Kuznetsov AV

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Name Kuznetsov Andrey,
Institution Cardiac Research Laboratory

Department of Cardiac Surgery

Address ,
City Innsbruck
State/Province
Country Austria
Email
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O2k-Network Lab AT Innsbruck OROBOROS


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Publications

 PublishedReference
Bagur 2016 Biochim Biophys Acta2016Bagur R, Tanguy S, Foriel S, Grichine A, Sanchez C, Pernet-Gallay K, Kaambre T, Kuznetsov AV, Usson Y, Boucher F, Guzun R (2016) The impact of cardiac ischemia/reperfusion on the mitochondria-cytoskeleton interactions. Biochim Biophys Acta 1862:1159-71.
Guzun 2015 Acta Physiol (Oxf)2015Guzun R, Kaambre T, Bagur R, Grichine A, Usson Y, Varikmaa M, Anmann T, Tepp K, Timohhina N, Shevchuk I, Chekulayev V, Boucher F, Dos Santos P, Schlattner U, Wallimann T, Kuznetsov AV, Dzeja P, Aliev M, Saks V (2015) Modular organization of cardiac energy metabolism:energy conversion, transfer and feedback regulation. Acta Physiol (Oxf) 213:84-106.
Kuznetsov 2015 Biochim Biophys Acta2015Kuznetsov AV, Javadov S, Sickinger S, Frotschnig S, Grimm M (2014) H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation. Biochim Biophys Acta 1853:276-84.
Varikmaa 2014 Biochim Biophys Acta2014Varikmaa M, Bagur R, Kaambre T, Grichine A, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Metsis M, Boucher F, Saks V, Kuznetsov AV, Guzun R (2014) Role of mitochondria-cytoskeleton interactions in respiration regulation and mitochondrial organization in striated muscles. Biochim Biophys Acta 1837:232-45.
Wiedemann 2013 Int J Mol Sci2013Wiedemann D, Schachner T, Bonaros N, Dorn M, Andreas M, Kocher A, Kuznetsov AV (2013) Impact of cold ischemia on mitochondrial function in porcine hearts and blood vessels. Int J Mol Sci 14:22042-51.
Hagenbuchner 2013 Oncogene2013Hagenbuchner J, Kuznetsov AV, Obexer P, Ausserlechner MJ (2013) BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene 32:4748-57.
Gonzalez-Granillo 2012 J Mol Cell Cardiol2012Gonzalez-Granillo M, Grichine A, Guzun R, Usson Y, Tepp K, Chekulayev V, Shevchuk I, Karu-Varikmaa M, Kuznetsov AV, Grimm M, Saks V, Kaambre T (2012) Studies of the role of tubulin beta II isotype in regulation of mitochondrial respiration in intracellular energetic units in cardiac cells. J Mol Cell Cardiol 52:437-47.
Kuznetsov 2012 Biochem J2012Kuznetsov AV, Guzun R, Boucher F, Bagur R, Kaambre T, Saks V (2012) Mysterious Ca2+-independent muscular contraction: déjà vu. Biochem J 445:333-6.
Hagenbuchner 2012 J Cell Sci2012Hagenbuchner J, Kuznetsov AV, Hermann M, Hausott B, Obexer P, Ausserlechner MJ (2012) FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3. J Cell Sci 125:1191-1203.
Kuznetsov 2011 Biochim Biophys Acta2011Kuznetsov AV, Margreiter R, Amberger A, Saks V, Grimm M (2011) Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death. Biochim Biophys Acta 1813:1144-52.
Tepp 2011 Biochim Biophys Acta2011Tepp K, Shevchuk I, Chekulayev V, Timohhina N, Kuznetsov AV, Guzun R, Saks V, Kaambre T (2011) High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units. Biochim Biophys Acta 1807: 1549-1561.
Guzun 2011 Biochim Biophys Acta2011Guzun R, Karu-Varikmaa M, Gonzalez-Granillo M, Kuznetsov AV, Michel L, Cottet-Rousselle C, Saaremäe M, Kaambre T, Metsis M, Grimm M, Auffray C, Saks V (2011) Mitochondria–cytoskeleton interaction: Distribution of β-tubulins in cardiomyocytes and HL-1 cells. Biochim Biophys Acta 1807:458-69.
