MiPschool London 2015

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MiPschool London 2015

Publications in the MiPMap
MiPsociety

London UK, 2015 Apr 20-24. 8th MiPschool on Mitochondrial Physiology.

» http://mitochondria.cs.ucl.ac.uk/mip2015/?page_id=36

Mitochondrial Physiology Society (2015-04-20) MitoGlobal

Abstract: 8th MiPschool on Mitochondrial Physiology, 2015 Apr 20-24, London, UK.


Labels:






Additional: ORO, 2015 

Location: London, UK

Date: April 20-24, 2015

Organizers: Michael Duchen (University College London, United Kingdom), The MiPsociety. Email: m.duchen@ucl.ac.uk

Venue: Cruciform Building (WIBR), Lecture Theatre 2, UCL, London, UK

Website: MiPschool London 2015 by Gyorgy Szabadkai.

See also: 101st OROBOROS O2k-Workshop on high-resolution respirometry and O2k-Fluorometry, integrated in the 8th MiPschool, London 2015

Listed under MitoGlobal Events.
A picture of the group
Auditorium



Contents











Program

Speakers

Locations

Accomodation

Registration and Abstracts

Gallery

Impressions from London

London Eye, Big Ben and Houses of Parliament The Palace of Westminster St. Paul's Cathedral Albert Bridge


Impressions from the MiPschool in London 2015 (by Michael Duchen)

Erich Gnaiger Peter Rich Presentation.jpg Jphann Klare

Andrey Abramov Erich Gnaiger Presentation3.jpg Presentation4.jpg

Mike Murphy, Barry Halliwell, Michael Duchen Presentation6.jpg Presentation7.jpg Ian Holt

Nick Lane Michelangelo Campanella Presentation11.jpg Presentation12.jpg

Massimo Zeviani and Gyorgy Szabadkai The group is dining on the River Thames Shamima Rahman Presentation15.jpg

Johannes Ehinger Presentation22.jpg Working with the O2k Erich Gnaiger demonstrating the O2k

Erich Gnaiger demonstrating the O2k Presentation17.jpg Presentation18.jpg Andrew Hall


Recommended reading

A hard copy of this monograph on mitochondrial physiology will be included in the MiPschool material. It is available on-line free of charge and provides a background on OXPHOS analysis: From oxygen concentration to oxygen flux •• Membrane potential: electric and chemical forces •• Coupling and efficiency •• Biochemical thresholds •• Respiratory states •• MitoPathways to electron transfer complexes •• Normalization of mitochondrial respiration: coupling control and pathway control.


