Publications: Homogenate

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O2k-Publications: Homogenate

O2k-Publications in the MiPMap

»O2k-Publications: Topics

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 Was published in yearReferenceOrganismTissue;cell
MiPNet21.06 SUIT RP2016-08-17
O2k-Protocols
SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Scialo 2016 PLOS ONE2016Scialo F, Sriram A, Stefanatos R, Sanz A (2016) Practical recommendations for the use of the GeneSwitch Gal4 system to knock-Down genes in Drosophila melanogaster. PLOS ONE 11:e0161817.Drosophila
Kontro 2016 Thesis2016Kontro H (2016) Mitochondrial function and sirtuin expression in hippocampus of young and old high and low-capacity runner rats. Master's Thesis p35.RatNervous system
Ejaz 2016 Diabetes2016Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C (2016) Dietary betaine supplementation increases Fgf21 levels to improve glucose homeostasis and reduce hepatic lipid accumulation in mice. Diabetes 65:902-12.MouseFat
Peleli 2016 Free Radic Biol Med2016Peleli M, Zollbrecht C, Montenegro MF, Hezel M, Zhong J, Persson EG, Holmdahl R, Weitzberg E, Lundberg JO, Carlström M (2016) Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis. Free Radic Biol Med 99:472-84.MouseLiver
Strifler 2016 PLOS ONE2016Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363.RatLiver
Karlsson 2016 Shock2016Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E (2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10.MouseNervous system
Liver
Rohlenova 2016 Antioxid Redox Signal2016Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2high breast cancer. Antioxid Redox Signal 26:84-103.Human
Mouse
Liver
Genital
Other cell lines
Torres 2016 Redox Biol2016Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72.Human
Mouse
Nervous system
Liver
Endothelial;epithelial;mesothelial cell
Fibroblast
Scialo 2016 Cell Metab2016Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A (2016) Mitochondrial ROS produced via reverse electron transport extend animal lifespan. Cell Metab 23:725-34.Drosophila
Nissinen 2016 Sci Rep2016Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695.MouseSkeletal muscle
De Carvalho 2016 J Cell Biochem2016de Carvalho AK, da Silva S, Serafini E, de Souza DR, Farias HR, de Bem Silveira G, Silveira PC, de Souza CT, Portela LV, Muller AP (2016) Prior exercise training prevent hyperglycemia in STZ mice by increasing hepatic glycogen and mitochondrial function on skeletal muscle. J Cell Biochem 118:678-85.MouseSkeletal muscle
Liver
Heinonen 2016 Hum Exp Toxicol2016Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol [Epub ahead of print].PigHeart
Strifler 2016b PLOS ONE2016Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682.RatLiver
MiPNet21.13 Comparison mt-preparations2016
O2k-Protocols
O2k-Protocols: Mitochondrial preparations for HRR.
MouseHeart
Salin 2016 Physiol Biochem Zool2016Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23.Skeletal muscle
Liver
Boutant 2016 Cell Rep2016Boutant M, Kulkarni SS, Joffraud M, Raymond F, Métairon S, Descombes P, Cantó C (2016) SIRT1 gain of function does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75.MouseSkeletal muscle
Liver
Fat
Kilbaugh 2016 Mitochondrion2016Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25.PigNervous system
Pokkunuri 2016 Oxid Med Cell Longev2016Pokkunuri I, Ali Q, Asghar M (2016) Grape powder improves age-related decline in mitochondrial and kidney functions in Fischer 344 rats. Oxid Med Cell Longev ID 6135319:8p.RatKidney
Witt 2016 Metab Brain Dis2016Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis [Epub ahead of print].RatNervous system
Yavari 2016 Cell Metab2016Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of γ2 AMPK induces obesity and reduces β cell function. Cell Metab 23:821-36.MouseNervous system
Melenovsky 2016 Eur J Heart Fail2016Melenovsky V, Petrak J, Mracek T, Benes J, Borlaug BA, Nuskova H, Pluhacek T, Spatenka J, Kovalcikova J, Drahota Z, Kautzner J, Pirk J, Houstek J (2016) Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. Eur J Heart Fail [Epub ahead of print].HumanHeart
Chu 2016 World J Gastroenterol2016Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84.RatLiver
Salin 2016 Physiol Rep2016Salin K, Villasevil EM, Auer SK, Anderson GJ, Selman C, Metcalfe NB, Chinopoulos C (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiol Rep 10.14814/phy2.13007.FishesLiver
Sobotka 2016 J Bioenerg Biomembr2016Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.Mouse
Rat
Liver
Valek 2016 Redox Biol2016Valek L, Häussler A, Dröse S, Eaton P, Schröder K, Tegeder I (2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91.MouseNervous system
Uecal 2016 J Neurotrauma2016Üçal M, Kraitsy K, Weidinger A, Paier-Pourani J, Patz S, Fink B, Molcanyi M, Schäfer U (2016) Comprehensive profiling of modulation of nitric oxide levels and mitochondrial activity in the injured brain: an experimental study based on the fluid percussion injury model in rats. J Neurotrauma 34:475-86.RatNervous system
Strifler 2016 Magyar Sebeszet2016Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8.RatLiver
O2k versus multiwell respirometer2015-10-05
Logo OROBOROS INSTRUMENTS.jpg
O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis.
