Hoppel CL

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Evolution-Age-Gender-Lifestyle-Environment  » COST Action CA15203 Mitochondrial fitness mapping

Hoppel CL

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1

Name Hoppel Charles L, Prof., MD

Professor, Pharmacology and Medicine

Chief, Clinical Pharmacology

Director, the Center for Mitochondrial Diseases

Charles Hoppel

Department of Pharmacology

Case Western Reserve University School of Medicine

Address W147 Wood Building, 10900 Euclid Avenue, 44106-4981
City Cleveland
State/Province Ohio (OH)
Country USA
Email charles.hoppel@case.edu
Weblink Department of Pharmacology
O2k-Network Lab US OH Cleveland Hoppel CL



Published Reference
Davuluri 2016 J Physiol 2016 Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol [Epub ahead of print].
Solinas 2014 Mech Ageing Dev 2014 Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4.
Ye 2013 Anal Biochem 2013 Ye F, Hoppel CL (2013) Measuring oxidative phosphorylation in human skin fibroblasts. Anal Biochem 437:52-8.
Rosca 2011 Biochim Biophys Acta 2011 Rosca M, Minkler P, Hoppel CL (2011) Cardiac mitochondria in heart failure: Normal cardiolipin profile and increased threonine phosphorylation of Complex IV. Biochim Biophys Acta 1807:1373-82.
Ye 2011 J Biol Chem 2011 Ye F, Lemieux H, Hoppel CL, Hanson RW, Hakimi P, Croniger CM, Puchowicz M, Anderson VE, Fujioka H, Stavnezer E (2011) Peroxisome proliferator-activated receptor γ (PPARγ) mediates a Ski-induced shift from glycolysis to oxidative energy metabolism. J Biol Chem 286:40013-24.
Lemieux 2010 J Gerontol A Biol Sci Med Sci 2010 Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL (2010) Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J Gerontol A Biol Sci Med Sci 65:1157-64.
Lemieux 2009 JBB 2009 Lemieux H, Hoppel CL (2009) Mitochondria in the human heart. J. Bioenerg. Biomembr. 41:99-106.
Rosca 2008 Cardiovasc Res 2008 Rosca MG, Vazquez EJ, Kerner J, Parland W, Chandler MP, Stanley W, Sabbah HN, Hoppel CL (2008) Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc Res 80:30-39.
Puchowicz 2004 Mitochondrion 2004 Puchowicz MA, Varnes ME, Cohen BH, Friedman NR, Kerr DS, Hoppel CL (2004) Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria-case studies. Mitochondrion 4:377-85.


Published Reference
Hoppel 2016c Abstract MitoFit Science Camp 2016 2016 Mitochondrial respiration in permeabilized skin fibroblasts.
Hoppel 2016a Abstract MitoFit Science Camp 2016 2016 Skeletal muscle mitochondria in diagnostic studies.
Hsiao 2016 Abstract MitoFit Science Camp 2016 2016 Association between mitochondrial bioenergetics and radiation-related fatigue: a possible mechanism and novel target.
Hoppel 2016b Abstract MitoFit Science Camp 2016 2016 Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects.
Lai 2014 Abstract2 MiP2014 2014 Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes.
Lai 2014 Abstract1 MiP2014 2014 Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle.
Hoppel 2012 Abstract Bioblast 2012 Hoppel CL (2012) Mitochondrial functional testing – muscle biopsy, isolated mitochondria and others. Mitochondr Physiol Network 17.12.
Rosca MiP2010 2010 Rosca MG, Hoppel CL (2010) Activation of distinct mitochondrial cAMP-PKA compartments induces different effects on mitochondrial function.


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