MiPschool London 2015: Abstracts

Presentation Session
Aryaman 2015 Abstract MiPschool London 2015 Modelling mitochondrial DNA variability in metabolism.
Barbieri 2015 Abstract MiPschool London 2015 Mitochondria remodelling in hypoxia.
Basso 2015 Abstract MiPschool London 2015 Parkin dependent regulation of ER-Mitochondia tethering via MFN ubiquitination.
Bentham 2015 Abstract MiPschool London 2015 Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes.
Cali 2015 Abstract MiPschool London 2015 Complementable green fluorescent protein based sensors of organelle proximity.
Chergova 2015 Abstract MiPschool London 2015 Role of the mitochondrial fission factor DRP1 in angiogenesis.
De Bari 2015 Abstract MiPschool London 2015 The mitochondrial metabolism of lactate isomers in human prostate cancer cells.
Dyrstad 2015 Abstract MiPschool London 2015 Activation of epithelial to mesenchymal transition (EMT) regulates stemness and metabolic reprogramming in mammary epithelial cells.
Ehinger 2015 Abstract MiPschool London 2015 Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease.
Fontes-Oliveira 2015 Abstract MiPschool London 2015 Metabolic alterations in laminin α2 chain-deficient muscle cells.
Gherardi 2015 Abstract MiPschool London 2015 The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo.
Glytsou 2015 Abstract MiPschool London 2015 Nitric oxide-associated 1 (NOA1) is part of the OPA1 complexes targeted during cell death.
Hill 2015 Abstract MiPschool London 2015 A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis.
Hoitzing 2015 Abstract MiPschool London 2015 What is the function of mitochondrial networks?
Hoppel 2015 Abstract MiPschool London 2015 Human blood cell types as study models of mitochondrial respiration and H2O2 production.
Johnston 2015 Abstract MiPschool London 2015 Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism.
Kovalcikova 2015 Abstract MiPschool London 2015 TMEM70 ablation leads to embryonic lethality in mouse knockout due to impairment of ATP synthase.
Logan 2015 Abstract MiPschool London 2015 Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling.
Manago 2015 Abstract MiPschool London 2015 Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species ad mitochondrial acid sphingomyelinase.
Matteo 2015 Abstract MiPschool London 2015 Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies.
Mussulini 2015 Abstract MiPschool London Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish.
Nardin 2015 Abstract MiPschool London 2015 Parkin translocation is triggered by its dephosporylation by calcineurin.
Nuskova 2015 Abstract MiPschool London 2015 Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies?
O'Sullivan 2015 Abstract MiPschool London 2015 Role of TFB1M-mediated 12S m62A ribosomal RNA methylation in m.1555A>G-related hearing loss.
Omori 2015 Abstract MiPschool London 2015 Exploring the role of growth factor and mitochondrial dynamics on prostatic development.
Pereira 2015 Abstract MiPschool London 2015 Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology.
Pettersen 2015 Abstract MiPschool London 2015 Metabolic adjustments after reversible induction of mitochondrial biogenesis via AMPK/NRF1 in HeLa cells.
Piel 2015 Abstract MiPschool London 2015 The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria.
Quintana-Cabrera 2015 Abstract MiPschool London 2015 Cristae remodeling by Opa1 modulates mitochondrial bioenergetics by promoting ATPase dimerization and activity.
Quirin 2015 Abstract MiPschool London 2015 Targeting Opa1 to increase mitochondria-dependent apoptosis of cancer cells.
Rousarova 2015 Abstract MiPschool London 2015 Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite.
Samardzic 2015 Abstract MiPschool London 2015 In vitro and in vivo study of the mitochondria shaping protein Opa1 in cancer.
Serafini 2015 Abstract MiPschool London 2015 Mitochondria-ER tethers: Identification by a FRET based high throughput screen.
Spadoni 2015 Abstract MiPschool London 2015 Mitochondria contribution to oxidative stress in fibroblasts isolated from patients affected by systemic sclerosis.
Sundier 2015 Abstract MiPschool London 2015 Mitochondrial ROS generation in cardiomyocyte reperfusion injury is modulated by succinate accumulation during ischaemia.
Template 2015 Abstract MiPschool London 2015
Valenti 2015 Abstract MiPschool London 2015 Different modulation of mitochondrial function by epigallocatechin-3 gallate in human disease: a matter of life and death.
Vecellio 2015 Abstract MiPschool London 2015 Identification and characterization of a novel MICU1 splicing variant.
Vrbova 2015 Abstract MiPschool London 2015 Acetaminophen conjugate induces mitochondria-related oxidative impairment in HK-2 cells.



Abstracts in the MiPMap

Sort all abstracts by MiPareas, species, tissues, respiratory states, diseases, ...