HumanFibroblast
MiPNet18.10 O2k versus multiwell2015-10-05
OROBOROS
O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis.
HumanFibroblast
MiPNet17.03 Shredder vs Fibres2015-06-18
O2k-Protocols
Mitochondrial respiration in permeabilized fibres versus homogenate from fish liver and heart. An application study with the PBI-Shredder.
FishesHeart
Liver
MiPNet18.05 Amplex-Mouse-heart2015-06-16
O2k-Protocols
O2k-Fluorometry: HRR and H2O2 production in mouse cardiac tissue homogenate.
MouseHeart
MiPNet20.13 Safranin mt-membranepotential2015-06-15
O2k-Protocols
O2k-Fluorometry: HRR and simultaneous determination of mt-membrane potential with safranin.
MouseNervous system
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Boutant 2015 Mol Metab2015Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2015) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.MouseFat
Liver
Skeletal muscle
Jing 2015 Int J Biol Sci2015Jing L, He MT, Chang Y, Mehta SL, He QP, Zhang JZ, Li PA (2015) Coenzyme Q10 protects astrocytes from ROS-induced damage through inhibition of mitochondria-mediated cell death pathway. Int J Biol Sci 11:59-66.MouseNervous system
Other cell lines
Koliaki 2015 Cell Metab2015Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46.HumanLiver
Jiroutkova 2015 Crit Care2015Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448.HumanSkeletal muscle
Hasli 2015 Master Thesis2015Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147.FishesHeart
Skeletal muscle
Weidinger 2015 Antioxid Redox Signal2015Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.RatLiver
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.
Human
Mouse
Heart
Nervous system
HEK
Errea 2015 J Neuroinflammation2015Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152.MouseNervous system
Bonhoure 2015 Genes Dev2015Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM1 (2015) Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev 29:934-47.MouseLiver
Roy Chowdhury 2015 Biosci Rep2015Roy Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36.MouseNervous system
Drechsler 2015 Intensive Care Medicine Experimental2015Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.MouseLiver
Kidney
Kilbaugh 2015 J Am Heart Assoc2015Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently Altered Brain Mitochondrial Bioenergetics After Apparently Successful Resuscitation From Cardiac Arrest. J Am Heart Assoc 4(9) pii: e002232.PigNervous system
Ziak 2015 Mitochondrion2015Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.HumanSkeletal muscle
Rovenko 2015 Comp Biochem Physiol A Mol Integr Physiol2015Rovenko BM, Kubrak OI, Gospodaryov DV, Yurkevych IS, Sanz A, Lushchak OV, Lushchak VI (2015) Restriction of glucose and fructose causes mild oxidative stress independently of mitochondrial activity and reactive oxygen species in Drosophila melanogaster. Comp Biochem Physiol A Mol Integr Physiol 187:27-39.Drosophila
Sobotka 2015 Physiol Res2015Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.RatLiver
Syrjanen 2015 Front Zool2015Syrjanen L, Valanne S, Kuuslahti M, Tuomela T, Sriram A, Sanz A, Jacobs HT, Ramet M, Parkkila S. (2015) β carbonic anhydrase is required for female fertility in Drosophila melanogaster. Front Zool 12:19.Drosophila
