Doerrier Velasco CA

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Doerrier Velasco CA


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1 COST WG2: WG2 COST WG3: WG3 COST WG4: WG4


Name Doerrier Velasco Carolina A, PhD, Chief Scientific Officer, Mitochondrial Application Specialist
Institution
Carolina Doerrier

OROBOROS INSTRUMENTS

O2k high-resolution respirometry

Address Schoepfstr. 18, 6020
City Innsbruck
State/Province
Country Austria
Email carolina.doerrier@oroboros.at
Weblink www.oroboros.at, www.bioblast.at, www.mitophysiology.org
O2k-Network Lab AT Innsbruck OROBOROS, ES Granada Acuna-Castroviejo D


Labels: Field of research: Basic  Topics: High-resolution respirometry, Mitochondria, Melatonin, Reactive oxygen species, Reactive nitrogen species, Sepsis 


Publications

 PublishedReference
Volt 2016 J Pineal Res2016Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Doerrier 2016 Mitochondrion2016Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
García-Corzo 2015 Biochim Biophys Acta2015García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Melatonin2015Doerrier C (2015) Melatonin and attenuation of mitochondrial oxidative damage. Mitochondr Physiol Network 2015-03-03.
Garcia 2015 FASEB J2015García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
Ortiz 2014 J Pineal Res2014Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Escames 2013 Horm Mol Biol Clin Investig2013Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Garcia-Corzo 2013 Hum Mol Genet2013García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Concepcion-Huertas 2013 J Sports Sci2013Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Acuña-Castroviejo 2012 Age (Dordr)2012Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.

Abstracts

 PublishedReference
Bezuidenhout 2016b Abstract MitoFit Science Camp 20162016Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.
Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck2016Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.
Krumschnabel 2016a Abstract MitoFit Science Camp 20162016O2k-Protocols: Mitochondrial preparations for HRR.
Volani 2016 Abstract Mito Xmas Meeting Innsbruck2016Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.
Doerrier 2016 Abstract MitoFit Science Camp 20162016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Volani 2016 Abstract MitoFit Science Camp 20162016Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.
Sumbalova 2016a Abstract MitoFit Science Camp 20162016Optimizing strategies on the malate concentration in SUIT protocols.
Gnaiger 2016 Abstract EBEC Riva del Garda 20162016MitoFit and MITOEAGLE – towards a global data bank on mitochondrial physiology.
Gnaiger 2016 Abstract SFRR Australasia 20162016Facts and artefacts in measurements of H2O2 production under hypoxia.
Bezuidenhout 2016a Abstract MitoFit Science Camp 20162016Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Doerrier 2016a Abstract Mito Xmas Meeting Innsbruck2016
MitoFit
MitoFit and MITOEAGLE – towards a global data bank on mitochondrial physiology.
Volani 2015 Abstract IOC1062015Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.
Doerrier 2015 Abstract MiPschool Greenville 20152015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Gnaiger 2015 Abstract MiP20152015Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.
Doerrier 2015 Abstract MiP20152015Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Volt 2014 Abstract The 2014 Ageing Summit2014Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Doerrier 2014 Abstract SECF2014Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Luna-Sánchez 2014 Abstract SECF2014Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF2014Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF2014Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF2014Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Ortiz 2013 Abstract SEOR2013Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Doerrier 2012 Abstract Bioblast2012Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge2012CoQ deficiency: molecular and phathophysiological consequences.
Luna-Sánchez 2012 Abstract FEPS&SECF2012CoQ deficiency: Molecular and pathophysiological consequences.
Escames 2012 Abstract ESTRO2012Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Garcia-Corzo 2011 Abstract Euromit 82011Generation of a mouse model of Coenzyme Q deficiency.
Escames 2011 Abstract FASEB Summer Research Conference2011Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.

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