MiPMap - Areas: stress, diseases

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Has title Event MiP area Stress Diseases Respiration and regulation
Aryaman 2015 Abstract MiPschool London 2015 Modelling mitochondrial DNA variability in metabolism. mtDNA;mt-genetics ATP production
Barbieri 2015 Abstract MiPschool London 2015 Mitochondria remodelling in hypoxia. mt-Awareness Ischemia-reperfusion
Basso 2015 Abstract MiPschool London 2015 Parkin dependent regulation of ER-Mitochondia tethering via MFN ubiquitination. Parkinson's
Bentham 2015 Abstract MiPschool London 2015 Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes. Instruments;methods
mt-Biogenesis;mt-density
mtDNA;mt-genetics
mt-Medicine
Patients
mt-Awareness
Cancer
Cali 2015 Abstract MiPschool London 2015 Complementable green fluorescent protein based sensors of organelle proximity. Instruments;methods
Chergova 2015 Abstract MiPschool London 2015 Role of the mitochondrial fission factor DRP1 in angiogenesis. mt-Biogenesis;mt-density
De Bari 2015 Abstract MiPschool London 2015 The mitochondrial metabolism of lactate isomers in human prostate cancer cells. Cancer
Dyrstad 2015 Abstract MiPschool London 2015 Activation of epithelial to mesenchymal transition (EMT) regulates stemness and metabolic reprogramming in mammary epithelial cells. Fatty acid
Ehinger 2015 Abstract MiPschool London 2015 Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease. Instruments;methods
Fontes-Oliveira 2015 Abstract MiPschool London 2015 Metabolic alterations in laminin α2 chain-deficient muscle cells. Patients
Gherardi 2015 Abstract MiPschool London 2015 The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo. Calcium
Glytsou 2015 Abstract MiPschool London 2015 Nitric oxide-associated 1 (NOA1) is part of the OPA1 complexes targeted during cell death. mt-Structure;fission;fusion Cell death
Hill 2015 Abstract MiPschool London 2015 A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis. mt-Membrane Other
Hoitzing 2015 Abstract MiPschool London 2015 What is the function of mitochondrial networks? Instruments;methods
Hoppel 2015 Abstract MiPschool London 2015 Human blood cell types as study models of mitochondrial respiration and H2O2 production. Instruments;methods
Exercise physiology;nutrition;life style
Cryopreservation
Johnston 2015 Abstract MiPschool London 2015 Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism. Instruments;methods
mtDNA;mt-genetics
Developmental biology
Kovalcikova 2015 Abstract MiPschool London 2015 TMEM70 ablation leads to embryonic lethality in mouse knockout due to impairment of ATP synthase. Developmental biology
Patients
Cardiovascular ATP production
Logan 2015 Abstract MiPschool London 2015 Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling. Patients Calcium
Manago 2015 Abstract MiPschool London 2015 Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species ad mitochondrial acid sphingomyelinase. Patients Oxidative stress;RONS