Kluckova 2015 Methods Mol Biol2015Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94.MouseEndothelial;epithelial;mesothelial cell
Genital
Other cell lines
Kilbaugh 2015 Exp Neurol2015Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144.PigNervous system
Hollis 2015 Proc Natl Acad Sci U S A2015Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.RatNervous system
Chu 2015 Liver Transpl2015Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.RatLiver
Canto 2015 Curr Protoc Mouse Biol2015Cantó C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.MouseHeart
Skeletal muscle
Nervous system
Liver
Fat
Abou-Hamdan 2015 Methods Enzymol2015Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28.Human
Pig
Mouse
Rat
Heart
Nervous system
Liver
Kidney
Genital
CHO
Neuroblastoma
Fibroblast
Kilbaugh 2015 PLoS One2015Kilbaugh TJ, Lvova M, Karlsson M, Zhang Z, Leipzig J, Wallace DC, Margulies SS (2015) Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. PLoS One 10:e0130927.PigNervous system
Lauritzen 2015 Am J Physiol Heart Circ Physiol2015Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015) Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. Am J Physiol Heart Circ Physiol 309:H434-49.MouseHeart
Beauchamp 2015 Biosci Rep2015Beauchamp B, Thrush AB, Quizi J, Antoun G, McIntosh N, Al-Dirbashi OY, Patti ME, Harper ME (2015) Undernutrition during pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring. Biosci Rep 35. pii:e00200.MouseHeart
Liver
Burtscher 2015 Mitochondrion2015Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.MouseNervous system
Flatters 2015 Prog Mol Biol Transl Sci2015Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.RatNervous system
Ryu 2014 Cell Metab2014Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J (2014) A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. Cell Metab 20:856-69.MouseHeart
Nervous system
Liver
Lung;gill
Krumschnabel 2014 Methods Enzymol2014
O2k-Protocols contents
Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81.
MouseNervous system
Kivelae 2014 EMBO Mol Med2014Kivelä R, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21.RatHeart
Larsen 2014 Anal Biochem2014Larsen S, Kraunsøe R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8.Human
Mouse
Skeletal muscle
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.MouseLiver
Koenemann 2014 Dissertation2014Koenemann B (2014) Einfluss der Hyperglykämie auf die mitochondriale Atmung von Leberzellen septischer Mäuse mit und ohne Imeglimin. PhD Thesis 1-61.MouseLiver
Chausse 2014 Endocrinology2014Chausse B, Solon C, Caldeira da Silva CC, Masselli Dos Reis IG, Manchado-Gobatto FB, Gobatto CA, Velloso LA, Kowaltowski AJ (2014) Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating. Endocrinology 9:e97673.RatSkeletal muscle
Den Hollander 2014 Toxicol Sci2014den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31.MouseNervous system
Chu 2014 Liver Transpl2014Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2014) Mitochondrial dysfunction in rat steatotic liver is due to a defect in Complex-I making them more susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.RatLiver
Gnaiger 2014 MitoPathways2014
O2k-Protocols
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. OROBOROS MiPNet Publications, Innsbruck:80 pp.
