Neufer PD

From Bioblast

Jump to: navigation, search


MITOEAGLE
e-COST MITOEAGLE
e-COST MITOEAGLE countries
MitoPedia
MiPsociety
MitoGlobal
COST Action MITOEAGLE         Working Groups         MITOEAGLE Events         Previous: Verona         Next: Barcelona         Short-Term Scientific Missions         Management Committee         Members    


Evolution-Age-Gender-Lifestyle-Environment  » COST Action CA15203 Mitochondrial fitness mapping

Neufer PD


MitoPedia topics: EAGLE 

COST: Member


Name Neufer P Darrell, Prof. Ph.D.

Director, East Carolina Diabetes and Obesity Institute

Professor, Departments of Exercise and Sport Science and Physiology

Institution
Darrell Neufer

Brody School of Medicine

East Carolina University

Address 115 Heart Drive, 4101 ECHI, 27834
City Greenville
State/Province North Carolina (NC)
Country USA
Email neuferp@ecu.edu
Weblink
O2k-Network Lab US NC Greenville Neufer PD


Labels: Field of research: Basic, Clinical 



Publications

Published Reference
Morad 2016 J Lipid Res 2016 Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42.
Ryan 2016 J Mol Cell Cardiol 2016 Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6.
Ryan 2016 Diabetes 2016 Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68.
Alleman 2016 Am J Physiol Heart Circ Physiol 2016 Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA (2016) Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol 310:H1360-70.
Gilliam 2016 Am J Physiol Endocrinol Metab 2016 Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301.
Ludzki 2015 Diabetes 2015 Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79.
Neufer 2015 Cell Metab 2015 Neufer PD, Bamman MM, Muoio DM, Bouchard C, Cooper DM, Goodpaster BH, Booth FW, Kohrt WM, Gerszten RE, Mattson MP, Hepple RT, Kraus WE, Reid MB, Bodine SC, Jakicic JM, Fleg JL, Williams JP, Joseph L, Evans M, Maruvada P, Rodgers M, Roary M, Boyce AT, Drugan JK, Koenig JI, Ingraham RH, Krotoski D, Garcia-Cazarin M, McGowan JA, Laughlin MR (2015) Understanding the cellular and molecular mechanisms of physical activity-induced health benefits. Cell Metab 22:4-11.
Brown 2014 J Cardiovasc Pharmacol Ther 2014 Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA (2014) Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther 19:121-32.
Ryan 2014 J Physiol 2014 Ryan TE, Brophy P, Lin CT, Hickner RC, Neufer PD (2014) Assessment of in vivo skeletal muscle mitochondrial respiratory capacity in humans by near-infrared spectroscopy: a comparison with in situ measurements. J Physiol 592:3231-41.
Perry 2013 Diabetes 2013 Perry CG, Kane DA, Lanza IR, Neufer PD (2013) Methods for assessing mitochondrial function in diabetes. Diabetes 62:1041-53.
Smith 2013 J Physiol 2013 Smith BK, Perry CG, Herbst EA, Ritchie IR, Beaudoin MS, Smith JC, Neufer PD, Wright DC, Holloway GP (2013) Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol. J Physiol 591:6089-101.
Gilliam 2013 Free Radic Biol Med 2013 Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD (2013) The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radic Biol Med 65:988-96.
Lin 2012 FASEB J 2012 Lin CT, Kelsey H, Fisher-Wellman KH, Perry CG, Kozy R, Lark DS, Gilliam LA, Smith CD, Neufer PD (2012) Low Intensity Exercise Attenuates Acute Lipid Loading-Induced Alterations in Mitochondrial Function in Rat Skeletal Muscle . FASEB J 1144.11.
Kwak 2012 Free Radic Biol Med 2012 Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207.
Perry 2012 J Physiol 2012 Perry CG, Kane DA, Herbst EA, Mukai K, Lark DS, Wright DC, Heigenhauser GJ, Neufer PD, Spriet LL, Holloway GP (2012) Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. J Physiol 590: 5475-5486.
Smith 2012 Biochem J 2012 Smith BK, Perry CG, Koves TR, Wright DC, Smith JC, Neufer PD, Muoio DM, Holloway GP (2012) Identification of a novel malonyl-CoA IC50 for CPT-I: implications for predicting in vivo fatty acid oxidation rates. Biochem J 448:13-20.
Kane 2011 Am J Physiol Endocrinol Metab 2011 Kane DA, Lin CT, Anderson EJ, Kwak HB, Cox JH, Brophy PM, Hickner RC, Neufer PD, Cortright RN (2011) Progesterone increases skeletal muscle mitochondrial H2O2 emission in non-menopausal women. Am J Physiol Endocrinol Metab 300:E528-35.
Perry 2011 Biochem J 2011 Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22.
Boyle 2011 Int J Obes 2011 Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA (2011) Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. Int J Obes 36:1025-31.
Kane 2010 Free Radic Biol Med 2010 Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7.
Anderson 2009 J Am Coll Cardiol 2009 Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8.
Anderson 2009 J Clin Invest 2009 Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81.


Abstracts

Published Reference
Neufer 2016 Abstract MitoFit Science Camp 2016 2016 Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers.
Kane 2016 Abstract MitoFit Science Camp 2016 2016 Effects of inhibiting myosin-ATPase on mitochondrial respiratory capacity in permeabilized skeletal muscle.
Terence 2015 Abstract MiPschool Greenville 2015 2015 Mitochondrial dysfunction is a genetic component of ischemic tissue pathology and occurs independent of differential blood flow in the murine limb.
Schmidt 2015 Abstract MiPschool Greenville 2015 2015 High-fat diet induced mitochondrial dysfunction exacerbates limb pathology in genetically ischemia protected mice.
Brown DA 2014 Abstract MiP2014 2014 The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes.
Neufer 2014 Abstract MiP2014 2014 Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O.
Perry 2014 Abstract MiP2014 2014 Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibres.
Shaikh 2014 Circulation 2014 Shaikh SR, Moukdar F, Alleman RJ, Lark DS, Neufer PD, Brown D (2014) The cardiolipin-targeting peptide Bendavia improves post-ischemic mitochondrial energetics by sustaining native respiratory protein complexes. Am Heart Assoc 130:A17592.


Participated at

Personal tools
Namespaces
Variants
Actions
OROBOROS
Bioblast
MitoGlobal
Support pages
Toolbox