Matteo 2015 Abstract MiPschool London 2015 Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies. Calcium
Mussulini 2015 Abstract MiPschool London Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish. Respiration
Instruments;methods
Patients
Other Substrate
Nardin 2015 Abstract MiPschool London 2015 Parkin translocation is triggered by its dephosporylation by calcineurin.
Nuskova 2015 Abstract MiPschool London 2015 Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies? mt-Membrane ATP production
O'Sullivan 2015 Abstract MiPschool London 2015 Role of TFB1M-mediated 12S m62A ribosomal RNA methylation in m.1555A>G-related hearing loss. mtDNA;mt-genetics
Patients
Aging;senescence
Omori 2015 Abstract MiPschool London 2015 Exploring the role of growth factor and mitochondrial dynamics on prostatic development.
Pereira 2015 Abstract MiPschool London 2015 Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology. mt-Medicine
Patients
Ischemia-reperfusion
Pettersen 2015 Abstract MiPschool London 2015 Metabolic adjustments after reversible induction of mitochondrial biogenesis via AMPK/NRF1 in HeLa cells. Instruments;methods
mt-Biogenesis;mt-density
mtDNA;mt-genetics
Substrate
Piel 2015 Abstract MiPschool London 2015 The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria. Patients Ischemia-reperfusion Cardiovascular
Quintana-Cabrera 2015 Abstract MiPschool London 2015 Cristae remodeling by Opa1 modulates mitochondrial bioenergetics by promoting ATPase dimerization and activity.
Quirin 2015 Abstract MiPschool London 2015 Targeting Opa1 to increase mitochondria-dependent apoptosis of cancer cells. Cell death Cyt c
Rousarova 2015 Abstract MiPschool London 2015 Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite. Oxidative stress;RONS
Samardzic 2015 Abstract MiPschool London 2015 In vitro and in vivo study of the mitochondria shaping protein Opa1 in cancer. mt-Structure;fission;fusion Cancer
Serafini 2015 Abstract MiPschool London 2015 Mitochondria-ER tethers: Identification by a FRET based high throughput screen. mt-Structure;fission;fusion
Spadoni 2015 Abstract MiPschool London 2015 Mitochondria contribution to oxidative stress in fibroblasts isolated from patients affected by systemic sclerosis. Patients Oxidative stress;RONS Other
Sundier 2015 Abstract MiPschool London 2015 Mitochondrial ROS generation in cardiomyocyte reperfusion injury is modulated by succinate accumulation during ischaemia. Patients Ischemia-reperfusion
Oxidative stress;RONS
Cardiovascular
Template 2015 Abstract MiPschool London 2015
Valenti 2015 Abstract MiPschool London 2015 Different modulation of mitochondrial function by epigallocatechin-3 gallate in human disease: a matter of life and death. Oxidative stress;RONS Cancer
Vecellio 2015 Abstract MiPschool London 2015 Identification and characterization of a novel MICU1 splicing variant. Calcium
Vrbova 2015 Abstract MiPschool London 2015 Acetaminophen conjugate induces mitochondria-related oxidative impairment in HK-2 cells.