Human
Mouse
Heart
Skeletal muscle
Fibroblast
Kemppainen 2014 Hum Mol Genet2014Kemppainen KK, Rinne J, Sriram A, Lakanmaa M, Zeb A, Tuomela T, Popplestone A, Singh S, Sanz A, Rustin P, Jacobs HT (2014) Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency. Hum Mol Genet 23:2078-93.Drosophila
Drahota 2014 Physiol Res2014Drahota Z, Palenickova E, Endlicher R, Milerova M, Brejchova J, Vosahlikova M, Svoboda P, Kazdova L, Kalous M, Cervinkova Z, Cahova M (2014) Biguanides inhibit complex I, II and IV of rat liver mitochondria and modify their functional properties. Physiol Res 63:1-11.RatLiver
Pham 2014 Am J Physiol2014Pham T, Loiselle D, Power A, Hickey AJ (2014) Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Am J Physiol 307:C499–507.RatHeart
Tufi 2014 Nat Cell Biol2014Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM (2014) Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. Nat Cell Biol 16:157-66.Drosophila
Karlsson 2013 Int J Biochem Cell Biol2013Karlsson M, Hempel C, Sjövall F, Hansson Magnus J, Kurtzhals JA, Elmér E (2013) Brain mitochondrial function in a murine model of cerebral malaria and the therapeutic effects of rhEPO. Int J Biochem Cell Biol 45:151-5.MouseNervous system
Aidt 2013 PLoS Curr2013Aidt FH, Nielsen SM, Kanters J, Pesta D, Nielsen TT, Nørremølle A, Hasholt L, Christiansen M, Hagen CM (2013) Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model. PLoS Curr 5. pii:ecurrents.hd.d8917b4862929772c5a2f2a34ef1c201.MouseNervous system
Holm 2013 PLoS One2013Holm T, Brøgger-Jensen MR, Johnson L, Kessel L (2013) Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One 8:e79620.RatEndothelial;epithelial;mesothelial cell
Hara 2013 Eur J Anaesthesiol2013Hara N, Karlsson M, Sjövall F, Hansson Magnus J, Elmér E, Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112.MouseNervous system
Trumbeckaite 2013 Mitochondrion2013Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN (2013) Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801. Mitochondrion 13:539–47.RatNervous system
De Castro IP 2013 Cell Death Dis2013de Castro IP, Costa AC, Celardo I, Tufi R, Dinsdale D, Loh SH, Martins LM (2013) Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants. Cell Death Dis 24:e873.Drosophila
Schneeberger 2013 Cell2013Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87.MouseNervous system
Goo 2013 Clin Exp Pharmacol Physiol2013Goo S, Pham T, Han JC, Nielsen P, Taberner A, Hickey A, Loiselle D (2013) Multiscale measurement of cardiac energetics. Clin Exp Pharmacol Physiol 40:671-81.Heart
Hernandez-Alvarez 2013 Antioxid Redox Signal2013Hernández-Alvarez MI, Paz JC, Sebastián D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A (2013) Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal 19:366-78.RatLiver
Other cell lines
Kiebish 2012 J Biol Chem2012Kiebish MA, Yang K, Sims HF, Jenkins CM, Liu X, Mancuso DJ, Zhao Z, Guan S, Abendschein DR, Han X, Gross RW (2012) Myocardial regulation of lipidomic flux by cardiolipin synthase: Setting the beat for bioenergetic efficiency. J Biol Chem 287:25086-97.MouseHeart
Kucera 2012 J Gastroenterol Hepatol2012Kucera O, Rousar T, Stankova P, Hanackova L, Lotkova H, Podhola M, Cervinkova Z (2012) Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. J Gastroenterol Hepatol 27:323-30.RatLiver
Palenickova 2011 Physiol Res2011Palenickova E, Cahova M, Drahota Z, Kazdova L, Kalous M (2011) Inhibitory effect of metformin on oxidation of NADH-dependent substrates in rat liver homogenate. Physiol Res 60:835-9.RatLiver
Benes 2011 Clin Sci (Lond)2011Benes J, Kazdova L, Drahota Z, Houstek J, Medrikova D, Kopecky J, Kovarova N, Vrbacky M, Sedmera D, Strnad H, Kolar M, Petrak J, Benada O, Skaroupkova P, Cervenka L, Melenovsky V (2011) Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats. Clin Sci (Lond) 121:29-41.RatHeart