Monge 2009 Can J Physiol Pharmacol 87:318-326.2009Monge C, Beraud N, Tepp K, Pelloux S, Chahboun S, Kaambre T, Kadaja L, Roosimaa M, Piirsoo A, Tourneur Y, Kuznetsov AV, Saks V, Seppet E (2009) Comparative analysis of the bioenergetics of adult cardiomyocytes and nonbeating HL-1 cells: respiratory chain activities, glycolytic enzyme profiles, and metabolic fluxes. Can J Physiol Pharmacol 87:318-26.
Guzun 2009 Biochim Biophys Acta2009Guzun R, Timohhina N, Tepp K, Monge C, Kaambre T, Sikk P, Kuznetsov AV, Pison C, Saks V (2009) Regulation of respiration controlled by mitochondrial creatine kinase in permeabilized cardiac cells in situ. Importance of system level properties. Biochim Biophys Acta 1787:1089-105.
Kuznetsov 2008 Nat Protoc2008Kuznetsov AV, Veksler V, Gellerich FN, Saks V, Margreiter R, Kunz WS (2008) Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat Protoc 3:965-76.
Monge 2008 Mol Cell Biochem2008Monge C, Beraud N, Kuznetsov AV, Rostovtseva T, Sackett D, Schlattner U, Vendelin M, Saks V (2008) Regulation of respiration in brain mitochondria and synaptosomes: restrictions of ADP diffusion in situ, roles of tubulin, and mitochondrial creatine kinase. Mol Cell Biochem 318:147-65.
Schneeberger 2008 Shock2008Schneeberger S, Kuznetsov AV, Seiler R, Renz O, Meusburger H, Mark W, Brandacher G, Margreiter R, Gnaiger E (2008) Mitochondrial ischemia-reperfusion injury of the transplanted rat heart: improved protection by preservation versus cardioplegic solutions. Shock 30:365-71.
Anmann 2005 FEBS J2005Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet EK, Saks VA (2005) Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J 272:3145-61.
Kuznetsov 2004 Am J Physiol Heart Circ Physiol2004Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Mark W, Steurer W, Saks V, Usson Y, Margreiter R, Gnaiger E (2004) Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am J Physiol Heart Circ Physiol 286:H1633–41.
Saks 2003 Biophys J2003Saks V, Kuznetsov A, Andrienko T, Usson Y, Appaix F, Guerrero K, Kaambre T, Sikk P, Lemba M, Vendelin M (2003) Heterogeneity of ADP diffusion and regulation of respiration in cardiac cells. Biophys J 84:3436-56.
Andrienko 2003 J Exp Biol2003Andrienko T, Kuznetsov AV, Kaambre T, Usson Y, Orosco A, Appaix F, Tiivel T, Sikk P, Vendelin M, Margreiter R, Saks VA (2003) Metabolic consequences of functional complexes of mitochondria, myofibrils and sarcoplasmic reticulum in muscle cells. J Exp Biol 206:2059-72.
Appaix 2003 Exp Physiol2003Appaix F, Kuznetsov AV, Usson Y, Kay L, Andrienko T, Olivares J, Kaambre T, Sikk P, Margreiter R, Saks V (2003) Possible role of cytoskeleton in intracellular arrangement and regulation of mitochondria. Exp Physiol 88:175-90.
Kuznetsov 2003 Anal Biochem2003Kuznetsov AV, Kunz WS, Saks V, Usson Y, Mazat J-P, Letellier T, Gellerich FN, Margreiter R (2003) Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers. Anal Biochem 319:296-303.
Wiedemann 2002 Recent Res Devel Anal Biochem2002Wiedemann FR, Winkler K, Kuznetsov AV, Halloul Z, Wallesch C-W, Kunz WS (2002) Recent Res Devel Anal Biochem 2:29-43.
Gnaiger 2002 Biochem Soc Trans2002Gnaiger E, Kuznetsov AV (2002) Mitochondrial respiration at low levels of oxygen and cytochrome c. Biochem Soc Trans 30:242-8.
Kuznetsov 2002 Anal Biochem2002Kuznetsov AV, Strobl D, Ruttmann E, Königsrainer A, Margreiter R, Gnaiger E (2002) Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem 305:186-94.
