MiPschool Cape Town 2015

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MiPschool Cape Town 2015

Publications in the MiPMap

Cape Town ZA, 2015 Mar 24-28. 7th MiPschool on Mitochondrial Physiology, March 2015: "Reaching the world".

» http://www.mitochondrialphysiology2015.co.za

Mitochondrial Physiology Society (2015-03-24) MitoGlobal

Abstract: Abstracts are listed here in the frame of the MiPMap for the 7th MiPschool on Mitochondrial Physiology, 2015 Mar 24-28, Cape Town, ZA.

Labels: Additional: ORO, 2015 

Location: Cape Town, South Africa

Date: March 24-28, 2015

Organizer: Edward Ojuka (University of Cape Town, South Africa), The MiPsociety. Email: edward.ojuka@uct.ac.za

Venue: Southern Sun, Newlands

Official website: MiPschool_Cape_Town


 » MiPschool Cape Town 2015 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ...*
 » Siddiqah George - newly appointed OROBOROS O2k-Network Manager in South Africa. Online article by the University of Cape Town: 2015-05-26

Abstracts - alphabetical order

Presentation Session
Abdel-Rahman 2015 Abstract MiPschool Cape Town 2015 Assessment of NADPH-dependent oxygen consumption and hydrogen peroxide production by high-resolution respirometry and EPR spectroscopy.
Ali 2015 Abstract MiPschool Cape Town 2015 Early gender-related dimorphism in heart and brain mitochondria function and ROS dynamics.
Bajpeyi 2015 Abstract MiPschool Cape Town 2015 Twelve weeks of pioglitazone treatment improves insulin sensitivity, lipid utilization and metabolic flexibility - but not maximal ATP synthesis rates.
Bezuidenhout 2015 Abstract MiPschool Cape Town 2015 A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle.
Borutaite 2015 Abstract MiPschool Cape Town 2015 Mitochondria and regulation of cell death during ischemia.
Brown 2015 Abstract MiPschool Cape Town 2015 Protection of post-ischemic mitochondrial bioenergetics by targeting cardiolipin-dependent membrane fluidity.
Esterhuizen 2015 Abstract MiPschool Cape Town 2015 Metabolomics reveal altered mitochondrial metabolism associated with hypertension in a black South African male cohort: the SABPA study.
Fourie 2015 Abstract MiPschool Cape Town 2015 The association of Coenzyme Q10-deficiencies and respiratory chain disorders in South African patients.
George 2015 Abstract MiPschool Cape Town 2015 Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats.
Gnaiger 2015 Abstract MiPschool Cape Town 2015 The functional design of the electron transfer system: substrate control of mitochondrial respiration.
Gnaiger 2015 Abstract MiPschool Cape Town 2015 II On coupling control of mitochondrial respiration. What is wrong with the RCR?
Govender 2015 Abstract MiPschool Cape Town 2015 Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: The protective role of melatonin.
Huisamen 2015 Abstract MiPschool Cape Town 2015 The ATM protein and myocardial mitochondria.
Khan 2015 Abstract MiPschool Cape Town 2015 Bioenergetic Health Index profiling: step towards personalized medicine.
Kohn 2015 Abstract MiPschool Cape Town 2015 Are Cape Peninsula baboons raiding their way to obesity and type II diabetes?
Kriel 2015 Abstract MiPschool Cape Town 2015 Quantification of mitochondrial fission and fusion rate through photoactivation in Glioblastoma Multiforme.
Laner 2015 Abstract MiPschool Cape Town 2015 The OROBOROS Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis.
Loos 2015 Abstract MiPschool Cape Town 2015 SR-SIM, FRET and photo-activation: imaging autophagy and cell death in cell biology.
Louw 2015 Abstract MiPschool Cape Town 2015 Metabolomics investigation of South African children with respiratory chain deficiencies.
Maarman 2015 Abstract MiPschool Cape Town 2015 Characterisation of mitochondrial function in a model of pulmonary hypertension-induced right ventricular failure.
Madlala 2015 Abstract MiPschool Cape Town 2015 Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-β1.
Meldau 2015 Abstract MiPschool Cape Town 2015 Mitochondrial molecular diagnostics in South Africa: Lessons from the past 20 years.
Mendham 2015 Abstract MiPschool Cape Town 2015 Cycling and small-sided games similarly stimulates mitochondrial gene expression and signalling in middle-aged sedentary men.
Ojuka 2015 Abstract MiPschool Cape Town 2015 Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation.
Okanda 2015 Abstract MiPschool Cape Town 2015 Hyperlactatemia and mtDNA polymerase - gene mutations in HIV infected Zulu patients on stavudine-based HAART.
Pretorius 2015 Abstract MiPschool Cape Town 2015 Metallothioneins are involved in mitochondrial function and disease.
Schoonen 2015 Abstract MiPschool Cape Town 2015 Nuclear gene variants associated with complex I of the respiratory chain in Southern African children diagnosed with RCDs.
Template 2015 Abstract MiPschool Cape Town 2015
Van Dyk 2015 Abstract MiPschool Cape Town 2015 Optimization of selected cell lines for use on the Seahorse extracellular flux analyzer.
Van der Westhuizen 2015 Abstract MiPschool Cape Town 2015 Investigating mitochondrial disorders in the South African context: meeting diversity with modern-day science.