Pecinova 2011 Mitochondrion2011Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8.RatHeart
Nervous system
Liver
Kidney
Niehusmann 2011 Epilepsy Behav2011Niehusmann P, Surges R, von Wrede RD, Elger CE, Wellmer J, Reimann J, Urbach H, Vielhaber S, Bien CG, Kunz WS (2011) Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery. Epilepsy Behav 20:38-43.HumanSkeletal muscle
Nervous system
Hench 2011 PloS One2011Hench J, Bratic Hench I, Pujol C, Ipsen S, Brodesser S, Mourier A, Tolnay M, Frank S, Trifunovic A (2011) A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. PloS One 6:e28417.Caenorhabditis elegans
Nematodes
Thomas 2011 Mitochondrion2011Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr (2011) Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18.Human
Mouse
Heart
Skeletal muscle
Nervous system
Fibroblast
Mancuso 2010 J Biol Chem2010Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW (2010) Genetic ablation of calcium-independent phospholipase A2{gamma} prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation. J Biol Chem 285:36495-510.MouseFat
Skeletal muscle
Duvigneau 2010 Shock2010Duvigneau JC, Kozlov AV, Zifko C, Postl A, Hartl RT, Miller I, Gille L, Staniek K, Moldzio R, Gregor W, Haindl S, Behling T, Redl H, Bahrami Sl (2010) Reperfusion does not induce oxidative stress but sustained endoplasmic reticulum stress in livers of rats subjected to traumatic/hemorrhagic shock. Shock 33:289-98.RatLiver
Nilsson 2010 Thesis2010Nilsson I (2010) Hypothalmic regulation of food intake – focus on the anx/anx mouse. Thesis Karolinska Institute Stockholm, Department of Molecular Medicine and Sugery, 62 pp.MouseNervous system
Milaeva 2010 Bioinorg Chem Appl2010Milaeva ER, Filimonova SI, Meleshonkova NN, Dubova LG, Shevtsova EF, Bachurin SO, Zefirov NS (2010) Antioxidative activity of ferrocenes bearing 2,6-di-tert-butylphenol moieties. Bioinorg Chem Appl 165482. EpubRatNervous system
Liver
MiPNet14.05 TPP-mtMembranePotential2009-01
O2k-Protocols contents
TPP+ and mt-membrane potential.
MouseNervous system
Kudin 2002 Mol Biol Rep2002Kudin A, Vielhaber S, Elger CE, Kunz WS (2002) Differences in flux control and reserve capacity of cytochrome c oxidase (COX) in human skeletal muscle and brain suggest different metabolic effects of mild COX deficiencies. Mol Biol Rep 29:89-92.HumanSkeletal muscle
Nervous system
Debska 2001 Brain Res2001Debska G, May R, Kicinska A, Swewczyk A, Elger C, Kunz WS (2001) Potassium channel openers depolarize hippocampal mitochondria. Brain Res 892:42-50.RatNervous system
Kunz 1999 J Neurochem1999Kunz WS, Kuznetsov AV, Clark JF, Tracey I, Elger CE (1999) Metabolic consequences of the cytochrome c oxidase deficiency in brain of copper-deficient Movbr mice. J Neurochem 72:1580-5.MouseNervous system
O2k-Publications in the MiPMap

O2k-Publications: Homogenate - Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.
 ReferenceOrganismTissue;cell
Volani 2016 Abstract Mito Xmas Meeting InnsbruckEffects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.MouseLiver
Volani 2016 Abstract MitoFit Science Camp 2016Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.Mouse
Rat
Liver
Blood cells
Lymphocyte
Chicco 2016a Abstract MitoFit Science Camp 2016Oxygen dependence of H2O2 release from skeletal muscle and cardiac mitochondria: influence of sample preparation.MouseHeart
Skeletal muscle
Krumschnabel 2016a Abstract MitoFit Science Camp 2016O2k-Protocols: Mitochondrial preparations for HRR.MouseHeart
Krajcova 2016 Abstract MitoFit Science Camp 2016Mitochondrial pathogenesis of propofol infusion syndrome in an in vitro model of human skeletal muscle.HumanSkeletal muscle
Davies 2016 Abstract Proceedings of The Physiological SocietyDevelopment of mitochondrial function in the cortex and cerebellum of the ovine fetus.BovinesNervous system