Stadlmann 2002 Transplantation2002Stadlmann S, Rieger G, Amberger A, Kuznetsov AV, Margreiter R, Gnaiger E (2002) H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation 74:1800-3.
Gnaiger 2000 Life in the Cold2000
O2k-Protocols contents
Gnaiger E, Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Steurer W, Margreiter R (2000) Mitochondria in the cold. In: Life in the Cold (Heldmaier G, Klingenspor M, eds) Springer, Heidelberg, Berlin, New York:431-42.
Kuznetsov 2000 Transplant Proc2000Kuznetsov AV, Brandacher G, Steurer W, Margreiter R, Gnaiger E (2000) Isolated rat heart mitochondria and whole heart as models for mitochondrial cold ischemia-reperfusion injury. Transplant Proc 32:45.
Gnaiger 2000 Transplant Proc2000Gnaiger E, Kuznetsov AV, Königsrainer A, Margreiter R (2000) Autooxidation of glutathione in organ preservation solutions. Transplant Proc 32:14.
Gnaiger 2000 Transpl Int2000Gnaiger E, Kuznetsov AV, Rieger G, Amberger A, Fuchs A, Stadlmann S, Eberl T, Margreiter R (2000) Mitochondrial defects by intracellular calcium overload versus endothelial cold ischemia/reperfusion injury. Transpl Int 13:555-7.
Kunz 1999 J Neurochem1999Kunz WS, Kuznetsov AV, Clark JF, Tracey I, Elger CE (1999) Metabolic consequences of the cytochrome c oxidase deficiency in brain of copper-deficient Movbr mice. J Neurochem 72:1580-5.
Kuznetsov 1999 Transplant Proc1999Kuznetsov AV, Brandacher G, Steurer W, Margreiter R, Gnaiger E (1999) Estimation of mitochondrial damage in heart preservation. Transplant Proc 31:992.
Stadlmann 1999 Transplant Proc1999Stadlmann S, Amberger A, Kuznetsov AV, Rieger G, Hengster P, Margreiter R, Gnaiger E (1999) Does H2O2-mediated oxidative stress reproduce mitochondrial cold preservation/reoxygenation injury in endothelial cells? Transplant Proc 31:993.
Gnaiger 1998 Biochim Biophys Acta1998Gnaiger E, Lassnig B, Kuznetsov AV, Margreiter R (1998) Mitochondrial respiration in the low oxygen environment of the cell: Effect of ADP on oxygen kinetics. Biochim Biophys Acta 1365:249-54.
Saks 1998 Mol Cell Biochem1998Saks VA, Veksler VI, Kuznetsov AV, Kay L, Sikk P, Tiivel T, Tranqui L, Olivares J, Winkler K, Wiedemann F, Kunz WS (1998) Permeabilised cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem 184:81-100.
Gnaiger 1998 J Exp Biol1998Gnaiger E, Lassnig B, Kuznetsov AV, Rieger G, Margreiter R (1998) Mitochondrial oxygen affinity, respiratory flux control, and excess capacity of cytochrome c oxidase. J Exp Biol 201:1129-39.
Kuznetsov 1998 BTK1998Kuznetsov AV, Lassnig B, Margreiter R, Gnaiger E (1998) Diffusion limitation of oxygen versus ADP in permeabilized muscle fibers. In BioThermoKinetics in the Post Genomic Era (Larsson C, Påhlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:273-6.
Lassnig 1998 BTK1998Lassnig B, Kuznetsov AV, Margreiter R, Gnaiger E (1998) Aerobic-anoxic transitions and regulation of mitochondrial oxygen flux. In BioThermoKinetics in the Post Genomic Era (Larsson C, Påhlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:312-6.
Wiedemann 1998 J Neurol Sci1998Wiedemann FR, Winkler K, Kuznetsov AV, Bartels C, Vielhaber S, Feistner H, Kunz WS (1998) Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. J Neurol Sci 156:65-72.
Gnaiger 1998 BTK-HRR1998Gnaiger E, Kuznetsov AV, Lassnig B, Fuchs A, Reck M, Renner K, Stadlmann S, Rieger G, Margreiter R (1998) High-resolution respirometry. Optimum permeabilization of the cell membrane by digitonin. In BioThermoKinetics in the Post Genomic Era (Larsson C, Pahlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:89-95.