MiPMap - States: coupling control, pathway control

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Has title Event MiP area Coupling states Pathways Respiration and regulation
Aryaman 2015 Abstract MiPschool London 2015 Modelling mitochondrial DNA variability in metabolism. mtDNA;mt-genetics ATP production
Barbieri 2015 Abstract MiPschool London 2015 Mitochondria remodelling in hypoxia. mt-Awareness
Basso 2015 Abstract MiPschool London 2015 Parkin dependent regulation of ER-Mitochondia tethering via MFN ubiquitination.
Bentham 2015 Abstract MiPschool London 2015 Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes. Instruments;methods
mt-Biogenesis;mt-density
mtDNA;mt-genetics
mt-Medicine
Patients
mt-Awareness
Cali 2015 Abstract MiPschool London 2015 Complementable green fluorescent protein based sensors of organelle proximity. Instruments;methods
Chergova 2015 Abstract MiPschool London 2015 Role of the mitochondrial fission factor DRP1 in angiogenesis. mt-Biogenesis;mt-density
De Bari 2015 Abstract MiPschool London 2015 The mitochondrial metabolism of lactate isomers in human prostate cancer cells. OXPHOS
Dyrstad 2015 Abstract MiPschool London 2015 Activation of epithelial to mesenchymal transition (EMT) regulates stemness and metabolic reprogramming in mammary epithelial cells. LEAK
ROUTINE
ETS
N
ROX
Fatty acid
Ehinger 2015 Abstract MiPschool London 2015 Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease. Instruments;methods N
S
Fontes-Oliveira 2015 Abstract MiPschool London 2015 Metabolic alterations in laminin α2 chain-deficient muscle cells. Patients
Gherardi 2015 Abstract MiPschool London 2015 The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo. Calcium
Glytsou 2015 Abstract MiPschool London 2015 Nitric oxide-associated 1 (NOA1) is part of the OPA1 complexes targeted during cell death. mt-Structure;fission;fusion
Hill 2015 Abstract MiPschool London 2015 A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis. mt-Membrane OXPHOS
ETS
Hoitzing 2015 Abstract MiPschool London 2015 What is the function of mitochondrial networks? Instruments;methods
Hoppel 2015 Abstract MiPschool London 2015 Human blood cell types as study models of mitochondrial respiration and H2O2 production. Instruments;methods
Exercise physiology;nutrition;life style
Johnston 2015 Abstract MiPschool London 2015 Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism. Instruments;methods
mtDNA;mt-genetics
Developmental biology
Kovalcikova 2015 Abstract MiPschool London 2015 TMEM70 ablation leads to embryonic lethality in mouse knockout due to impairment of ATP synthase. Developmental biology
Patients
ATP production
Logan 2015 Abstract MiPschool London 2015 Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling. Patients Calcium
Manago 2015 Abstract MiPschool London 2015 Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species ad mitochondrial acid sphingomyelinase. Patients
Matteo 2015 Abstract MiPschool London 2015 Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies. Calcium
Mussulini 2015 Abstract MiPschool London Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish. Respiration
Instruments;methods
Patients
ROUTINE
ETS
N
S
Substrate
Nardin 2015 Abstract MiPschool London 2015 Parkin translocation is triggered by its dephosporylation by calcineurin. ETS
Nuskova 2015 Abstract MiPschool London 2015 Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies? mt-Membrane ROUTINE
OXPHOS
ATP production
O'Sullivan 2015 Abstract MiPschool London 2015 Role of TFB1M-mediated 12S m62A ribosomal RNA methylation in m.1555A>G-related hearing loss. mtDNA;mt-genetics
Patients
Omori 2015 Abstract MiPschool London 2015 Exploring the role of growth factor and mitochondrial dynamics on prostatic development.
Pereira 2015 Abstract MiPschool London 2015 Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology. mt-Medicine
Patients
Pettersen 2015 Abstract MiPschool London 2015 Metabolic adjustments after reversible induction of mitochondrial biogenesis via AMPK/NRF1 in HeLa cells. Instruments;methods
mt-Biogenesis;mt-density
mtDNA;mt-genetics
N Substrate
Piel 2015 Abstract MiPschool London 2015 The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria. Patients
Quintana-Cabrera 2015 Abstract MiPschool London 2015 Cristae remodeling by Opa1 modulates mitochondrial bioenergetics by promoting ATPase dimerization and activity.
Quirin 2015 Abstract MiPschool London 2015 Targeting Opa1 to increase mitochondria-dependent apoptosis of cancer cells. Cyt c
Rousarova 2015 Abstract MiPschool London 2015 Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite. N
S
Samardzic 2015 Abstract MiPschool London 2015 In vitro and in vivo study of the mitochondria shaping protein Opa1 in cancer. mt-Structure;fission;fusion
Serafini 2015 Abstract MiPschool London 2015 Mitochondria-ER tethers: Identification by a FRET based high throughput screen. mt-Structure;fission;fusion
Spadoni 2015 Abstract MiPschool London 2015 Mitochondria contribution to oxidative stress in fibroblasts isolated from patients affected by systemic sclerosis. Patients
Sundier 2015 Abstract MiPschool London 2015 Mitochondrial ROS generation in cardiomyocyte reperfusion injury is modulated by succinate accumulation during ischaemia. Patients N
S
Template 2015 Abstract MiPschool London 2015
Valenti 2015 Abstract MiPschool London 2015 Different modulation of mitochondrial function by epigallocatechin-3 gallate in human disease: a matter of life and death. OXPHOS
Vecellio 2015 Abstract MiPschool London 2015 Identification and characterization of a novel MICU1 splicing variant. Calcium
Vrbova 2015 Abstract MiPschool London 2015 Acetaminophen conjugate induces mitochondria-related oxidative impairment in HK-2 cells.


