Doerrier Velasco CA

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Doerrier Velasco CA


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1 COST WG2: WG2 COST WG3: WG3 COST WG4: WG4


Name Doerrier Velasco Carolina A, PhD, Chief Scientific Officer, Mitochondrial Application Specialist
Institution
Carolina Doerrier

OROBOROS INSTRUMENTS

O2k high-resolution respirometry

Address Schoepfstr. 18, 6020
City Innsbruck
State/Province
Country Austria
Email carolina.doerrier@oroboros.at
Weblink www.oroboros.at, www.bioblast.at, www.mitophysiology.org
O2k-Network Lab AT Innsbruck OROBOROS, ES Granada Acuna-Castroviejo D


Labels: Field of research: Basic  Topics: High-resolution respirometry, Mitochondria, Melatonin, Reactive oxygen species, Reactive nitrogen species, Sepsis 


Publications

Published Reference
Doerrier 2016 Mitochondrion 2016 Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Volt 2016 J Pineal Res 2016 Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Melatonin 2015 Doerrier C (2015) Melatonin and attenuation of mitochondrial oxidative damage. Mitochondr Physiol Network 2015-03-03.
Doerrier 2015 Thesis 2015 Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.
Garcia 2015 FASEB J 2015 García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
Ortiz 2015 J Pineal Res 2015 Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
García-Corzo 2015 Biochim Biophys Acta 2015 García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Ortiz 2014 J Pineal Res 2014 Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Doerrier 2014 Life Sci 2014 Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Concepcion-Huertas 2013 J Sports Sci 2013 Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Garcia-Corzo 2013 Hum Mol Genet 2013 García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Escames 2013 Horm Mol Biol Clin Investig 2013 Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Acuña-Castroviejo 2012 Age (Dordr) 2012 Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.


Abstracts

Published Reference
Volani 2016 Abstract MitoFit Science Camp 2016 2016 Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.
Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck 2016 Searching specific targets of ischemic damage of cardiac mitochondria using O2k-fluorometry.
Sumbalova 2016a Abstract MitoFit Science Camp 2016 2016 Optimizing strategies on the malate concentration in SUIT protocols.
Bezuidenhout 2016a Abstract MitoFit Science Camp 2016 2016 Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Doerrier 2016c Abstract Mito Xmas Meeting Innsbruck 2016 MitoFit and MITOEAGLE – towards a global data bank on mitochondrial physiology.
Gnaiger 2016 Abstract SFRR Australasia 2016 2016 Facts and artefacts in measurements of H2O2 production under hypoxia.
Bezuidenhout 2016b Abstract MitoFit Science Camp 2016 2016 Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.
Krumschnabel 2016a Abstract MitoFit Science Camp 2016 2016 O2k-Protocols: Mitochondrial preparations for HRR.
Doerrier 2016a Abstract Mito Xmas Meeting Innsbruck 2016
MitoFit
MitoFit and MITOEAGLE – towards a global data bank on mitochondrial physiology.
Doerrier 2016 Abstract MitoFit Science Camp 2016 2016 Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Gnaiger 2016 Abstract EBEC Riva del Garda 2016 2016 MitoFit and MITOEAGLE – towards a global data bank on mitochondrial physiology.
Volani 2016 Abstract Mito Xmas Meeting Innsbruck 2016 Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.
Volani 2015 Abstract IOC106 2015 Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.
Doerrier 2015 Abstract MiPschool Greenville 2015 2015 "Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Gnaiger 2015 Abstract MiP2015 2015 Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.
Doerrier 2015 Abstract MiP2015 2015 Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Doerrier 2014 Abstract SECF 2014 Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Luna-Sánchez 2014 Abstract SECF 2014 Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF 2014 Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF 2014 Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF 2014 Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit 2014 Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Ortiz 2013 Abstract SEOR 2013 Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Doerrier 2012 Abstract Bioblast 2012 Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Escames 2012 Abstract ESTRO 2012 Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge 2012 CoQ deficiency: molecular and phathophysiological consequences.
Luna-Sánchez 2012 Abstract FEPS&SECF 2012 CoQ deficiency: Molecular and pathophysiological consequences.
Garcia-Corzo 2011 Abstract Euromit 8 2011 Generation of a mouse model of Coenzyme Q deficiency.
Escames 2011 Abstract FASEB Summer Research Conference 2011 Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.

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