Gnaiger 1998 BTK-COX1998Gnaiger E, Kuznetsov AV, Lassnig B, Margreiter R (1998) Functional interpretation of the flux control coefficient and excess capacity of cytochrome c oxidase at intracellular oxygen. In BioThermo-Kinetics in the Post Genomic Era (Larsson C, Påhlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:81-8.
Kunz 1997 Mol Cell Biochem1997Kunz WS, Winkler K, Kuznetsov AV, Lins H, Kirches E, Wallesch CW (1997) Detection of mitochondrial defects by laser fluorimetry. Mol Cell Biochem 174:97-100.
Kuznetsov 1997 Biochim Biophys Acta1997Kuznetsov AV, Winkler K, Kirches E, Lins H, Feistner H, Kunz WS (1997) Application of inhibitor titrations for the detection of oxidative phosphorylation defects in saponin-skinned muscle fibers of patients with mitochondrial diseases. Biochim Biophys Acta 1360:142-50.
Kirches 1996 Saponin1996Kirches E, Winkler K, Kuznetsov AV, Lins H, von Bossanyi P, Dietzmann K, Frank B, Feistner H, Kunz WS (1996) Laserfluoreszenz-Studien der Mitochondrienfunktion in Saponin-permeabilisierten Skelettmuskelfasern von Patienten mit chronisch progressiver externer Ophthalmoplegie. Jahrb Neuromusk Erkrankungen 1996, Arcis Verlag:166-9.
Kuznetsov 1996 Jahrb Neuromusk Erkrankungen1996Kuznetsov AV, Clark JF, Kunz WS (1996) Die Zunahme des Flußkontrollkoeffizienten der Cytochrom-C-Oxidase in Kupfer-defizienten Mobr Mäusen. Jahrb. Neuromusk. Erkrankungen 1996, Arcis Verlag: 170-174.
Kuznetsov 1996 J Biol Chem1996Kuznetsov AV, Clark JF, Winkler K, Kunz WS (1996) Increase of flux control of cytochrome c oxidase in copper-deficient mottled brindled mice. J Biol Chem 271:283-8.
Winkler 1995 Biochim Biophys Acta1995Winkler K, Kuznetsov AV, Lins H, Kirches E, von Bossanyi P, Dietzmann K, Frank B, Feistner H, Kunz WS (1995) Laser-excited fluorescence studies of mitochondrial function in saponin-skinned skeletal muscle fibers of patients with chronic progressive external ophthalmoplegia. Biochim Biophys Acta 1272:181-4.
Kuznetsov 1994 BTK-2751994
BTK1994
Kuznetsov AV, Clark JF, Winkler K, Kunz WS (1994) Change in flux control coefficient of cytochrome c oxidase in copper deficient mottled brindled mice. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:275-77.
Kunz 1994 Anal Biochem1994Kunz WS, Kuznetsov AV, Winkler K, Gellerich FN, Neuhof S, Neumann HW (1994) Measurement of fluorescence changes of NAD(P)H and fluorescent flavoproteins in saponin-skinned fibers. Anal Biochem 216:322-7.
Khuchua 1994 Biochim Biophys Acta1994Khuchua ZA, Kuznetsov AV, Schild L, Neumann HW, Kunz WS (1994) The influence of caffeine and Ca2+ on oxidative phosphorylation in saponin-skinned human skeletal muscle fibers. Biochim Biophys Acta 1188:373-9.
Kunz 1993 FEBS Lett1993Kunz WS, Kuznetsov AV, Gellerich FN (1993) Mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers is stimulated by caffeine. FEBS Lett 323:188-90.
Kunz 1993 Biochim Biophys Acta1993Kunz WS, Kuznetsov AV, Schulze W, Eichhorn K, Schild L, Striggow F, Bohnensack R, Grasshoff H, Neumann HW, Gellerich FN (1993) Functional characterization of mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers. Biochim Biophys Acta 1144:46-53.
Veksler 1987 Biochim Biophys Acta1987Veksler VI, Kuznetsov AV, Sharov VG, Kapelko VI, Saks VA (1987) Mitochondrial respiratory parameters in cardiac tissue: A novel method of assessment by using saponin-skinned fibers. Biochim Biophys Acta 892: 191-196.

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