MiPMap - Comparative: species, tissue and cells, preparation

»Help

Has title Event Organism Tissue and cell Preparation Enzyme
Aryaman 2015 Abstract MiPschool London 2015 Modelling mitochondrial DNA variability in metabolism.
Barbieri 2015 Abstract MiPschool London 2015 Mitochondria remodelling in hypoxia.
Basso 2015 Abstract MiPschool London 2015 Parkin dependent regulation of ER-Mitochondia tethering via MFN ubiquitination. Drosophila
Bentham 2015 Abstract MiPschool London 2015 Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes.
Cali 2015 Abstract MiPschool London 2015 Complementable green fluorescent protein based sensors of organelle proximity.
Chergova 2015 Abstract MiPschool London 2015 Role of the mitochondrial fission factor DRP1 in angiogenesis. Human
Mouse
Endothelial;epithelial;mesothelial cell
HUVEC
De Bari 2015 Abstract MiPschool London 2015 The mitochondrial metabolism of lactate isomers in human prostate cancer cells. Human Genital Homogenate
Isolated mitochondria
Dyrstad 2015 Abstract MiPschool London 2015 Activation of epithelial to mesenchymal transition (EMT) regulates stemness and metabolic reprogramming in mammary epithelial cells. Human Endothelial;epithelial;mesothelial cell
Other cell lines
Ehinger 2015 Abstract MiPschool London 2015 Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease. Human Heart
Blood cells
Fibroblast
Intact cells
Permeabilized tissue
Complex I
Fontes-Oliveira 2015 Abstract MiPschool London 2015 Metabolic alterations in laminin α2 chain-deficient muscle cells. Mouse Skeletal muscle
Gherardi 2015 Abstract MiPschool London 2015 The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo. Skeletal muscle
Glytsou 2015 Abstract MiPschool London 2015 Nitric oxide-associated 1 (NOA1) is part of the OPA1 complexes targeted during cell death.
Hill 2015 Abstract MiPschool London 2015 A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis. Mouse Liver Isolated mitochondria
Hoitzing 2015 Abstract MiPschool London 2015 What is the function of mitochondrial networks?
Hoppel 2015 Abstract MiPschool London 2015 Human blood cell types as study models of mitochondrial respiration and H2O2 production. Human Blood cells Intact cells
Johnston 2015 Abstract MiPschool London 2015 Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism. Mouse
Kovalcikova 2015 Abstract MiPschool London 2015 TMEM70 ablation leads to embryonic lethality in mouse knockout due to impairment of ATP synthase. Mouse Heart
Liver
Logan 2015 Abstract MiPschool London 2015 Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling. Human Endothelial;epithelial;mesothelial cell
Fibroblast
Manago 2015 Abstract MiPschool London 2015 Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species ad mitochondrial acid sphingomyelinase. Protists Intact cells
Isolated mitochondria
Matteo 2015 Abstract MiPschool London 2015 Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies. Mouse Skeletal muscle
Other cell lines
Intact cells
Mussulini 2015 Abstract MiPschool London Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish. Zebrafish Nervous system Intact organ
Nardin 2015 Abstract MiPschool London 2015 Parkin translocation is triggered by its dephosporylation by calcineurin.
Nuskova 2015 Abstract MiPschool London 2015 Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies? Human HEK
O'Sullivan 2015 Abstract MiPschool London 2015 Role of TFB1M-mediated 12S m62A ribosomal RNA methylation in m.1555A>G-related hearing loss. Blood cells
Fibroblast
Lymphocyte
Omori 2015 Abstract MiPschool London 2015 Exploring the role of growth factor and mitochondrial dynamics on prostatic development. Human Genital
Pereira 2015 Abstract MiPschool London 2015 Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology. Rat Heart Intact organ
Pettersen 2015 Abstract MiPschool London 2015 Metabolic adjustments after reversible induction of mitochondrial biogenesis via AMPK/NRF1 in HeLa cells.
Piel 2015 Abstract MiPschool London 2015 The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria. Rat Heart Isolated mitochondria
Quintana-Cabrera 2015 Abstract MiPschool London 2015 Cristae remodeling by Opa1 modulates mitochondrial bioenergetics by promoting ATPase dimerization and activity. Mouse Fibroblast
Quirin 2015 Abstract MiPschool London 2015 Targeting Opa1 to increase mitochondria-dependent apoptosis of cancer cells.
Rousarova 2015 Abstract MiPschool London 2015 Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite. Rat Liver
Kidney
Isolated mitochondria
Samardzic 2015 Abstract MiPschool London 2015 In vitro and in vivo study of the mitochondria shaping protein Opa1 in cancer. Mouse Other cell lines
Serafini 2015 Abstract MiPschool London 2015 Mitochondria-ER tethers: Identification by a FRET based high throughput screen.
Spadoni 2015 Abstract MiPschool London 2015 Mitochondria contribution to oxidative stress in fibroblasts isolated from patients affected by systemic sclerosis. Endothelial;epithelial;mesothelial cell
Fibroblast
Sundier 2015 Abstract MiPschool London 2015 Mitochondrial ROS generation in cardiomyocyte reperfusion injury is modulated by succinate accumulation during ischaemia. Mouse
Rat
Heart Intact cells
Template 2015 Abstract MiPschool London 2015
Valenti 2015 Abstract MiPschool London 2015 Different modulation of mitochondrial function by epigallocatechin-3 gallate in human disease: a matter of life and death. Endothelial;epithelial;mesothelial cell
Vecellio 2015 Abstract MiPschool London 2015 Identification and characterization of a novel MICU1 splicing variant. Skeletal muscle
Nervous system
HeLa
Vrbova 2015 Abstract MiPschool London 2015 Acetaminophen conjugate induces mitochondria-related oxidative impairment in HK-2 cells. Human Other cell lines
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