Doerrier 2016 Abstract MitoFit Science Camp 2016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.Human
Mouse
Heart
Blood cells
HEK
Platelet
Markova 2016 Abstract MitoFit Science Camp 2016Porcine hearts samples preparation: PBI-Shredder or saponin?PigHeart
Nielsen 2016 Abstract IOC116Nielsen B, Woertwein G, Cejvanovic V, Hansen AR, Weimann A, Bjerring PN, Poulsen HE, Joergensen MB (2016) The function of mitochondria and oxidative stress after antidepressants treatment in rats. Mitochondr Physiol Network 21.11RatNervous system
Burtscher J 2016 Abstract MitoFit Science Camp 2016Oxidative phosphorylation in the healthy and epileptic mouse brain.MouseNervous system
Garcia-Souza 2016 Abstract Mito Xmas Meeting InnsbruckAssessment of fatty acid oxidation in mouse brain and liver mitochondria.Nervous system
Liver
Hoppel 2016b Abstract MitoFit Science Camp 2016Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects.HumanSkeletal muscle
Weidgang 2015 Abstract MiP2015Mitochondrial respiration in homogenized biopsies from kidney, liver, heart and diaphragm from mice after blunt thoracic trauma and hemorrhagic shock. Effects of a novel hydrogen sulfide donor AP39.MouseHeart
Skeletal muscle
Liver
Kidney
Devaux 2015 Abstract MiP2015Mitochondrial complexes I and II behave differently in two anoxia-tolerant species: adaptive mitochondrial plasticity may be related to the ability to undergo metabolic depression.FishesNervous system
Renshaw 2015 Abstract MiP2015Mitochondrial responses to thermal stress: is the ability to withstand anoxia-induced stress associated with cross-tolerance to thermal stress?FishesNervous system
Gnaiger 2015 Abstract MiPschool Cape Town 2015The functional design of the electron transfer system: substrate control of mitochondrial respiration.
Volani 2015 Abstract IOC106Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.Human
Mouse
Heart
Liver
Blood cells
Lymphocyte
Ali 2015 Abstract MiP2015Mitochondrial function and ROS homeostasis in young mouse heart and brain: the sex factor!MouseHeart
Nervous system
Lindquist 2015 Abstract IOC106Alteraas EK, Lindquist C, Berge RK, Bjorndal B (2015) OXPHOS capacity in mouse liver altered by modified fatty acids that inhibit or stimulate beta-oxidation. Mitochondr Physiol Network 20.10.MouseLiver
Sleiman 2015 Abstract MiP2015Mitochondrial respiration in sequential biospies from skeletal muscles during hemorrhagic shock and over the course of 48h of reperfusion in pigs.PigSkeletal muscle
Krumschnabel 2014 Abstract MiP2014Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.MouseNervous system
Sobotka 2014 Abstract IOC95Sobotka O (2014) Effect of α-Tocopheryl succinate on Complex II. Mitochondr Physiol Network 19.10RatHeart
Liver
Garcia-Roves 2013 Abstract MiP2013Garcia-Roves PM, Gonzalez-Franquesa A, Martinez-Navarro L, Fernandez-Ruiz R (2013) Metabolic flexibility before and after lifestyle intervention in a diet-induced type 2 diabetes animal model. Mitochondr Physiol Network 18.08.MouseFat
Islet cell;pancreas;thymus
Liver
Nervous system
Skeletal muscle
Ortiz 2013 Abstract SEORMolecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.Rat
Laner 2013 ASMRMLaner V, Gradl P, Eigentler A, Fontana-Ayoub M, Fasching M, Gnaiger E (2013) The OROBOROS Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis. ASMRM2013.MouseHeart
Hand 2013 Abstract MiP2013Hand SC, Patil Y (2013) Defense against ATP depletion during the energy-limited state of diapause. Mitochondr Physiol Network 18.08.Artemia
Crustaceans
Matallo 2013 Abstract MiP2013Matallo J, Gröger M, Wagner K, Wagner F, Radermacher P, Calzia E (2013) Effects of mechanical ventilation after blunt chest trauma on diaphragmatic mitochondrial respiration in chronically cigarette smoke exposed mice: A clinically relevant model? Mitochondr Physiol Network 18.08.MouseHeart