Award winners

Welcome by the local organizers

Dear participants:

Welcome to MiPschool, March 2015 in Cape Town, South Africa.

It is my great pleasure to welcome you all to the Mitochondrial Physiology School in Cape Town, South Africa. The school will be held at the University of Cape Town Graduate School of Business, located at the magnificent Cape Town waterfront. All participants will be resident at the venue.

The focus of the school is to combine state-of-the art lectures by international and local experts with hands-on analyses of aspects of mitochondrial function and morphology using different technologies. Several techniques of mitochondrial analyses will be presented to enable participants make informed choices for their own research needs. It is our desire that by the end of the three-day school, participants will have gained a better understanding of the advantages and limitations of the available techniques currently used to study mitochondrial function and the rapid advances that have been made in the field of mitochondrial physiology. Other important objectives of the school are: 1) to provide an opportunity for participants to present their research interests to participants for constructive comments using oral (PowerPoint) or poster formats and 2) to enlarge “mitochondrial networks”. The oral presentations shall last 7 min each (+3 min questions and answers) and formal poster presentations, 3+2 min.

Arrangements have been made for participants to tour interesting places in the Cape Town area including Table Mountain, Robin Island, wine routes and Cape Town Waterfront. The gala dinner, showcasing South Africa’s rich musical and dancing heritage, will crown the MiPschool experience. These events, which are intended to expose participants to the rich, diverse and very fascinating culture of Cape Town and its surrounds; including its peoples, foods, music and dances, are bound to be unforgettable. We warmly invite you to be part of this experience in March 2015.

A one-and-half day pre-MiPschool O2k-Workshop will take place from 23rd to 24th March 2015 at the Research Unit for Exercise Science & Sports Medicine, University of Cape Town, Newlands. A separate registration for this workshop is required.

For further questions, please do not hesitate to contact Deidre Raubenheimer or Edward Ojuka.

Edward Ojuka

Organizer, MiPschool, March 2015

Cape Town, South Africa.

Welcome address by the Chair of the MiPsociety

This MiPschool, March 2015 - the Mitochondrial Physiology School taking place in Cape Town in March 2015 – is the 7th MiPschool organized by the Mitochondrial Physiology Society. Complementary to the International MiPconferences, the first two MiPschools 2007 and 2008 were organised in Schröcken, Austria, the birth place of the MiPsociety. Subsequently, MiPschools were held at Louisiana State University, Baton Rouge, USA (2009); Druskininkai, Lithuania (2010); University of Cambridge, UK (2012); and University of Copenhagen, Denmark (2013).

MiPschools are open to graduate students, postdocs, scientists from academia and biotechnology/pharmaceutical companies, and related entities. The aim is to provide information on current concepts and trends in mitochondrial physiology, ranging from basic to biomedical and clinical perspectives. Despite its strong base in Europe, MiPschools are now spreading to all continents in close cooperation with national and international organizations. To support these aims, I invite you, on behalf of the society, to join us at the MiPschool, March 2015 in Cape Town, South Africa and to become a member of MiPsociety.

Erich Gnaiger

Chair, Mitochondrial Physiology Society
Medical University of Innsbruck
Department of Visceral, Transplant and Thoracic Surgery
D. Swarovski Research Laboratory
A-6020 Innsbruck, Austria


DISCLAIMER: Erich Gnaiger is founder and managing director of OROBOROS INSTRUMENTS – www.oroboros.at

Recommended reading

A hard copy of this monograph on mitochondrial physiology will be included in the MiPschool material. It is available on-line free of charge and provides a background on OXPHOS analysis: From oxygen concentration to oxygen flux •• Membrane potential: electric and chemical forces •• Coupling and efficiency •• Biochemical thresholds •• Respiratory states •• MitoPathways to electron transfer complexes •• Normalization of mitochondrial respiration: coupling control and substrate control.

MITOEAGLE will be presented and discussed at MiPschool Cape Town.

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