Lung;gill
Skeletal muscle
Oliveira MF 2013 Abstract MiP2013Oliveira MF (2013) Comparative mitochondrial physiology in blood feeding insect vectors and parasites. Mitochondr Physiol Network 18.08.Human
Drosophila
Hexapods
Other invertebrates
Skeletal muscle
Neuroblastoma
Prouteau-Angebault 2013 Abstract IOC75Prouteau-Angebault C (2013) Are cardiolipins involved in the mitochondrial respiratory chain defect in OPA1 mouse model? Mitochondr Physiol Network 18.03.MouseSkeletal muscle
Nervous system
Krumschnabel 2013 Abstract MiP2013Krumschnabel G, Eigentler A, Fontana-Ayoub M, Draxl A, Fasching M, Gnaiger E (2013) Tissue homogenates for respiratory OXPHOS analysis in comparative mitochondrial physiology: mouse and trout – heart and liver. Mitochondr Physiol Network 18.08.Mouse
Fishes
Heart
Nervous system
Liver
Irving 2013 Abstract MiP2013Irving BA, Stahl R, Kane CJ, Chernousov M, Argyropoulos G, Carey D (2013) Sex differences in murine mitochondrial oxidative capacity following a 24 week high-fat diet. Mitochondr Physiol Network 18.08.MouseSkeletal muscle
Liver
Fat
Pecina 2013 Abstract MiP2013Pecina P, Houšťková H, Mráček T, Pecinová A, Nůsková H, Tesařová M, Hansíková H, Janota J, Zeman J, Houštěk J (2013) The use of lymphocytes for diagnostics of mitochondrial oxidative phosphorylation disorders. Mitochondr Physiol Network 18.08.HumanBlood cells
Lymphocyte
Eigentler 2012 Abstract BioblastEigentler A, Draxl A, Fontana-Ayoub M, Gnaiger E (2012) The PBI-Shredder - an auxiliary HRR-tool for the preparation of tissue homogenates for diagnosis of mitochondrial respiratory function. Mitochondr Physiol Network 17.12.MouseHeart
Nervous system
Liver
Burtscher J 2012 Abstract BioblastBurtscher J, Eigentler A, Gnaiger E, Schwarzer C (2012) Mitochondrial function in the mouse hippocampus. Mitochondr Physiol Network 17.12.MouseNervous system
Cervinkova 2012 Abstract BioblastCervinkova Z, Stankova P, Cervinka M, Kucera O, Drahota Z (2012) Evaluation of mitochondrial functions – an important tool for experimental hepatology. Mitochondr Physiol Network 17.12.RatLiver
Horvath 2012 Abstract BioblastHorvath G, Eigentler A, Gnaiger E, Tretter L (2012) Respiratory substrate effects on mitochondrial membrane potential - experiments with mouse cardiac muscle homogenate. Mitochondr Physiol Network 17.12.MouseHeart
Hand 2012 Abstract BioblastPatil Y, Gnaiger E, Hand SC (2012) Respiration in embryo lysates reveals diminished Complex I activity and inhibition of the phosphorylation system during diapause in Artemia franciscana. Mitochondr Physiol Network 17.12.Artemia
Crustaceans
Labieniec-Watala 2012 Abstract BioblastLabieniec-Watala M, Siewiera K, Watala C (2012) Seasonal fluctuations affect the physiology of laboratory animals – facts and artifacts from the perspective of heart mitochondrial respiratory response to tested compounds. Mitochondr Physiol Network 17.12.Mouse
Rat
Heart
Liver
Fibroblast
Sumbalova 2012 Abstract BioblastSumbalova Z, Fasching M, Erich Gnaiger E (2012) Evaluation of mitochondrial respiration and membrane potential in mouse brain homogenate. Mitochondr Physiol Network 17.12:61.MouseNervous system
Sumbalova 2011 Abstract Mitochondrial MedicineSumbalova Z, Fasching M, Gnaiger E (2011) Substrate control in mitochondrial respiration and regulation of mitochondrial membrane potential. Abstract Mitochondrial Medicine Chicago.MouseNervous system
Pesta 2011Abstract Mitochondrial Medicine-DiagnosisPesta D, Wiethuechter A, Karall D, Schocke M, Gnaiger E (2011) Functional mitochondrial diagnosis in a patient suffering from sudden exercise intolerance. Abstract Mitochondrial Medicine Chicago.Human

mt-Preparations

 »O2k-Publications:_Topics#Preparations